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    HIGH AFFINITY ANTI-N1,N12-DIACETYLSPERMINE MONOCLONAL ANTIBODY
    3.
    发明申请
    HIGH AFFINITY ANTI-N1,N12-DIACETYLSPERMINE MONOCLONAL ANTIBODY 审中-公开
    高亲和力抗-N1，N12-二乙基蝶呤单克隆抗体

    公开(公告)号：US20100093006A1

    公开(公告)日：2010-04-15

    申请号：US12578322

    申请日：2009-10-13

    申请人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    发明人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    IPC分类号： G01N33/537 ,  C07K16/00 ,  C12N5/16

    CPC分类号： C07K16/30 ,  G01N33/57488

    摘要： The present invention provides an anti-diacetylspermine specific monoclonal antibody which satisfies a specific measuring condition in an immunoreaction system between a solid-phased diacetylspermine and the anti-diacetylspermine specific monoclonal antibody, wherein the immunoreaction system comprises a sample diacetylspermine or sample N1-acetylspermidine to inhibit the immunoreaction; and the specific measuring condition is that the 50% inhibition activity against the immunoreaction by the diacetylspermine in the sample is at least 1,000 times as much as the 50% inhibition activity against the immunoreaction by the N1-acetylspermidine in the sample.

    摘要翻译： 本发明提供一种抗二乙酰精胺特异性单克隆抗体，其在固相化二乙酰精胺与抗二乙酰精胺特异性单克隆抗体之间的免疫反应系统中满足特定测定条件，其中免疫反应系统包含样品二乙酰精胺或样品N1-乙酰精胺 抑制免疫反应; 具体的测定条件是样品中二乙酰精胺的免疫反应的50％抑制活性至少为抗N1样品中N1-乙酰精胺的免疫反应的50％抑制活性的1000倍。

    High affinity anti-N¹,N¹²-diacetylspermine monoclonal antibody
    5.
    发明申请
    High affinity anti-N¹,N¹²-diacetylspermine monoclonal antibody 有权
    高亲和力抗N 1，N 12 - 二乙酰精胺单克隆抗体

    公开(公告)号：US20060166297A1

    公开(公告)日：2006-07-27

    申请号：US11263355

    申请日：2005-10-31

    申请人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    发明人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    IPC分类号： G01N33/537 ,  C07K16/00 ,  C12N5/16 ,  C12N5/06

    CPC分类号： C07K16/30 ,  G01N33/57488

    摘要： The present invention provides an anti-diacetylspermine specific monoclonal antibody which satisfies a specific measuring condition in an immunoreaction system between a solid-phased diacetylspermine and the anti-diacetylspermine specific monoclonal antibody, wherein the immunoreaction system comprises a sample diacetylspermine or sample N1-acetylspermidine to inhibit the immunoreaction; and the specific measuring condition is that the 50% inhibition activity against the immunoreaction by the diacetylspermine in the sample is at least 1,000 times as much as the 50% inhibition activity against the immunoreaction by the N1-acetylspermidine in the sample.

    摘要翻译： 本发明提供一种抗二乙酰精胺特异性单克隆抗体，其在固相二乙酰精胺与抗二乙酰精胺特异性单克隆抗体之间的免疫反应系统中满足特定测定条件，其中免疫反应系统包含样品二乙酰精胺或样品N 1'-乙酰亚精胺抑制免疫反应; 具体的测定条件是，对于样品中的二乙酰精胺的免疫反应的50％抑制活性是抗N0 - 乙酰亚胺的免疫反应的50％抑制活性的至少1000倍 在样品中。

    High affinity anti-N1,N12-diacetylspermine monoclonal antibody
    6.
    发明授权
    High affinity anti-N1,N12-diacetylspermine monoclonal antibody 有权
    高亲和力抗N1，N12-二乙酰精胺单克隆抗体

    公开(公告)号：US07700741B2

    公开(公告)日：2010-04-20

    申请号：US11263355

    申请日：2005-10-31

    申请人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    发明人： Yusei Nagase ,  Shingo Shinagawa ,  Masao Kawakita ,  Kyoko Hiramatsu ,  Mika Ito ,  Yosuke Mizukami ,  Chiemi Minoda

    IPC分类号： C12N15/02

    CPC分类号： C07K16/30 ,  G01N33/57488

    摘要： The present invention provides an anti-diacetylspermine specific monoclonal antibody which satisfies a specific measuring condition in an immunoreaction system between a solid-phased diacetylspermine and the anti-diacetylspermine specific monoclonal antibody, wherein the immunoreaction system comprises a sample diacetylspermine or sample N1-acetylspermidine to inhibit the immunoreaction; and the specific measuring condition is that the 50% inhibition activity against the immunoreaction by the diacetylspermine in the sample is at least 1,000 times as much as the 50% inhibition activity against the immunoreaction by the N1-acetylspermidine in the sample.

    摘要翻译： 本发明提供一种抗二乙酰精胺特异性单克隆抗体，其在固相化二乙酰精胺与抗二乙酰精胺特异性单克隆抗体之间的免疫反应系统中满足特定测定条件，其中免疫反应系统包含样品二乙酰精胺或样品N1-乙酰精胺 抑制免疫反应; 具体的测定条件是样品中二乙酰精胺的免疫反应的50％抑制活性至少为抗N1样品中N1-乙酰精胺的免疫反应的50％抑制活性的1000倍。