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公开(公告)号:US20090170886A1
公开(公告)日:2009-07-02
申请号:US11997983
申请日:2006-07-07
申请人: Mark Laurence Boys , Michelle Marie Bruendl , Victoria Leigh Downs , Stephen Alan Fakhoury , William Glen Harter , Lain-Yen Hu , Sandra Marie Jennings , Bruce Allen Lefker , Lorna Helen Mitchell , Raj Kumar Raheja , Yvonne Dorothy Smith
发明人: Mark Laurence Boys , Michelle Marie Bruendl , Victoria Leigh Downs , Stephen Alan Fakhoury , William Glen Harter , Lain-Yen Hu , Sandra Marie Jennings , Bruce Allen Lefker , Lorna Helen Mitchell , Raj Kumar Raheja , Yvonne Dorothy Smith
IPC分类号: A61K31/435 , C07C43/20 , C07D213/02 , A61P35/00 , A61K31/08
CPC分类号: C07C255/54 , C07C2601/02 , C07D213/30 , C07D213/64 , C07D213/65 , C07D309/12 , C07D319/20
摘要: The present invention is directed to a new class of benzonitriles and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of these compounds to decrease excess sebum secretions and to stimulate hair growth.
摘要翻译: 本发明涉及一类新的苯腈和它们作为雄激素受体调节剂的用途。 本发明的其它方面涉及这些化合物用于减少过量的皮脂分泌和刺激毛发生长的用途。
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公开(公告)号:US20090131397A1
公开(公告)日:2009-05-21
申请号:US12262565
申请日:2008-10-31
申请人: Simon Bailey , Stephen Douglas Barrett , Larry Don Bratton , Stephen Alan Fakhoury , Sandra Marie Jennings , Lorna Helen Mitchell , Raj Kumar Raheja , Veerabahu Shanmugasundaram
发明人: Simon Bailey , Stephen Douglas Barrett , Larry Don Bratton , Stephen Alan Fakhoury , Sandra Marie Jennings , Lorna Helen Mitchell , Raj Kumar Raheja , Veerabahu Shanmugasundaram
IPC分类号: A61K31/397 , C07D261/06 , A61K31/42 , C07D413/02 , A61K31/4439 , A61K31/496 , A61P17/00 , A61K31/5377 , C07D417/02 , A61K31/541 , C07D487/12 , A61K31/506
CPC分类号: C07D261/08 , C07D261/18 , C07D413/08 , C07D413/12 , C07D413/14 , C07D417/08 , C07D471/04
摘要: The present application is directed to a new class of isoxazoles and their use as estrogen modulators.
摘要翻译: 本申请涉及一类新的异恶唑及其作为雌激素调节剂的用途。
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公开(公告)号:US07094798B1
公开(公告)日:2006-08-22
申请号:US10424228
申请日:2003-04-25
申请人: Richard John Booth , Ellen Myra Dobrusin , Alan Kraker , Lorna Helen Mitchell , William Alexander Denny , Jeffrey Bruce Smaill , Andrew Mark Thompson , Florence Oliver Joseph McCarthy , Ho Huat Lee , Brian Desmond Palmer
发明人: Richard John Booth , Ellen Myra Dobrusin , Alan Kraker , Lorna Helen Mitchell , William Alexander Denny , Jeffrey Bruce Smaill , Andrew Mark Thompson , Florence Oliver Joseph McCarthy , Ho Huat Lee , Brian Desmond Palmer
IPC分类号: A61K31/403 , C07D209/88
CPC分类号: C07D487/04 , C07D209/88 , C07D491/04
摘要: This invention relates to pyrrolocarbazole derivatives according formula I wherein R1, R2, R7, R8, R9, X and Y are as defined in the specification wherein said derivatives specifically inhibit one or both of the checkpoint kinases Wee1 and Chk1
摘要翻译: 本发明涉及式I的吡咯并咔唑衍生物,其中R 1,R 2,R 7,R 8, R 9,X和Y如说明书中所定义,其中所述衍生物特异性抑制检查点激酶Wee1和Chk1中的一个或两个
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