公开(公告)号：US09086356B2

公开(公告)日：2015-07-21

申请号：US13045966

申请日：2011-03-11

申请人： Thomas L. Kelly ,  Kevin E. Wilson

发明人： Thomas L. Kelly ,  Kevin E. Wilson

IPC分类号： G06K9/00 ,  G01N23/04 ,  A61B6/00 ,  G06T7/00 ,  A61B5/00 ,  A61B6/03

CPC分类号： A61B5/4872 ,  A61B6/032 ,  A61B6/461 ,  A61B6/482 ,  A61B6/50 ,  A61B6/5217 ,  A61B6/5294 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612 ,  G06K9/46 ,  G06K2009/4666 ,  G06T7/0012 ,  G06T7/11 ,  G06T2207/10116

摘要： Dual-energy absorptiometry is used to estimate visceral fat metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing visceral fat as well as subcutaneous fat, at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the visceral fat in the slice, and using the resulting estimates. Processing the measurements includes an algorithm which places boundaries of regions, e.g., a large “abdominal” region and a smaller “abdominal cavity” region. Two boundaries of the “abdominal cavity” region are placed at positions associated with the left and right innermost extent of the abdominal muscle wall by identifying inflection of % Fat values. The regions are combined in an equation that is highly correlated with VAT measured by quantitative computed tomography in order to estimate VAT.

摘要翻译： 双能量吸收测定法用于估计内脏脂肪指标并显示结果，优选与规范数据相关。 该过程包括得出与包含内脏脂肪以及皮下脂肪的身体切片的二维投影图像有关的各个像素位置的x射线测量，至少一些测量是双能X射线测量，处理 测量以得出与切片中的内脏脂肪相关的度量的估计，并使用所得的估计。 处理测量包括放置区域边界的算法，例如大的“腹部”区域和较小的“腹腔”区域。 通过识别％Fat值的变化，将“腹腔”区域的两个边界放置在与腹壁肌肉壁的左内侧和右侧最内侧相关联的位置处。 通过定量计算机断层扫描测量的VAT与高度相关的方程组合，以估算增值税。

公开(公告)号：US08792689B2

公开(公告)日：2014-07-29

申请号：US13217688

申请日：2011-08-25

申请人： Thomas L. Kelly ,  Kevin E. Wilson

发明人： Thomas L. Kelly ,  Kevin E. Wilson

IPC分类号： G06K9/00

CPC分类号： G06T7/0012 ,  G06K9/00 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/10116 ,  G06T2207/20021 ,  G06T2207/30004 ,  G06T2211/408

摘要： Dual-energy absorptiometry is used to estimate intramuscular adipose tissue metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing intramuscular adipose tissue as well as subcutaneous adipose tissue, at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the intramuscular adipose tissue in the slice, and using the resulting estimates. Processing the measurements includes an algorithm which places boundaries of regions, e.g., a large region and a smaller region. The regions are combined in an equation that is highly correlated with intramuscular adipose tissue measured by quantitative computed tomography in order to estimate intramuscular adipose tissue.

摘要翻译： 双能量吸收测定用于估计肌内脂肪组织指标并显示结果，优选与规范数据相关。 该过程涉及对与包含肌内脂肪组织以及皮下脂肪组织的身体切片的二维投影图像相关的各个像素位置获得x射线测量，至少一些测量是双能x射线测量， 处理测量以得出与切片中的肌内脂肪组织相关的度量的估计，并且使用所得到的估计。 处理测量包括放置区域的边界的算法，例如大区域和较小区域。 该区域与通过定量计算机断层扫描测量的肌内脂肪组织高度相关的方程组合，以估计肌内脂肪组织。

公开(公告)号：US07725153B2

公开(公告)日：2010-05-25

申请号：US10958107

申请日：2004-10-04

申请人： Thomas Kelly ,  Kevin E. Wilson ,  Christopher Ruth

发明人： Thomas Kelly ,  Kevin E. Wilson ,  Christopher Ruth

IPC分类号： A61B5/05

CPC分类号： A61B5/4872 ,  A61B6/4035 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/50 ,  A61B6/505

摘要： A system and a method of using dual-energy absoptiometry to estimate visceral fat metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing visceral fat as well as subcutaneous fat; at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the visceral fat in the slice; and using the resulting estimates.

