公开(公告)号：US06548549B1

公开(公告)日：2003-04-15

申请号：US09400655

申请日：1999-09-21

申请人： Thomas Seitz ,  Klaus Naumann ,  Ralf Tiemann ,  Klaus Stenzel ,  Gerd Hänssler ,  Stefan Dutzmann

发明人： Thomas Seitz ,  Klaus Naumann ,  Ralf Tiemann ,  Klaus Stenzel ,  Gerd Hänssler ,  Stefan Dutzmann

IPC分类号： C07D23714

CPC分类号： C07C237/44 ,  C07C235/58 ,  C07C235/62 ,  C07C235/64

摘要： The invention relates to known and to new acylaminosalicylamides, to a plurality of processes for their preparation and to their use as pesticides. The present application furthermore relates to new intermediates, to a plurality of processes for their preparation and to their use as pesticides.

摘要翻译： 本发明涉及已知和新的酰基氨基水杨酰胺，涉及多种制备方法和用作农药的方法。 本申请还涉及新的中间体，涉及多种制备方法和用作杀虫剂的方法。

公开(公告)号：US4699922A

公开(公告)日：1987-10-13

申请号：US873746

申请日：1986-06-12

申请人： Klaus Naumann ,  Rudolf Braden ,  Wolfgang Behrenz ,  Benedikt Becker ,  Bernhard Homeyer ,  Wilhelm Stendel

发明人： Klaus Naumann ,  Rudolf Braden ,  Wolfgang Behrenz ,  Benedikt Becker ,  Bernhard Homeyer ,  Wilhelm Stendel

IPC分类号： C07C313/00 ,  A01N53/00 ,  A01N53/06 ,  C07C67/00 ,  C07C315/04 ,  C07C317/22 ,  C07C323/19 ,  C07C69/74

CPC分类号： A01N53/00

摘要： Pesticidal compositions useful in protecting plants and also in the hygiene field are disclosed. The new tetramethylcyclopropanecarboxylates have the formula ##STR1## where R represents mercapto, methylthio, alkylsulphenyl or alkylsulphonyl.

摘要翻译： 公开了可用于保护植物和卫生领域的杀虫组合物。 新的四甲基环丙烷羧酸酯具有式“IMAGE”，其中R代表巯基，甲硫基，烷基亚磺酰基或烷基磺酰基。

公开(公告)号：US4337352A

公开(公告)日：1982-06-29

申请号：US263812

申请日：1981-05-15

申请人： Klaus Naumann

发明人： Klaus Naumann

IPC分类号： C07B31/00 ,  C07B57/00 ,  C07C51/00 ,  C07C51/487 ,  C07C67/00 ,  C07C313/00 ,  C07C323/55 ,  C07B19/00 ,  C07B21/00

CPC分类号： C07C51/487

摘要： A process for the separation of enantiomers of a chiral carboxylic acid, comprising reacting an alkali metal salt of the acid with an amount of an optically active amine salt which is equivalent to only one enantiomer, in an aqueous weakly alkaline buffered solution as the reaction medium, the reaction medium having a pH value at which the entire acid is present in the ionized form but at which no amine salt is yet deprotonated. Advantageously the carboxylic acid is of the formula ##STR1## wherein R.sup.1 and R.sup.2 each independently is hydrogen, alkyl, with 1-4 C atoms, halogen, optionally substituted phenyl or optionally substituted phenylmercapto,the optically active amine salt is a mineral acid salt of a phenylglycine alkyl ester, .alpha.-methylbenzylamine, phenylethylamine, phenylethanolamine, 1-phenyl-2-dimethyl-amino-1,3-propanediol or abietylamine, the buffered solution contains potassium carbonate, sodium carbonate, sodium bicarbonate or sodium hydrogen phosphate as the buffering agent, and the reaction is effected at about 0.degree. to 100.degree. C., the process including the further steps of separating the precipitated ammonium salt from the alkali metal salt that remains in solution, treating the ammonium salt with a strong acid whereby the free carboxylic acid enantiomer is liberated, and treating the alkali metal salt that remains in solution with a strong acid whereby the free carboxylic enantiomer is liberated.

