公开(公告)号：US5763598A

公开(公告)日：1998-06-09

申请号：US876979

申请日：1997-06-16

申请人： Kenichi Hamayasu ,  Tetsuya Ito ,  Koki Fujita ,  Kozo Hara ,  Kyoko Koizumi ,  Toshiko Tanimoto ,  Hirofumi Nakano ,  Sumio Kitahata

发明人： Kenichi Hamayasu ,  Tetsuya Ito ,  Koki Fujita ,  Kozo Hara ,  Kyoko Koizumi ,  Toshiko Tanimoto ,  Hirofumi Nakano ,  Sumio Kitahata

IPC分类号： C12P19/26 ,  A61K47/48 ,  C08B37/16 ,  A01N43/04 ,  A61K31/715

CPC分类号： B82Y5/00 ,  A61K47/48969 ,  C08B37/0012

摘要： Disclosed are novel branched cyclodextrins having any of an N-acetylglucosamine group, a glucosaminyl group, an N-acetylgalactosaminyl group and a galactosaminyl group as bonded to the hydroxyl group of the cyclodextrin ring by .beta.-bonding therebetween, and their salts. The novel branched cyclodextrins are produced by reacting a solution containing a cyclodextrin and an N-acetylglucosamine or N-acetylgalactosamine with an N-acetylhexosaminidase, and optionally deacetylating the resulting product.

摘要翻译： 公开了通过β键连接在环糊精环的羟基上的N-乙酰葡糖胺基，葡糖胺基，N-乙酰半乳糖胺基和半乳糖胺基中的任一种的新型支链环糊精及其盐。 新型支链环糊精是通过使含有环糊精和N-乙酰葡糖胺或N-乙酰半乳糖胺的溶液与N-乙酰基己糖胺酶反应，并任选地将所得产物脱乙酰化来制备的。

公开(公告)号：US20090030194A1

公开(公告)日：2009-01-29

申请号：US11913999

申请日：2006-03-30

申请人： Kenichi Hamayasu ,  Hiroki Tadokoro ,  Eriko Kishino ,  Tetsuya Ito ,  Koki Fujita ,  Kozo Hara

发明人： Kenichi Hamayasu ,  Hiroki Tadokoro ,  Eriko Kishino ,  Tetsuya Ito ,  Koki Fujita ,  Kozo Hara

IPC分类号： C07H1/06

CPC分类号： C12P19/02 ,  C12P7/62 ,  C12P17/04

摘要： Provided is a process, by which glucuronic acid and/or glucuronolactone can be produced in high yield, at low cost, in an easy manner and in safe. Also provided is a process for production of glucuronic acid and/or glucuronolactone which is characterized in that sucrose is oxidized to give sucrose carboxylic acid (and a salt thereof) (glucuronyl-fructoside, β-D-fructosyl-(2→1)-α-D-glucuronic acid and a salt thereof), yeast is added so as to hydrolyze fructose residue of the sucrose carboxylic acid and to assimilate the resulting product, and thus produced glucuronic acid and/or glucuronolactone are/is collected.

摘要翻译： 提供了一种以低成本，易于且安全地以高产率生产葡糖醛酸和/或葡糖醛酸内酯的方法。 还提供了用于生产葡糖醛酸和/或葡糖醛酸内酯的方法，其特征在于将蔗糖氧化得到蔗糖羧酸（及其盐）（葡糖醛酸 - 果糖苷，β-D-果糖基 - （2-> 1） -α-D-葡糖醛酸及其盐），加入酵母以水解蔗糖羧酸的果糖残基并使所得产物同化，从而收集葡萄糖醛酸和/或葡糖醛酸内酯。