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11 条记录 (耗时 0.029 秒)

    Spatially encoded polymer matrix
    2.
    发明申请
    Spatially encoded polymer matrix 有权
    空间编码聚合物基质

    公开(公告)号：US20060127369A1

    公开(公告)日：2006-06-15

    申请号：US10529397

    申请日：2003-09-26

    申请人： Soren Christensen ,  Jens Truelsen ,  Morten Meldal ,  Roice Michael ,  Ib Johanssen

    发明人： Soren Christensen ,  Jens Truelsen ,  Morten Meldal ,  Roice Michael ,  Ib Johanssen

    IPC分类号： A01N63/00

    CPC分类号： B01J19/0046 ,  B01J2219/005 ,  B01J2219/0054 ,  B01J2219/00551 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00695 ,  B01J2219/00698 ,  B01J2219/00702 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00731 ,  B01J2219/0074

    摘要： The invention relates to a spatially encoded polymer matrix in the form of a bead or a granule for combinatorial solid phase synthesis, assaying, functional proteomics and diagnostic use. Compositions of such beads or granules are also provided. Each beaded polymer matrix of the composition comprises a plurality of spatially immobilised particles. The spatial immobilisation of the particles confers on each beaded polymer matrix a “fingerprint” which enables identification of unique beads in a population of beads. The unique identification of individual beads makes it possible to perform combinatorial chemistry strategies while logging individual chemical transformation. Also provided are methods for detection of relative positions in space of particles, methods for generating matrices, methods for distance matrix determination, methods for identifying individual matrices and devices for recording and storing images of matrices.

    摘要翻译： 本发明涉及用于组合固相合成，测定，功能蛋白质组学和诊断用途的珠粒或颗粒形式的空间编码聚合物基质。 还提供了这种珠粒或颗粒的组合物。 组合物的每个串珠聚合物基质包含多个空间固定的颗粒。 颗粒的空间固定赋予每个珠光聚合物基质上的“指纹”，其使得能够鉴定珠粒群中的独特珠粒。 单个珠的独特鉴定使得在记录单个化学转化的同时执行组合化学策略成为可能。 还提供了用于检测颗粒空间中的相对位置的方法，用于生成矩阵的方法，用于距离矩阵确定的方法，用于识别各个矩阵的方法以及用于记录和存储矩阵的图像的设备。

    Computer-aided generation of programs modelling complex systems using colored petri nets
    4.
    发明授权
    Computer-aided generation of programs modelling complex systems using colored petri nets 失效
    计算机辅助生成使用彩色Petri网建模复杂系统的程序

    公开(公告)号：US5257363A

    公开(公告)日：1993-10-26

    申请号：US507119

    申请日：1990-04-09

    申请人： Robert M. Shapiro ,  Jawahar Malhotra ,  Kurt Jensen ,  Soren Christensen ,  Peter Huber

    发明人： Robert M. Shapiro ,  Jawahar Malhotra ,  Kurt Jensen ,  Soren Christensen ,  Peter Huber

    IPC分类号： G06F17/50 ,  G06F15/20

    CPC分类号： G06F17/5013

    摘要： A method and system in which a programmed digital computer serving as a graphical "engine" is employed to construct an executable model for a complex system using a hierarchy of so called "Colored" Petri nets (CPN's or CP-nets). The operation of the complex system is specified in terms of a graphical net structure and formal net inscriptions, such as arc expressions and guards, which ensure development of a program, or executable model, and associated data structures, properly defining the system. Sophisticated syntax checks and other tools are provided for ensuring that the model so constructed conforms to a set of rules which guarantee valid system behavior.

    摘要翻译： 使用用作图形“引擎”的编程数字计算机的方法和系统用于使用所谓的“彩色”Petri网（CPN或CP网））的层次来为复杂系统构建可执行模型。 复杂系统的操作通过图形网络结构和正式的网络铭文（如弧形表达和守卫）来确定，确保开发程序或可执行模型以及相关的数据结构，正确定义系统。 提供了复杂的语法检查和其他工具，以确保所构建的模型符合一组保证有效系统行为的规则。

    Spherical radiofrequency-encoded beads
    5.
    发明申请
    Spherical radiofrequency-encoded beads 审中-公开
    球形射频编码珠

    公开(公告)号：US20120041111A1

    公开(公告)日：2012-02-16

    申请号：US11631181

    申请日：2005-07-01

    申请人： Soren Christensen ,  Ole Jensen

    发明人： Soren Christensen ,  Ole Jensen

    IPC分类号： C08L33/26 ,  C08K5/1535

    CPC分类号： B01J19/0046 ,  B01J2219/00416 ,  B01J2219/00466 ,  B01J2219/00468 ,  B01J2219/005 ,  B01J2219/00565 ,  B01J2219/00567

    摘要： The invention relates to a method for the production of a composition comprising a plurality of spherical radiofrequency-identifiable (RF-tagged) polymeric beads as well the composition as such. The invention also relates to an apparatus for analyzing, identifying or sorting as well as treating a plurality of spherical radiofrequency-identifiable beads, and further to a method for recording individual reaction steps involved in the step-wise synthesis of a chemical compound on a radiofrequency-detectable bead. The beads of the composition are substantial spherical and preferably comprises a hydrophilic polymer material so as to prevent fouling.