摘要翻译： 一种用于分离手性羧酸的对映异构体的方法，包括使酸的碱金属盐与一定量的仅相当于一种对映异构体的光学活性胺盐在作为反应介质的弱弱碱性缓冲溶液中反应 反应介质具有pH值，其中整个酸以离子形式存在，但没有胺盐尚未去质子化。 有利地，羧酸具有下式：其中R 1和R 2各自独立地为氢，具有1-4个C原子的烷基，卤素，任选取代的苯基或任选取代的苯基巯基，光学活性胺盐是 苯基甘氨酸烷基酯，α-甲基苄基胺，苯乙基胺，苯基乙醇胺，1-苯基-2-二甲基 - 氨基-1,3-丙二醇或非胺，缓冲溶液含有碳酸钾，碳酸钠，碳酸氢钠或磷酸氢钠作为缓冲剂 该反应在约0℃至100℃下进行，该方法包括进一步的步骤：将沉淀的铵盐与残留在溶液中的碱金属盐分离，用强酸处理铵盐，由此使游离的 释放羧酸对映异构体，并用强酸处理残留在溶液中的碱金属盐，由此游离羧酸对映体被释放 。

公开(公告)号：US4275250A

公开(公告)日：1981-06-23

申请号：US46149

申请日：1979-06-06

申请人： Klaus Naumann ,  Wolfgang Behrenz ,  Ingeborg Hammann ,  Erich Klauke ,  Albrecht Marhold

发明人： Klaus Naumann ,  Wolfgang Behrenz ,  Ingeborg Hammann ,  Erich Klauke ,  Albrecht Marhold

IPC分类号： C07C69/747 ,  A01N53/00 ,  A01N53/06 ,  B01J23/00 ,  B01J31/00 ,  C07B61/00 ,  C07C67/03 ,  C07C67/08 ,  C07C67/10 ,  C07C67/14 ,  C07C33/46

CPC分类号： A01N53/00

摘要： 2,2-Dimethyl-3-vinyl-cyclopropane carboxylic acid esters of halogenated benzyl alcohols of the formula ##STR1## in which each R independently represents F, Cl, Br or CH.sub.3 andm and n each represent 0, 1, 2, 3, 4 or 5 subject to the sum of m+n being not more than 5,with the provisos that(i) when each R represents F or Br then m and n cannot both be 0,(ii) when each R represents Cl, then m represents 0, 1, 2, 3 or 5 and n represents 1, 2, 3, 4 or 5, and(iii) when each R represents CH.sub.3, then m represents 0 and n represents 5,which possess arthropodicidal properties.

摘要翻译： 其中每个R独立地表示F，Cl，Br或CH 3，并且m和n各自表示0,1,2,3或3的卤代苄醇的2,2-二甲基-3-乙烯基 - 环丙烷羧酸酯， ，4或5，m + n的和不大于5，条件是（i）当每个R表示F或Br时，m和n不能都为0，（ii）当每个R表示Cl时， 那么m表示0,1,2,3或5，n表示1,2,3,4或5，（iii）当R表示CH3时，m表示0，n表示5，具有节肢动物学特性。