摘要翻译： 优选与规范性数据相关的系统和使用双能量腹膜测量术来估计内脏脂肪量度并显示结果的方法。 该过程包括对与含有内脏脂肪以及皮下脂肪的身体切片的二维投影图像相关的各个像素位置得出x射线测量值; 至少一些测量是双能X射线测量，处理测量以导出与切片中的内脏脂肪相关的度量的估计; 并使用所得的估计。

公开(公告)号：US06496557B2

公开(公告)日：2002-12-17

申请号：US09767286

申请日：2001-01-22

申请人： Kevin E. Wilson ,  Jay A. Stein ,  Richard Cabral ,  Andrew P. Smith ,  Vinnie Quinn

发明人： Kevin E. Wilson ,  Jay A. Stein ,  Richard Cabral ,  Andrew P. Smith ,  Vinnie Quinn

IPC分类号： A61B600

CPC分类号： A61B6/505 ,  A61B6/0457 ,  A61B6/06 ,  A61B6/4233 ,  A61B6/4266 ,  A61B6/4291 ,  A61B6/4441 ,  A61B6/4476 ,  A61B6/482 ,  A61B6/5241 ,  A61B6/544 ,  G01N23/046 ,  G01N2223/419 ,  G01N2223/612

摘要： An x-ray system using a slot-shaped detector having n rows and m columns of pixels, where n

摘要翻译： 一种使用具有n行和m列像素的槽形检测器的x射线系统，其中n << m，并且在患者台和源检测器单元之间提供各种相对运动，包括沿着 桌子上的平移，以及关于焦斑的旋转，以及以各种方式处理像素值以产生诸如阴影图形X射线图像，不需要平面的表面的合成图像以及骨密度的信息 估计。 在另一个实施例中，可以使用将几乎所有主要束传递到成像器同时消除几乎所有散射的患者后准直器来直接获得断层图像。 反馈回路可以基本上实时地对图像的所选部分的曝光进行均衡。

公开(公告)号：US06352512B1

公开(公告)日：2002-03-05

申请号：US09277838

申请日：1999-03-26

申请人： Kevin E. Wilson ,  Donald Barry ,  Dennis G. Lamser ,  John P. O'Brien ,  Jay A. Stein

发明人： Kevin E. Wilson ,  Donald Barry ,  Dennis G. Lamser ,  John P. O'Brien ,  Jay A. Stein

IPC分类号： A61B800

CPC分类号： A61B5/1074 ,  A61B8/0875 ,  A61B8/4209 ,  A61B8/587

摘要： A method of calibrating an ultrasound bone analysis apparatus having a pair of transducer assemblies. Each transducer assembly has a transducer and a coupling pad, and is movable relative to the other so that a face of each pad can be moved to a position in which they mutually contact at a first compression and to a position where the faces contact body parts at a second compression different than the first compression. The method according to the present application includes transmitting an ultrasound signal from one transducer and receiving a signal corresponding to the transmitted ultrasound signal through the other transducer when the transducer assemblies are in the first position and the second position. A time for the ultrasound signal to pass through the body part is determined, and a width of the body part based on positions of the transducers is determined. Then, using the time and width values a speed of sound of the ultrasound signal passing through the body part with squish compensation is calculated.

摘要翻译： 一种校准具有一对换能器组件的超声骨分析装置的方法。 每个换能器组件具有换能器和耦合垫，并且可相对于另一个移动，使得每个垫的表面可以移动到它们在第一压缩下相互接触的位置，并且其中所述面接触体部分 在不同于第一压缩的第二压缩下。 根据本申请的方法包括当换能器组件处于第一位置和第二位置时，从一个换能器发送超声信号并且通过另一个换能器接收与所发射的超声信号相对应的信号。 确定超声信号通过身体部位的时间，并且确定基于换能器的位置的身体部位的宽度。 然后，使用时间和宽度值计算通过身体部位的超声信号的声音的压缩补偿。

