公开(公告)号：US08202863B2

公开(公告)日：2012-06-19

申请号：US12062641

申请日：2008-04-04

Applicant: Suzanne C. Aldous ,  John Ziqi Jiang ,  Jinqi Lu ,  Liang Ma ,  Lan Mu ,  Harry Randall Munson ,  Jeffrey Stephen Sabol ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

Inventor： Suzanne C. Aldous ,  John Ziqi Jiang ,  Jinqi Lu ,  Liang Ma ,  Lan Mu ,  Harry Randall Munson ,  Jeffrey Stephen Sabol ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

IPC: C07D239/28 ,  C07D403/12 ,  A61K31/506

CPC classification number: C07D239/28 ,  C07D401/04 ,  C07D403/12 ,  C07D413/04

Abstract: This invention is directed to a compound of formula (I): wherein R1, R2, R3 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).

Abstract translation: 本发明涉及式（I）化合物：其中R1，R2，R3和L1如本文所定义，包含该化合物的药物组合物和该化合物用于治疗过敏和/或炎症性疾病，特别是疾病 如过敏性鼻炎，哮喘和/或慢性阻塞性肺疾病（COPD）。

公开(公告)号：US08258130B2

公开(公告)日：2012-09-04

申请号：US12570355

申请日：2009-09-30

Applicant: Suzanne C Aldous ,  Michael W Fennie ,  John Z Jiang ,  Stanly John ,  Lan Mu ,  Brian Pedgrift ,  James R Pribish ,  Barbara S Rauckman ,  Jeffrey S Sabol ,  Grzegorz T Stoklosa ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

Inventor： Suzanne C Aldous ,  Michael W Fennie ,  John Z Jiang ,  Stanly John ,  Lan Mu ,  Brian Pedgrift ,  James R Pribish ,  Barbara S Rauckman ,  Jeffrey S Sabol ,  Grzegorz T Stoklosa ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

IPC: C07D239/38 ,  C07D403/12 ,  A61K31/506

CPC classification number: C07D239/28 ,  C07D403/12 ,  C07D403/14 ,  C07D413/12 ,  C07D417/14

Abstract: This invention is directed to a compound of formula (I): wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).

Abstract translation: 本发明涉及式（I）化合物：其中R 1，R 2，R 3，R 4和L 1如本文所定义，包含该化合物的药物组合物和该化合物用于治疗过敏和/或炎症性疾病的用途， 尤其是过敏性鼻炎，哮喘和/或慢性阻塞性肺病（COPD）等疾病。

公开(公告)号：USD996239S1

公开(公告)日：2023-08-22

申请号：US29781487

申请日：2021-04-30

Applicant: Lan Mu

Designer： Lan Mu

Abstract: FIG. 1 is a perspective view of a air quality detector showing my new design;
FIG. 2 is a front elevation view thereof;
FIG. 3 is a rear elevation view thereof;
FIG. 4 is a left side elevation view thereof;
FIG. 5 is a right side elevation view thereof;
FIG. 6 is a top plan view thereof; and,
FIG. 7 is a bottom plan view thereof.

公开(公告)号：US20100048568A1

公开(公告)日：2010-02-25

申请号：US12570355

申请日：2009-09-30

Applicant: Suzanne C. Aldous ,  Michael W. Fennie ,  John Z. Jiang ,  Stanly John ,  Lan Mu ,  Brian Pedgrift ,  James R. Pribish ,  Barbara Rauckman ,  Jeffrey S. Sabol ,  Grzegorz T. Stoklosa ,  Sukanthini Thurairatnam ,  Christopher L. Vandeusen

Inventor： Suzanne C. Aldous ,  Michael W. Fennie ,  John Z. Jiang ,  Stanly John ,  Lan Mu ,  Brian Pedgrift ,  James R. Pribish ,  Barbara Rauckman ,  Jeffrey S. Sabol ,  Grzegorz T. Stoklosa ,  Sukanthini Thurairatnam ,  Christopher L. Vandeusen

IPC: A61K31/5377 ,  C07D401/14 ,  A61K31/506 ,  A61P29/00 ,  A61P37/00 ,  A61P37/08 ,  A61P11/06 ,  A61P11/00 ,  C07D403/12 ,  A61K31/496 ,  C07D413/14 ,  A61K31/53 ,  C07D417/14 ,  C07D403/14

CPC classification number: C07D239/28 ,  C07D403/12 ,  C07D403/14 ,  C07D413/12 ,  C07D417/14

Abstract: This invention is directed to a compound of formula (I): wherein R1, R2, R3, R4 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).

Abstract translation: 本发明涉及式（I）化合物：其中R 1，R 2，R 3，R 4和L 1如本文所定义，包含该化合物的药物组合物和该化合物用于治疗过敏和/或炎症性疾病的用途， 尤其是过敏性鼻炎，哮喘和/或慢性阻塞性肺病（COPD）等疾病。

公开(公告)号：US20080227782A1

公开(公告)日：2008-09-18

申请号：US12062641

申请日：2008-04-04

Applicant: Suzanne C. Aldous ,  John Ziqi Jiang ,  Jinqi Lu ,  Liang Ma ,  Lan Mu ,  Harry Randall Munson ,  Jeffrey Stephen Sabol ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

Inventor： Suzanne C. Aldous ,  John Ziqi Jiang ,  Jinqi Lu ,  Liang Ma ,  Lan Mu ,  Harry Randall Munson ,  Jeffrey Stephen Sabol ,  Sukanthini Thurairatnam ,  Christopher Loren Vandeusen

IPC: A61K31/506 ,  A61P11/00 ,  C07D239/28 ,  C07D401/14 ,  C07D403/12 ,  C07D413/12 ,  C07D417/02 ,  A61K31/5377 ,  C07D401/12 ,  C07D401/04 ,  A61K31/505

CPC classification number: C07D239/28 ,  C07D401/04 ,  C07D403/12 ,  C07D413/04

Abstract: This invention is directed to a compound of formula (I): wherein R1, R2, R3 and L1 are as defined herein, a pharmaceutical composition comprising the compound, and the use of the compound to treat allergic and/or inflammatory disorders, particularly disorders such as allergic rhinitis, asthma and/or chronic obstructive pulmonary disease (COPD).

Abstract translation: 本发明涉及式（I）化合物：其中R 1，R 2，R 3和L 1， / SUP>如本文所定义，包含该化合物的药物组合物和该化合物用于治疗过敏性和/或炎症性疾病，特别是诸如过敏性鼻炎，哮喘和/或慢性阻塞性肺病（COPD）的疾病的用途。