公开(公告)号：US20060040258A1

公开(公告)日：2006-02-23

申请号：US10924738

申请日：2004-08-23

申请人： Huiyan Guo ,  Lorraine Bautista ,  Zurong Wu ,  Jinn-nan Lin

发明人： Huiyan Guo ,  Lorraine Bautista ,  Zurong Wu ,  Jinn-nan Lin

IPC分类号： C12Q1/70 ,  G01N33/53 ,  G01N33/554 ,  G01N33/569

CPC分类号： G01N33/532

摘要： The present invention provides water-soluble conjugates and methods of using them in diagnostic and detection assays. Devices for performing detection and quantitation assays are also provided. In various embodiments the conjugates are useful in immunoassays and later flow assays. The invention also provides methods of preparing the conjugates that result in higher yields and higher sensitivities for the assays.

摘要翻译： 本发明提供水溶性缀合物及其在诊断和检测测定中的使用方法。 还提供了用于进行检测和定量测定的装置。 在各种实施方案中，缀合物可用于免疫测定和随后的流式测定。 本发明还提供了制备结合物的方法，其导致更高的产率和更高的敏感性。

公开(公告)号：US20120109011A1

公开(公告)日：2012-05-03

申请号：US13284748

申请日：2011-10-28

申请人： Lorraine Cogan ,  Mary Catherine Parsons ,  Christopher Tarpey ,  Lorraine Bautista ,  Martin Bouliane ,  John Zeis ,  Steve Vorres

发明人： Lorraine Cogan ,  Mary Catherine Parsons ,  Christopher Tarpey ,  Lorraine Bautista ,  Martin Bouliane ,  John Zeis ,  Steve Vorres

IPC分类号： A61B5/00

CPC分类号： A61B10/0045 ,  A61B10/0051

摘要： The present invention provides a sample collection device for determining that an adequate amount of sample is collected, the sample collection device including a sample collection member for collecting a fluid sample and at least one electrode, the at least one electrode being in liquid communication with the sample collection member and including a processor. In one embodiment, the sample collection member includes a groove structure, wherein at least one electrode is located on each side of the groove.

摘要翻译： 本发明提供了一种用于确定收集足够量的样品的样品收集装置，所述样品收集装置包括用于收集流体样品的样品收集构件和至少一个电极，所述至少一个电极与 样品收集构件并包括处理器。 在一个实施例中，样品收集构件包括凹槽结构，其中至少一个电极位于凹槽的每一侧上。

公开(公告)号：US06565808B2

公开(公告)日：2003-05-20

申请号：US09860408

申请日：2001-05-18

申请人： Robert Thomas Hudak ,  Lorraine Bautista

发明人： Robert Thomas Hudak ,  Lorraine Bautista

IPC分类号： G01N3348

CPC分类号： B01L3/5023 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2300/0672 ,  B01L2300/0825 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2400/0406 ,  B01L2400/0644 ,  B01L2400/0677 ,  B01L2400/0683 ,  Y10T436/25375 ,  Y10T436/255

摘要： The present invention recognizes that it can be desirable to have a sample receiving chamber integral to or engageable with a test platform, such as a test platform that includes a test strip. The sample receiving chamber is preferably separate or separable from the test platform, but that need not be the case. Preferably, a fluid flow actuating device or structure, such as a valve separates the sample receiving chamber from the test platform. A first aspect of the present invention is a test device that includes a sample receiving chamber and a test platform that preferably includes a test element. A second aspect of the present invention is a method of detecting an analyte in a sample, including: providing a sample, contacting the sample with a test device and detecting the analyte in the sample.

摘要翻译： 本发明认识到，可能需要使样本接收室与测试平台（例如包括测试条）的测试平台成一体或与其接合。 样品接收室优选与测试平台分离或分离，但不一定是这种情况。 优选地，诸如阀之类的流体流动致动装置或结构将样品接收室与测试平台分开。 本发明的第一方面是一种测试装置，其包括样品接收室和优选包括测试元件的测试平台。 本发明的第二方面是检测样品中的分析物的方法，包括：提供样品，使样品与测试装置接触并检测样品中的分析物。

公开(公告)号：US06890484B2

公开(公告)日：2005-05-10

申请号：US10278686

申请日：2002-10-22

申请人： Lorraine Bautista ,  Zhumin Guan

发明人： Lorraine Bautista ,  Zhumin Guan

IPC分类号： B01L3/00 ,  G01N33/48

CPC分类号： B01L3/5023 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2300/0672 ,  B01L2300/0825 ,  B01L2300/0864 ,  B01L2300/087 ,  B01L2400/0406 ,  B01L2400/0644 ,  B01L2400/0677 ,  B01L2400/0683 ,  Y10T436/25375 ,  Y10T436/255

摘要： The present invention recognizes that it can be desirable to have a sample receiving chamber integral to or engageable with a test platform, such as a test platform that includes a test strip. The sample receiving chamber is preferably separate or separable from the test platform, but that need not be the case. Preferably, a fluid flow actuating device or structure, such as a valve separates the sample receiving chamber from the test platform. The present invention provides such a device and methods of use. A first aspect of the present invention is a test device that includes a sample receiving chamber and a test platform that preferably includes a test element. The sample receiving chamber preferably engages the test platform and is optionally separable therefrom. A second aspect of the present invention is a method of detecting an analyte in a sample, including: providing a sample, contacting the sample with a test device and detecting the analyte in the sample. The test device preferably includes a sample receiving chamber and a test platform that includes a test element. Preferably, the sample receiving chamber engages the test platform and optionally the sample receiving chamber is separable from the test platform.

摘要翻译： 本发明认识到，可能需要使样本接收室与测试平台（例如包括测试条）的测试平台成一体或与其接合。 样品接收室优选与测试平台分离或分离，但不一定是这种情况。 优选地，诸如阀之类的流体流动致动装置或结构将样品接收室与测试平台分开。 本发明提供了这样的装置和使用方法。 本发明的第一方面是一种测试装置，其包括样品接收室和优选包括测试元件的测试平台。 样品接收室优选地接合测试平台并且可选地与其分离。 本发明的第二方面是检测样品中的分析物的方法，包括：提供样品，使样品与测试装置接触并检测样品中的分析物。 测试装置优选地包括样本接收室和包括测试元件的测试平台。 优选地，样品接收室接合测试平台，并且可选地，样品接收室可与测试平台分离。