公开(公告)号：US6135964A

公开(公告)日：2000-10-24

申请号：US374138

申请日：1999-08-10

申请人： Donald Barry ,  Richard E. Cabral ,  Daniel W. Hawkins ,  Dennis G. Lamser ,  John P. O'Brien ,  Jay A. Stein ,  Kevin E. Wilson

发明人： Donald Barry ,  Richard E. Cabral ,  Daniel W. Hawkins ,  Dennis G. Lamser ,  John P. O'Brien ,  Jay A. Stein ,  Kevin E. Wilson

IPC分类号： A61B8/00 ,  A61B5/107 ,  A61B8/08

CPC分类号： A61B5/1074 ,  A61B8/0875

摘要： An ultrasonic bone testing apparatus has a foot well assembly and a shin guide assembly which are mechanically coupled to secure a foot and lower leg of patient during the measurement process. The shin guide assembly includes a molded form which has a shin restraint section, an instep guide section and a foot restraint section. An instep support guide having sliding blocks is mounted on the molded form. The sliding blocks are inserted into respective channels of respective bridge brackets of the foot well assembly to attach the shin guide assembly to the foot well assembly. The apparatus further includes a transducer drive mechanism for positioning a pair of transducer assemblies. A controller automatically modifies the positioning of the transducer assemblies until ultrasonic coupling is achieved and a receiving transducer receives a signal of a predetermined quality. A coupling pad and acoustical delay line of the transducer assembly provide a waveguide function to collimate an acoustical beam a sufficient distance along a propagation axis to allow wavefronts to evolve onto a more uniform intensity pattern. The elastomer coupling pad has an angled surface which expels air bubbles from a contact area when pressure is applied to the pad.

摘要翻译： 超声骨测试装置具有脚部组件和引导组件，其在测量过程中机械联接以固定患者的脚和小腿。 引导组件包括具有胫部约束部分，脚背引导部分和脚部约束部分的模制形式。 具有滑块的脚背支撑引导件安装在模制形式上。 将滑动块插入到足部井组件的相应桥架支架的相应通道中，以将胫骨引导组件附接到脚部组件。 该装置还包括用于定位一对换能器组件的换能器驱动机构。 控制器自动修改换能器组件的定位，直到实现超声波耦合并且接收换能器接收到预定质量的信号。 换能器组件的耦合垫和声学延迟线提供了波导功能，以沿着传播轴线对声束进行校准足够的距离，以允许波前演化成更均匀的强度图案。 弹性体联接垫具有成角度的表面，当压力施加到垫时，其从接触区域排出气泡。

公开(公告)号：US5949846A

公开(公告)日：1999-09-07

申请号：US794615

申请日：1997-02-03

申请人： Jay A. Stein ,  Howard P. Weiss ,  Vincent E. Quinn ,  Richard E. Cabral ,  John A. Shepherd ,  Kevin E. Wilson

发明人： Jay A. Stein ,  Howard P. Weiss ,  Vincent E. Quinn ,  Richard E. Cabral ,  John A. Shepherd ,  Kevin E. Wilson

IPC分类号： A61B6/00 ,  G01N23/00

CPC分类号： A61B6/505

摘要： A method of measuring bone mineral density (BMD) of a selected region of bone in a small body portion (such as a limb or extremity), using a mini C-arm x-ray fluoroscopic imaging system to acquire the data from which the BMD is calculated. Apparatus for performing the method includes a tray for positioning the small body portion in the x-ray beam path of the imaging system and a sample of bone of predetermined density supported by the tray in side-by-side relation to the selected region of bone.

摘要翻译： 使用小型C型臂X射线透视成像系统来测量小体部（例如肢体或肢体）中骨骼的选定区域的骨矿物质密度（BMD）的方法，以获取BMD 被计算。 用于执行该方法的装置包括用于将小体部分定位在成像系统的x射线束路径中的托盘和由托盘支撑的预定密度的骨样品与所选择的骨区域并排关系 。

公开(公告)号：US09179873B2

公开(公告)日：2015-11-10

申请号：US12730051

申请日：2010-03-23

申请人： Thomas Kelly ,  Kevin E. Wilson ,  Christopher Ruth

发明人： Thomas Kelly ,  Kevin E. Wilson ,  Christopher Ruth

IPC分类号： A61B5/05 ,  A61B5/00 ,  A61B6/00

CPC分类号： A61B5/4872 ,  A61B6/4035 ,  A61B6/4241 ,  A61B6/482 ,  A61B6/50 ,  A61B6/505

摘要： A system and a method of using dual-energy absoptiometry to estimate visceral fat metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing visceral fat as well as subcutaneous fat; at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the visceral fat in the slice; and using the resulting estimates.

