公开(公告)号：US20060057234A1

公开(公告)日：2006-03-16

申请号：US11269594

申请日：2005-11-09

申请人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Jai Shankar Arya ,  Ajit Kumar Shasany ,  Monika Singh ,  Soumya Awasthi ,  Subhas Chandra Gupta ,  Mahendra Pandurang Darokar ,  Laiq-Ur Rahman

发明人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Jai Shankar Arya ,  Ajit Kumar Shasany ,  Monika Singh ,  Soumya Awasthi ,  Subhas Chandra Gupta ,  Mahendra Pandurang Darokar ,  Laiq-Ur Rahman

IPC分类号： A61K36/484 ,  A61K31/496 ,  A61K31/4709

CPC分类号： A61K45/06 ,  A61K36/484 ,  A61K2300/00

摘要： The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside ‘glycyrrhizin’ as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.

摘要翻译： 本发明涉及作为植物来源的糖苷“甘草甜素”的非生物碱化合物作为抗生素和其它药物（包括抗感染和抗癌剂）的活性和可获得性的高效生物增强剂的新用途。 本发明的分子有助于植物和动物细胞以及革兰氏阳性和革兰氏阴性菌在细胞膜上吸收/吸收抗生素和其他分子，因此可用作促进剂或生物增殖剂分子以增加感染性 的药物和营养药物。 本身没有抗微生物或细胞毒活性的化合物是减少药物用量以避免耐药性和抗感染和抗癌疗法中的其他副作用的安全候选物。

公开(公告)号：US06979471B1

公开(公告)日：2005-12-27

申请号：US09655710

申请日：2000-09-05

申请人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Jai Shankar Arya ,  Ajit Kumar Shasany ,  Monika Singh ,  Soumya Awasthi ,  Subhas Chandra Gupta ,  Mahendra Pandurang Darokar ,  Laiq Ur Rahman

发明人： Suman Preet Singh Khanuja ,  Sushil Kumar ,  Jai Shankar Arya ,  Ajit Kumar Shasany ,  Monika Singh ,  Soumya Awasthi ,  Subhas Chandra Gupta ,  Mahendra Pandurang Darokar ,  Laiq Ur Rahman

IPC分类号： A61K36/484 ,  A61K45/06 ,  A61K35/78

CPC分类号： A61K45/06 ,  A61K36/484 ,  A61K2300/00

摘要： The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside ‘glycyrrhizin’ as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.

摘要翻译： 本发明涉及作为植物来源的糖苷“甘草甜素”的非生物碱化合物作为抗生素和其它药物（包括抗感染和抗癌剂）的活性和可获得性的高效生物增强剂的新用途。 本发明的分子有助于植物和动物细胞以及革兰氏阳性和革兰氏阴性菌在细胞膜上吸收/吸收抗生素和其他分子，因此可用作促进剂或生物增殖剂分子以增加感染性 的药物和营养药物。 本身没有抗微生物或细胞毒活性的化合物是减少药物用量以避免耐药性和抗感染和抗癌疗法中的其他副作用的安全候选物。

公开(公告)号：USPP20149P2

公开(公告)日：2009-07-07

申请号：US09539992

申请日：2000-03-30

申请人： Gauri Saxena ,  Suchitra Banerjee ,  Laiq ur Rahman ,  Gopal Rao Mallavarapu ,  Srikant Sharma ,  Suman Preet Singh Khanuja ,  Sushil Kumar

发明人： Gauri Saxena ,  Suchitra Banerjee ,  Laiq ur Rahman ,  Gopal Rao Mallavarapu ,  Srikant Sharma ,  Suman Preet Singh Khanuja ,  Sushil Kumar

IPC分类号： A01H5/00

CPC分类号： A01H6/42 ,  A01H5/02 ,  Y02A40/14

摘要： A new and distinct somaclone of rose scented geranium Pelargonium graveolens christened ‘Parimal’ characterized by distinct morphology and improved oil yield determining parameters.

摘要翻译： 玫瑰香薰天竺葵的新鲜而独特的香草天竺葵，被称为“Parimal”，具有不同的形态和改善的油产量决定参数。