    摘要翻译： 本发明涉及一种制备组合物的方法，所述组合物包含多个球形射频识别（RF标记）聚合物珠粒以及组合物。 本发明还涉及一种用于分析，识别或分选以及处理多个球形射频识别珠的装置，还涉及用于记录在射频上逐步合成化合物的各个反应步骤的方法 可检测珠。 组合物的珠粒是基本上球形的，并且优选包含亲水性聚合物材料，以防止结垢。

    Lipoxygenase
    6.
    发明授权
    Lipoxygenase 失效
    脂氧合酶

    公开(公告)号：US07456001B2

    公开(公告)日：2008-11-25

    申请号：US10362776

    申请日：2001-09-05

    申请人： Soren Christensen ,  Akiko Sugio ,  Shinobu Takagi ,  Lars Ostergaard ,  Ernst Oliw

    发明人： Soren Christensen ,  Akiko Sugio ,  Shinobu Takagi ,  Lars Ostergaard ,  Ernst Oliw

    IPC分类号： C12N9/02 ,  C12N15/00 ,  C12N1/20 ,  C12P21/04 ,  A21D10/00 ,  C11D3/02 ,  C07H21/04 ,  C12Q1/00 ,  C12Q1/68

    CPC分类号： C12N9/0069

    摘要： The invention provides sequence information of a microbial protein having lipoxy-genase activity and a method of producing the protein by recombinant DNA technology. More specifically, the inventors have isolated a gene encoding a lipoxygenase from Gaeu-mannomyces graminis, cloned it into an E. coli strain and sequenced it. A comparison shows less than 25% identity to known lipoxygenase sequences, the closest being human 15S li-poxygenase. The inventors have expressed the lipoxygenase recombinantly and found that the recombinant lipoxygenase is glycosylated.

    摘要翻译： 本发明提供具有脂氧合酶活性的微生物蛋白质的序列信息和通过重组DNA技术生产该蛋白质的方法。 更具体地说，本发明人已经分离出来自禾谷镰刀菌的编码脂氧合酶的基因，将其克隆到大肠杆菌菌株中并对其进行测序。 比较显示与已知的脂氧合酶序列具有小于25％的同一性，最接近的是人15S li-加氧酶。 本发明人重组表达了脂氧合酶，发现重组脂氧合酶被糖基化。

    Charge mode control of a serial resonance converter
    7.
    发明申请
    Charge mode control of a serial resonance converter 有权
    串联谐振变换器的充电模式控制

    公开(公告)号：US20070171679A1

    公开(公告)日：2007-07-26

    申请号：US10595706

    申请日：2004-10-27

    申请人： Runo Nielsen ,  Soren Christensen

    发明人： Runo Nielsen ,  Soren Christensen

    IPC分类号： H02M3/335

    CPC分类号： H02M3/3376 ,  H02M2001/0032 ,  Y02B70/1433 ,  Y02B70/16

    摘要： The present invention relates to an apparatus and a method for converting power from a power input to a DC output current or voltage, where a first feedback circuit a traditional feedback. The converter type is a resonant DC-DC converter. The scope of the invention is to reach a high effective and fast responding switch mode power supply. This can be achieved with an apparatus or method comprising a second feedback circuit leading a signal from a serial resonance capacitor(s) to a reference input terminal at the control circuit, which second feedback circuit contains a signal depending on the actual change in charge of the resonant capacitor(s). This means that at high load, a very powerful signal will be transmitted through the second feedback at the control circuit that will change the operation of the circuit into a charge mode operation. As the load on the output is reduced, the influence of the second feedback signal will be reduced, and the influence from the charge mode is reduced and the operation mode is changing back into a normal frequency mode of operation. In this way, a much more constant gain in the series or series parallel resonant DC-DC converter is achived, and therefore a much better regulated voltage or current of the resonant DC-DC converter can be made.

    摘要翻译： 本发明涉及一种用于将功率从功率输入转换为直流输出电流或电压的装置和方法，其中第一反馈电路是传统反馈。 转换器类型是谐振DC-DC转换器。 本发明的范围是达到高效快速响应的开关电源。 这可以通过包括将来自串联谐振电容器的信号引导到控制电路处的参考输入端子的第二反馈电路的装置或方法来实现，该第二反馈电路包含取决于实际的电荷变化的信号 谐振电容器。 这意味着在高负载下，通过控制电路的第二反馈将传输非常强大的信号，这将使电路的操作改变为充电模式操作。 当输出端的负载减小时，第二反馈信号的影响将被减小，并且充电模式的影响减小，并且操作模式正在变回正常频率工作模式。 以这种方式，串联或串联并联谐振DC-DC转换器的增益更加恒定，因此可以制造出更好的调节电压或谐振DC-DC转换器的电流。