摘要翻译： 优选与规范性数据相关的系统和使用双能量腹膜测量术来估计内脏脂肪量度并显示结果的方法。 该过程包括对与含有内脏脂肪以及皮下脂肪的身体切片的二维投影图像相关的各个像素位置得出x射线测量值; 至少一些测量是双能X射线测量，处理测量以导出与切片中的内脏脂肪相关的度量的估计; 并使用所得的估计。

公开(公告)号：US20150036910A1

公开(公告)日：2015-02-05

申请号：US14444547

申请日：2014-07-28

申请人： Thomas L. Kelly ,  Kevin E. Wilson

发明人： Thomas L. Kelly ,  Kevin E. Wilson

IPC分类号： G06T7/00 ,  G06T11/00

CPC分类号： G06T7/0012 ,  G06K9/00 ,  G06T11/008 ,  G06T2207/10081 ,  G06T2207/10116 ,  G06T2207/20021 ,  G06T2207/30004 ,  G06T2211/408

摘要： Dual-energy absorptiometry is used to estimate intramuscular adipose tissue metrics and display results, preferably as related to normative data. The process involves deriving x-ray measurements for respective pixel positions related to a two-dimensional projection image of a body slice containing intramuscular adipose tissue as well as subcutaneous adipose tissue, at least some of the measurements being dual-energy x-ray measurements, processing the measurements to derive estimates of metrics related to the intramuscular adipose tissue in the slice, and using the resulting estimates. Processing the measurements includes an algorithm which places boundaries of regions, e.g., a large region and a smaller region. The regions are combined in an equation that is highly correlated with intramuscular adipose tissue measured by quantitative computed tomography in order to estimate intramuscular adipose tissue.

摘要翻译： 双能量吸收测定用于估计肌内脂肪组织指标并显示结果，优选与规范数据相关。 该过程涉及对与包含肌内脂肪组织以及皮下脂肪组织的身体切片的二维投影图像相关的各个像素位置获得x射线测量，至少一些测量是双能x射线测量， 处理测量以得出与切片中的肌内脂肪组织相关的度量的估计，并且使用所得到的估计。 处理测量包括放置区域的边界的算法，例如大区域和较小区域。 该区域与通过定量计算机断层扫描测量的肌内脂肪组织高度相关的方程组合，以估计肌内脂肪组织。

公开(公告)号：US20100310141A1

公开(公告)日：2010-12-09

申请号：US12452310

申请日：2006-11-10

申请人： Kevin E. Wilson

发明人： Kevin E. Wilson

IPC分类号： G06K9/00 ,  A61B5/00

CPC分类号： G06T7/0012 ,  A61B6/466 ,  A61B6/482 ,  A61B6/505 ,  G06T2200/04 ,  G06T2207/10116 ,  G06T2207/30008

摘要： A novel approach for analyzing a patient's body part of interest to assess bone strength and/or risk of future fracture includes obtaining a priori information regarding the body part of interest, performing X-ray absorptiometric scans of the patient's body part of interest and collecting X-ray absorptiometry data from the scans, constructing a three-dimensional model of the patient's body part of interest, by utilizing the a priori information along with the X-ray absorptiometric data, and performing measurements of various geometric parameters on the three-dimensional model for determining geometric and structural properties.

摘要翻译： 用于分析患者身体部分以评估骨骼强度和/或未来骨折风险的新颖方法包括获得关于感兴趣的身体部位的先验信息，对感兴趣的患者身体部分进行X射线吸收测量扫描并收集X 来自扫描的射线吸收测量数据，通过利用先验信息与X射线吸收测量数据一起构建患者身体部分的三维模型，并对三维模型进行各种几何参数的测量 用于确定几何和结构性质。