公开(公告)号：US4236026A

公开(公告)日：1980-11-25

申请号：US970099

申请日：1978-12-15

申请人： Klaus Naumann

发明人： Klaus Naumann

IPC分类号： C07C61/35 ,  C07C51/00 ,  C07C51/487 ,  C07C61/39 ,  C07C61/40 ,  C07C67/00 ,  C07B19/00

CPC分类号： C07C51/487

摘要： A process for the separation of the cis- and trans-stereoisomers of a substituted vinylcyclopropanecarboxylic acid of the formula ##STR1## in which R is alkyl with 1 to 4 carbon atoms, halogen, phenyl or phenyl substituted by at least one of alkyl and halogen, andR.sup.1 is hydrogen, alkyl with 1 to 4 carbon atoms or halogen, orR and R.sup.1, together with the adjacent C atom, form a carbocyclic ring,comprising reacting the free vinylcyclopropanecarboxylic acid in a weakly alkaline aqueous solution with an amount of an amine salt corresponding to the proportion of the cis-isomer present thereby to form a salt precipitate enriched in one of the stereoisomers, separating the precipitant from the supernatant, separately reacting the precipitate and supernatant with a strong acid to liberate the isomeric vinylcyclopropanecarboxylic acid, and recrystallizing at least one of the stereoisomers.

摘要翻译： 分离式为“IMAGE”的取代的乙烯基环丙烷羧酸的顺式和反式立体异构体的方法，其中R是具有1至4个碳原子的烷基，卤素，苯基或被至少一个烷基和卤素取代的苯基 R 1是氢，具有1至4个碳原子的烷基或卤素，或R和R 1与相邻的C原子一起形成碳环，包括使弱碱性水溶液中的游离乙烯基环丙烷羧酸与一定量的 胺盐对应于存在的顺式异构体的比例，从而形成富含一种立体异构体的盐沉淀物，将沉淀剂与上清液分离，分别使沉淀物和上清液与强酸反应以释放异构的乙烯基环丙烷羧酸，以及 使至少一种立体异构体重结晶。

公开(公告)号：US4220663A

公开(公告)日：1980-09-02

申请号：US926586

申请日：1978-07-20

申请人： Andreas Schulze ,  Klaus Sasse ,  Klaus Naumann ,  Peter Roessler ,  Peter Kraus

发明人： Andreas Schulze ,  Klaus Sasse ,  Klaus Naumann ,  Peter Roessler ,  Peter Kraus

IPC分类号： A01N33/10 ,  A01N35/08 ,  C07D307/52 ,  A01N9/20 ,  A01N9/24 ,  C07C93/06

CPC分类号： C07D307/52

摘要： Benzyl phenyl ethers, many of which are new, of the formula ##STR1## in which X is ##STR2## R.sup.1 is H or alkyl, R.sup.2 is alkyl, alkenyl, alkynyl, alkylidene, alkenylidene or alkynylidene optionally substituted by OH, alkoxy, a heterocyclic group containing O, S or N, amino, monoalkylamino, dialkylamino or by an alkylene bridge with 5 carbon atoms,R.sup.3 each independently is H, alkyl, alkoxy, alkylmercapto, halogen, halogenoalkyl, halogenoalkoxy, halogenoalkylmercapto, NO.sub.2, amino, monoalkylamino or dialkylamino,R.sup.4 each independently is H, halogen or alkoxy,m is an integer from 1 to 5, andn is an integer from 1 to 4,and acid addition salts thereof, are useful for combatting arthropods, nematodes, fungi and bacteria.

