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公开(公告)号：US08957203B2
公开(公告)日：2015-02-17
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
IPC分类号： C07D225/00 , C07D295/00 , C07D245/00 , C07D225/04 , C07D487/00 , C07D487/04 , C07K5/083 , C07K5/08 , A61K38/20 , A61K38/21 , A61K45/06 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20130115190A1
公开(公告)日：2013-05-09
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：US08691757B2
公开(公告)日：2014-04-08
申请号：US13492982
申请日：2012-06-11
申请人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
发明人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
CPC分类号： A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/12 , C07D487/04 , C07K5/02 , C07K5/0804
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20130142754A1
公开(公告)日：2013-06-06
申请号：US13492982
申请日：2012-06-11
申请人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
发明人： Ramkumar Rajamani , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , Nicholas A. Meanwell , Paul Michael Scola
CPC分类号： A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/208 , A61K38/21 , A61K38/212 , C07D401/12 , C07D487/04 , C07K5/02 , C07K5/0804
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：US07592336B2
公开(公告)日：2009-09-22
申请号：US11430611
申请日：2006-05-09
申请人： Ny Sin , Paul Michael Scola , Nicholas A. Meanwell , Xiangdong Alan Wang , Li-Qiang Sun , Jie Chen , Andrew Charles Good
发明人： Ny Sin , Paul Michael Scola , Nicholas A. Meanwell , Xiangdong Alan Wang , Li-Qiang Sun , Jie Chen , Andrew Charles Good
IPC分类号： A61K31/5377 , A61K31/454 , A61K31/4025 , A61K31/40 , C07D413/10 , C07D401/10 , C07D207/04
CPC分类号： C07K5/0808
摘要： Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20080152619A1
公开(公告)日：2008-06-26
申请号：US11430611
申请日：2006-05-09
申请人： Ny Sin , Paul Michael Scola , Nicholas A. Meanwell , Xiangdong Alan Wang , Li-Qiang Sun , Jie Chen , Andrew Charles Good
发明人： Ny Sin , Paul Michael Scola , Nicholas A. Meanwell , Xiangdong Alan Wang , Li-Qiang Sun , Jie Chen , Andrew Charles Good
IPC分类号： A61K38/20 , C07D207/06 , A61K31/401 , A61P31/14 , A61K38/21
CPC分类号： C07K5/0808
摘要： Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US07763584B2
公开(公告)日：2010-07-27
申请号：US11939768
申请日：2007-11-14
申请人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
发明人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
IPC分类号： A61K38/00
CPC分类号： C07D487/04 , C07D498/04 , C07K5/0812
摘要： Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有以下通式的大环肽。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20080159982A1
公开(公告)日：2008-07-03
申请号：US11939753
申请日：2007-11-14
申请人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
发明人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
IPC分类号： A61K31/407 , C07D487/04 , C07D498/04 , A61K31/7056 , A61K48/00 , A61P31/12 , A61K31/437 , A61K38/20 , A61K38/21 , C07D513/04
CPC分类号： C07D498/04 , C07D487/04 , C07K5/0802 , C07K5/0815
摘要： Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：US08003604B2
公开(公告)日：2011-08-23
申请号：US11939753
申请日：2007-11-14
申请人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
发明人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
IPC分类号： A61K38/00
CPC分类号： C07D498/04 , C07D487/04 , C07K5/0802 , C07K5/0815
摘要： Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有以下通式的大环肽。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20080145334A1
公开(公告)日：2008-06-19
申请号：US11939768
申请日：2007-11-14
申请人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
发明人： Alan Xiangdong Wang , Barbara Zhizhen Zheng , Stanley D'Andrea , Nicholas A. Meanwell , Paul Michael Scola
IPC分类号： A61K31/407 , A61K38/20 , A61K38/48 , A61K38/21 , A61K31/7056 , A61P31/12 , A61K31/437 , A61K38/45 , C07D498/04 , C07D513/04
CPC分类号： C07D487/04 , C07D498/04 , C07K5/0812
摘要： Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有以下通式的大环肽。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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