公开(公告)号：US20110295200A1

公开(公告)日：2011-12-01

申请号：US13143703

申请日：2010-01-08

申请人： Ulrich Speck ,  Silvio Schaffner ,  Magdalena Renke-gluszko

发明人： Ulrich Speck ,  Silvio Schaffner ,  Magdalena Renke-gluszko

IPC分类号： A61M25/10 ,  B65B1/04 ,  B05C13/02 ,  A61M29/00 ,  B05C11/00

CPC分类号： A61L29/16 ,  A61L29/06 ,  A61L2300/216 ,  A61L2300/416 ,  A61L2300/602 ,  A61L2300/63 ,  A61M25/1002 ,  A61M25/1029 ,  A61M2025/1004 ,  A61M2025/1031 ,  A61M2025/105 ,  C08L77/00

摘要： The present invention relates to a drug-eluting medical device, in particular a balloon for angioplasty catheters with drug elution to prevent the restenosis of the vessel subjected to angioplasty. More particularly, the present invention relates to a catheter balloon completely or partially coated with paclitaxel in hydrated crystalline form or in hydrated solvated crystalline form, having an immediate release and bioavailability of a therapeutically effective amount of paclitaxel at the site of intervention. The balloon can be made of a polyether-polyamide block copolymer, or a polyester amide, or polyamide-12.

摘要翻译： 本发明涉及一种药物洗脱医学装置，特别是用于血管成形术导管的气囊，其具有药物洗脱以防止经血管成形术的血管的再狭窄。 更具体地说，本发明涉及完全或部分地涂覆有水合结晶形式的紫杉醇或水合溶剂化晶体形式的导管球囊，其在干预部位具有治疗有效量的紫杉醇的即时释放和生物利用度。 气球可以由聚醚 - 聚酰胺嵌段共聚物或聚酯酰胺或聚酰胺-12制成。