公开(公告)号：US4196304A

公开(公告)日：1980-04-01

申请号：US883979

申请日：1978-03-06

申请人： Klaus Naumann

发明人： Klaus Naumann

IPC分类号： C07C61/00 ,  C07C51/00 ,  C07C51/487 ,  C07C61/37 ,  C07C61/40 ,  C07C67/00

CPC分类号： C07C51/487

摘要： A process for the separation of the stereoisomers of a stereoisomer mixture of a cyclic carboxylic acid of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently is hydrogen, halogen, C.sub.1 -C.sub.6 -alkyl or C.sub.2 -C.sub.6 -alkenyl,R.sup.3 is alkyl, alkenyl or alkynyl having up to 6 carbon atoms and optionally substituted by halogen, or alkoxycarbonyl having up to 5 carbon atoms, or is aralkyl or aryl, orR.sup.1 plus R.sup.2, or R.sup.1 plus R.sup.3, together with the adjacent C atom, form a carbocyclic ring,R.sup.3 and COOH are cis or trans to one another and the COOH group is in the exo or endo position if R.sup.1 and R.sup.3 together form a ring, andn is 0, 1 or 2,which comprises contacting a weakly alkaline, aqueous solution of the stereoisomeric mixture with a non-polar organic solvent, whereby the cis or endo isomeric free acid enters the organic solvent while the trans or exo isomer remains in the aqueous solution as a salt, and separating the aqueous solution from the organic solvent, thereby to separate the isomers. Preferred acids are cyclopropanecarboxylic acid derivatives, the aqueous solution is preferably buffered to a pH of about 7 to 9 and the organic solvent is preferably a hydrocarbon, halogenated hydrocarbon, aromatic hydrocarbon or ether.

摘要翻译： R 1和R 2各自独立地为氢，卤素，C 1 -C 6烷基或C 2 -C 6 - 烯基的式（I）的环状羧酸的立体异构体混合物的立体异构体的分离方法，R3是烷基 ，具有至多6个碳原子并且任选被卤素取代的链烯基或炔基，或具有至多5个碳原子的烷氧基羰基，或芳基烷基或芳基，或R1 + R2，或R1 + R3与相邻C原子一起形成 碳环，R 3和COOH是顺式或反式的，如果R 1和R 3一起形成环，COOH基团处于外部或内部位置，并且n是0,1或2，其包括使弱碱性水溶液 立体异构体混合物与非极性有机溶剂的溶液，由此顺式或内同异构游离酸进入有机溶剂，同时反式或外型异构体作为盐保留在水溶液中，并将水溶液与有机溶剂分离， 从而分离异构体。 优选的酸是环丙烷羧酸衍生物，水溶液优选缓冲至约7至9的pH，有机溶剂优选为烃，卤代烃，芳族烃或醚。

公开(公告)号：US4183950A

公开(公告)日：1980-01-15

申请号：US844852

申请日：1977-10-25

申请人： Klaus Naumann ,  Wolfgang Behrenz ,  Ingeborg Hammann ,  Erich Klauke ,  Albrecht Marhold

发明人： Klaus Naumann ,  Wolfgang Behrenz ,  Ingeborg Hammann ,  Erich Klauke ,  Albrecht Marhold

IPC分类号： C07C69/747 ,  A01N53/00 ,  A01N53/06 ,  B01J23/00 ,  B01J31/00 ,  C07B61/00 ,  C07C67/03 ,  C07C67/08 ,  C07C67/10 ,  C07C67/14 ,  C07C69/74 ,  A01N9/30

CPC分类号： A01N53/00

摘要： 2,2-Dimethyl-3-vinyl-cyclopropane carboxylic acid esters of halogenated benzyl alcohols of the formula ##STR1## in which each R independently represents F, Cl, Br or CH.sub.3and m and n each represent 0, 1, 2, 3, 4 or 5 subject to the sum of m+n being not more than 5,with the provisos that(i) when each R represents F or Br then m and n cannot both be 0,(ii) when each R represents Cl, then m represents 0, 1, 2, 3 or 4 and n represents 1, 2, 3, 4 or 5, and(iii) when each R represents CH.sub.3, then m represents 0 and n represents 5,which possess arthropodicidal properties.

