公开(公告)号：US08394772B2

公开(公告)日：2013-03-12

申请号：US13395139

申请日：2010-10-20

Applicant: Gregory Raymond Bebernitz ,  Mark Gary Bock ,  Debnath Bhuniya ,  Laxmikant Datrange ,  Suresh Eknath Kurhade ,  P. Venkata Palle ,  Dumbala Srinivas Reddy

Inventor： Gregory Raymond Bebernitz ,  Mark Gary Bock ,  Debnath Bhuniya ,  Laxmikant Datrange ,  Suresh Eknath Kurhade ,  P. Venkata Palle ,  Dumbala Srinivas Reddy

IPC: A01N43/04 ,  A61K31/70 ,  C07H1/00

CPC classification number: C07H17/00 ,  A61K31/351 ,  A61K31/7034 ,  A61K31/7042 ,  A61K31/7056 ,  A61K38/28 ,  A61K45/06 ,  C07D309/10 ,  C07D309/30 ,  C07D405/10 ,  C07D407/10 ,  C07D407/12 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C07D413/10 ,  C07D491/107 ,  C07D493/10 ,  C07D498/04 ,  C07H15/203 ,  C07H15/26 ,  C07H19/04 ,  A61K2300/00

Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

Abstract translation: 本发明涉及由式（I）表示的化合物：其中变量如上文所定义，其可用于治疗D-葡萄糖共转运蛋白（SGLT）介导的疾病和病症，例如， 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。

公开(公告)号：US20120196813A1

公开(公告)日：2012-08-02

申请号：US13395139

申请日：2010-10-20

Applicant: Gregory Raymond Bebernitz ,  Mark Gary Bock ,  Debnath Bhuniya ,  Laxmikant Datrange ,  Suresh Eknath Kurhade ,  P. Venkata Palle ,  Dumbala Srinivas Reddy

Inventor： Gregory Raymond Bebernitz ,  Mark Gary Bock ,  Debnath Bhuniya ,  Laxmikant Datrange ,  Suresh Eknath Kurhade ,  P. Venkata Palle ,  Dumbala Srinivas Reddy

IPC: A61K31/7004 ,  A61K31/352 ,  C07D209/04 ,  A61K31/404 ,  C07H15/20 ,  A61P3/06 ,  A61K31/536 ,  A61P3/10 ,  A61P3/00 ,  A61P3/08 ,  A61P3/04 ,  C07D311/96 ,  C07D265/36

CPC classification number: C07H17/00 ,  A61K31/351 ,  A61K31/7034 ,  A61K31/7042 ,  A61K31/7056 ,  A61K38/28 ,  A61K45/06 ,  C07D309/10 ,  C07D309/30 ,  C07D405/10 ,  C07D407/10 ,  C07D407/12 ,  C07D409/04 ,  C07D409/10 ,  C07D409/12 ,  C07D413/10 ,  C07D491/107 ,  C07D493/10 ,  C07D498/04 ,  C07H15/203 ,  C07H15/26 ,  C07H19/04 ,  A61K2300/00

Abstract: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.

Abstract translation: 本发明涉及由式（I）表示的化合物：其中变量如上文所定义，其可用于治疗D-葡萄糖共转运蛋白（SGLT）介导的疾病和病症，例如， 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。