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公开(公告)号：US20130142754A1
公开(公告)日：2013-06-06
申请号：US13492982
申请日：2012-06-11
申请人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
发明人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
CPC分类号： A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/12 , C07D487/04 , C07K5/02 , C07K5/0804
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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2.发明申请公开(公告)号：US20110218185A1
公开(公告)日：2011-09-08
申请号：US13122617
申请日：2009-10-08
IPC分类号： A61K31/53 , C07D487/04 , A61K31/541 , A61P3/04 , A61P3/10
CPC分类号： C07D487/04 , A61K31/53 , A61K31/541
摘要： The present application provides compounds that are useful as MCHR1 antagonists, especially for the treatment of obesity, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I wherein the variables are defined herein.
摘要翻译： 本申请提供了可用作MCHR1拮抗剂的化合物，特别是用于治疗肥胖症，包括根据式I的所有立体异构体，溶剂合物，前药和药学上可接受的形式，其中变量在本文中定义。
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公开(公告)号：US08691757B2
公开(公告)日：2014-04-08
申请号：US13492982
申请日：2012-06-11
申请人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
发明人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
CPC分类号： A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/12 , C07D487/04 , C07K5/02 , C07K5/0804
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US08957203B2
公开(公告)日：2015-02-17
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
IPC分类号： C07D225/00 , C07D295/00 , C07D245/00 , C07D225/04 , C07D487/00 , C07D487/04 , C07K5/083 , C07K5/08 , A61K38/20 , A61K38/21 , A61K45/06 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US08580959B2
公开(公告)日：2013-11-12
申请号：US13122617
申请日：2009-10-08
IPC分类号： C07D487/04 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/14 , A61K31/53 , A61K31/4427 , A61K31/4523 , A61K31/401 , A61P3/04 , A61P3/10
CPC分类号： C07D487/04 , A61K31/53 , A61K31/541
摘要： The present application provides compounds that are useful as MCHR1 antagonists, especially for the treatment of obesity, including all stereoisomers, solvates, prodrugs and pharmaceutically acceptable forms thereof according to Formula I wherein the variables are defined herein.
摘要翻译： 本申请提供了可用作MCHR1拮抗剂的化合物，特别是用于治疗肥胖症，包括根据式I的所有立体异构体，溶剂合物，前药和药学上可接受的形式，其中变量在本文中定义。
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公开(公告)号：US20130115190A1
公开(公告)日：2013-05-09
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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