公开(公告)号：US20110111012A1

公开(公告)日：2011-05-12

申请号：US12590712

申请日：2009-11-12

Applicant: Clinton B. Pepper ,  Simon McCarthy ,  Keith Real ,  Jess Kimball ,  Jana Ruzickova ,  Jana Svobodova ,  Lucia Silovska ,  Jitka Vankova ,  Jiri Machat ,  Radim Dvorak

Inventor： Clinton B. Pepper ,  Simon McCarthy ,  Keith Real ,  Jess Kimball ,  Jana Ruzickova ,  Jana Svobodova ,  Lucia Silovska ,  Jitka Vankova ,  Jiri Machat ,  Radim Dvorak

IPC: A61K9/70 ,  A61K33/38 ,  A61K38/16 ,  A61K31/715 ,  A61K31/722 ,  A61K31/717 ,  A61P19/02 ,  B32B37/02 ,  B29C47/00

CPC classification number: B32B38/0004 ,  A61F13/00995 ,  A61F2013/00463 ,  A61F2013/00931 ,  A61F2013/00936 ,  B32B37/00 ,  B32B2535/00 ,  Y10T156/10

Abstract: Wound dressing assemblies and methods of producing the wound dressing assemblies. The wound dressing assemblies various comprise individual layers of nanomaterials that have been formed according to an electrospinning process.Each of the layers can have different characteristics and qualities. The invention also provides guidance in selecting materials to form a wound dressing assembly, as well as possible adaptations to the electrospinning process to provide different characteristics for particular materials.

Abstract translation: 伤口敷料组件及其制造方法。 伤口敷料组件各种包括根据静电纺丝工艺形成的纳米材料的单独层。 每个层可以具有不同的特征和质量。 本发明还提供了选择材料以形成伤口敷料组件的指导，以及可能适应于静电纺丝过程以为特定材料提供不同特性。

公开(公告)号：US20130110025A1

公开(公告)日：2013-05-02

申请号：US13808183

申请日：2011-07-04

Applicant: Peter Donnellan ,  Marie Ni Beiliu ,  Keith Real

Inventor： Peter Donnellan ,  Marie Ni Beiliu ,  Keith Real

IPC: A61F13/00

CPC classification number: A61F13/00063 ,  A61L15/26 ,  A61L15/46 ,  A61L2300/206 ,  A61L2300/232 ,  A61L2300/404 ,  A61L2300/418 ,  A61L2300/45 ,  A61L2400/04 ,  C08L75/04

Abstract: A wound dressing device for use with a transcutaneous medical device such as a cannula or a catheter comprises a polyurethane matrix which may be covered with a film backing. Chlorhexidine di- gluconate and a polyanhydroglucuronic salt are contained in the polymer matrix. The wound dressing device prevents microbial colonization of the dressing and stops bleeding from the insertion site. The device provides combined haemostatic and antimicrobial effects at the insertion site but without adversely affecting wound healing.

Abstract translation: 用于与经皮医疗装置如套管或导管一起使用的伤口敷料装置包括可覆盖有膜背衬的聚氨酯基质。 聚合物基质中含有氯己定二葡萄糖酸盐和聚缩水甘油醛酸盐。 伤口敷料装置防止敷料的微生物定居，并阻止插入部位渗出。 该装置在插入部位提供组合的止血和抗微生物作用，但不会不利地影响伤口愈合。

公开(公告)号：US20100266646A1

公开(公告)日：2010-10-21

申请号：US12657922

申请日：2010-01-29

Applicant: Radim Dvorak ,  Julieann Doyle ,  Keith Real

Inventor： Radim Dvorak ,  Julieann Doyle ,  Keith Real

IPC: A61K8/73 ,  A61K8/02 ,  A61Q19/08 ,  C08B1/00

CPC classification number: A61K8/731 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/522 ,  A61Q19/007 ,  A61Q19/08 ,  B82Y5/00 ,  Y10T428/29

Abstract: A refined oxidised cellulose (OC) material in various salt states having therapeutic treatments for skin. The micronized OC has a uniform particle size of the order of microns (0.001 to 0.050 mm). The OC is treated by further steps of oxidation, hydrolysis and refinement. The final product is chemically known as polyanhydroglucuronic acid, (PAGA). The salt versions of the OC are generally metal salts, such as sodium, calcium, zinc, copper, and silver.

Abstract translation: 具有治疗皮肤治疗的各种盐状态的精制氧化纤维素（OC）材料。 微粉化的OC具有微米级（0.001至0.050mm）的均匀粒度。 通过进一步的氧化，水解和精制步骤处理OC。 最后的产物是化学上称为聚酐的缩水甘油酸（PAGA）。 OC的盐型通常是金属盐，例如钠，钙，锌，铜和银。