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公开(公告)号:US4743450A
公开(公告)日:1988-05-10
申请号:US17962
申请日:1987-02-24
申请人: Michael Harris , Gerard Hokanson , Kuchi Murthy , Robert Reisch , Frank Waldman
发明人: Michael Harris , Gerard Hokanson , Kuchi Murthy , Robert Reisch , Frank Waldman
IPC分类号: A61K45/08 , A61K9/20 , A61K31/40 , A61K31/401 , A61K31/445 , A61K38/00 , A61K38/55 , A61K47/00 , A61K47/02 , A61K47/10 , A61K47/26 , A61P43/00 , C07D207/16 , C07D211/32 , A61K31/195 , A61K31/27 , A61K31/505
CPC分类号: A61K31/40 , A61K38/005 , A61K38/556 , A61K47/02 , A61K47/26 , A61K9/2009 , A61K9/2018
摘要: The cyclization, hydrolysis, and coloration of certain ACE inhibitors is minimized when they are formulated with a metal-containing stabilizer and a saccharide.