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1.发明授权公开(公告)号：US07084122B2
公开(公告)日：2006-08-01
申请号：US10300831
申请日：2002-11-21
申请人： Erik Larsen , Arsalan Kharazmi , Søren Brøgger Christensen , Lars Porskjær Christensen , Kirsten Brandt
发明人： Erik Larsen , Arsalan Kharazmi , Søren Brøgger Christensen , Lars Porskjær Christensen , Kirsten Brandt
IPC分类号： A61K31/70
CPC分类号： A61K31/366 , A61K9/48
摘要： Glycosides of diacylglycerol, e.g. 3-β-D-galactopyranosyloxy-2-(octadeca-9Z,12Z,15Z-trienoyloxy)propanyl octadeca-9Z,12Z,15Z-trienoate (GOPO), which was isolated from extracts of rose-hips by activity guided fractionation, can be used as an oral anti-inflammatory agent for the treatment of inflammatory diseases such as arthritis and osteoarthrosis.
摘要翻译： 二酰基甘油的糖苷，例如 可以通过活性引导分馏从玫瑰果提取物中分离出3-β-D-吡喃半乳糖氧基-2-（十八烷-9Z，12Z，15Z-三烯酰氧基）十八烷-9Z，12Z，15Z-三烯酸（GOPO） 用作治疗炎性疾病如关节炎和骨关节病的口服抗炎药。
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2.发明申请Use of glycosides of mono- and diacylglycerol as anti-inflammatory agents 审中-公开使用单酰基甘油和二酰基甘油的糖苷作为抗炎剂公开(公告)号：US20050049205A1
公开(公告)日：2005-03-03
申请号：US10962664
申请日：2004-10-13
IPC分类号： C07H15/10 , A61K31/00 , A61K31/70 , A61K31/7012 , A61K31/7024 , A61K31/7032 , A61K45/00 , A61P1/04 , A61P1/16 , A61P3/10 , A61P9/10 , A61P17/00 , A61P17/06 , A61P19/02 , A61P25/00 , A61P25/28 , A61P29/00 , A61P31/04 , A61P35/00 , A61P37/06 , A61P37/08 , A61P39/06 , C07H15/04 , C07H15/06
CPC分类号： A61K31/366 , A61K9/48
摘要： Glycosides of diacylglycerol, e.g. 3-β-D-galactopyranosyloxy-2-(octadeca-9Z,12Z,15Z-trienoyloxy)propanyl octadeca-9Z,12Z,15Z-trienoate (GOPO), which was isolated from extracts of rose-hips by activity guided fractionation, can be used as an oral anti-inflammatory agent for the treatment of inflammatory diseases such as arthritis and osteoarthrosis.
摘要翻译： 二酰基甘油的糖苷，例如 可以通过活性引导分馏从玫瑰果提取物中分离出3-β-D-吡喃半乳糖氧基-2-（十八烷-9Z，12Z，15Z-三烯酰氧基）十八烷-9Z，12Z，15Z-三烯酸（GOPO） 用作治疗炎性疾病如关节炎和骨关节病的口服抗炎药。
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