公开(公告)号：US07029854B2

公开(公告)日：2006-04-18

申请号：US10303151

申请日：2002-11-22

申请人： Patrick J. Collins ,  Keith C. Butler ,  Peter G. Webb ,  Karen W. Shannon ,  Sandra L. Tang

发明人： Patrick J. Collins ,  Keith C. Butler ,  Peter G. Webb ,  Karen W. Shannon ,  Sandra L. Tang

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6876 ,  G06F19/22

摘要： Methods of identifying a sequence of a nucleic acid that is suitable for use as a surface immobilized probe for two or more mRNA transcripts encoded by the same gene are provided. In practicing the subject methods, a consensus region for the two or more transcripts is first identified, and this identified consensus region is then employed to identify the suitable nucleic acid sequence, e.g., by using a probe design protocol. The subject invention also includes algorithms for performing the subject methods recorded on a computer readable medium, as well as computational analysis systems that include the same. Also provided are nucleic acid arrays produced with probes having sequences identified by the subject methods, as well as methods for using the same.

摘要翻译： 提供了鉴定适合用作由相同基因编码的两个或更多个mRNA转录物的表面固定化探针的核酸序列的方法。 在实施本发明方法时，首先鉴定两个或多个转录物的共有区域，然后使用该鉴定的共有区域来鉴定合适的核酸序列，例如通过使用探针设计方案。 本发明还包括用于执行记录在计算机可读介质上的主题方法的算法，以及包括其的计算分析系统。 还提供了由具有由本发明方法鉴定的序列的探针产生的核酸阵列，以及使用该序列的方法。

公开(公告)号：US4381512A

公开(公告)日：1983-04-26

申请号：US11738

申请日：1979-02-13

申请人： Keith C. Butler

发明人： Keith C. Butler

IPC分类号： G01D15/24 ,  G01D9/00 ,  G01D9/14 ,  G01D15/00 ,  G01D9/10

CPC分类号： G01D15/005 ,  G01D9/14

摘要： Apparatus for controlling the stepping of a pen and chart of a recorder is described in which the data is buffered so as to free up the processor. The pen steps as fast as it can and no new data points are read until the pen-stepping data is used up. The chart stepping is keyed to the reading of data points so that while the pen is moving to a desired position, the chart stands still.

摘要翻译： 描述了用于控制记录器的笔和图表的步进的装置，其中数据被缓冲以释放处理器。 钢笔的步伐尽可能快，直到笔式数据用完，才能读取新的数据点。 图表步进是数据点读取的关键，所以当笔移动到所需的位置时，图表静止不动。