摘要翻译： 其中每个R独立地表示F，Cl，Br或CH 3，并且m和n各自表示0,1,2,3或3的卤代苄醇的2,2-二甲基-3-乙烯基 - 环丙烷羧酸酯， ，4或5，m + n的和不大于5，条件是（i）当每个R表示F或Br时，m和n不能都为0，（ii）当每个R表示Cl时， 那么m表示0,1,2,3或4，n表示1,2,3,4或5，（iii）当R表示CH3时，m表示0，n表示5，具有节肢动物学特性。

公开(公告)号：US4085646A

公开(公告)日：1978-04-25

申请号：US690557

申请日：1976-05-27

申请人： Klaus Naumann

发明人： Klaus Naumann

IPC分类号： G10H1/00 ,  G10H1/053 ,  G10H5/00 ,  G10H3/02

CPC分类号： G10H5/005

摘要： An electronic musical instrument providing continuous cybernetic tone finding controlled by functions of the human mouth. The instrument includes a mouthpiece into which air is to be blown from the mouth of a player having a measuring apparatus at least partially mounted therein. The measuring apparatus includes an arrangement for producing a pitch determining signal representing a measure of the mouth cavity of the player and a volume determining signal representing the velocity or pressure of the air blown into the mouthpiece. Tone generating apparatus is provided for generating a tone signal whose frequency varies with the level of a control signal applied thereto with a control signal being applied to the tone generating apparatus in accordance with the pitch determining signal and having a level representing a measure of the mouth cavity of the player. Another control signal in accordance with the volume determining signal serves for controlling the output of the tone generating apparatus with the output being converted to sound.

摘要翻译： 一种电子乐器，提供由人嘴功能控制的连续的控制论色调。 仪器包括一个吸嘴，空气从具有至少部分地安装在其中的测量装置的演奏者的嘴部吹出。 该测量装置包括用于产生表示播放器的口腔的度量的音调确定信号的装置和表示吹入到接口管中的空气的速度或压力的音量确定信号。 提供音调发生装置，用于产生音调信号，其频率随施加到其上的控制信号的电平而变化，控制信号根据音调确​​定信号被施加到乐音发生装置，并且具有表示口的测量的音量 球员的腔。 根据音量确定信号的另一个控制信号用于控制音调发生装置的输出，并将输出转换成声音。

公开(公告)号：US4839390A

公开(公告)日：1989-06-13

申请号：US47968

申请日：1987-05-08

申请人： Klaus Naumann ,  Benedikt Becker ,  Wolfgang Behrenz ,  Bernhard Homeyer ,  Wilhelm Stendel

发明人： Klaus Naumann ,  Benedikt Becker ,  Wolfgang Behrenz ,  Bernhard Homeyer ,  Wilhelm Stendel

IPC分类号： A01N29/02 ,  C07C17/00 ,  C07C17/26 ,  C07C21/18 ,  C07C21/19 ,  C07C21/215 ,  C07C21/22 ,  C07C67/00

CPC分类号： C07C17/2635 ,  A01N29/02 ,  C07C17/2637 ,  C07C21/18 ,  C07C21/19 ,  C07C21/215 ,  C07C21/22

摘要： A method of combating arthropods and nematodes which comprises applying thereto, to a habitat thereof or to an area from which they are to be excluded an arthropodicidally or nematocidally effective amount of at least one long-chain halogenoolefine of the formula (I) ##STR1## in which R represents a straight-chain or branched alkyl radical with 8 to 25 carbon atoms in the straight chain, the alkyl radical optionally being interrupted once or several times by a --C.tbd.C-- and/or ##STR2## in which Z and Z.sup.1 are identical or different and represent hydrogen or methyl andR.sup.1 represents hydrogen, alkyl or halogen.Those compounds are new wherein R has at least 12 carbon atoms in the straight chain.

摘要翻译： 一种防治节肢动物和线虫的方法，其包括将其施用于其栖息地或排除其被排除的节肢动物或杀线虫有效量的至少一种式（I）的长链卤代烯烃的区域。 （I）其中R表示在直链中具有8至25个碳原子的直链或支链烷基，所述烷基任选地被-C 3BOND C和/或中断一次或数次 Z和Z 1相同或不同，表示氢或甲基，R 1表示氢，烷基或卤素。 那些化合物是新的，其中R在直链中具有至少12个碳原子。