公开(公告)号：US20050153056A1

公开(公告)日：2005-07-14

申请号：US11076391

申请日：2005-03-09

申请人： Lynn Winterton ,  Yongxing Qiu ,  John Lally ,  Manal Gabriel

发明人： Lynn Winterton ,  Yongxing Qiu ,  John Lally ,  Manal Gabriel

IPC分类号： A61L27/34 ,  A61L31/10 ,  G02B1/04 ,  B05D3/00 ,  A61L2/00

CPC分类号： G02B1/043 ,  A61L27/34 ,  A61L31/10 ,  A61L2400/10 ,  Y10T428/31667 ,  Y10T428/31884 ,  Y10T428/31891 ,  Y10T428/31935 ,  Y10T428/31971

摘要： The present invention provides a medical device, preferably an ophthalmic device, more preferably a contact lens, which comprises a lubricious coating including a capping layer of polyvinylpyrrolidone and/or at least one layer of a lubricious coating material and one layer of a polyionic material having charges opposite of the charges of the lubricious coating material. The lubricious coating on the medical device of the invention has increased lubricity, preferably characterized by an averaged CoF of about 3.0 or less, increased hydrophilicity characterized by an averaged contact angle of about 80 degree or less, and increased bacterial adhesion resistance, while maintaining the desired bulk properties such as oxygen permeability and ion permeability of lens material. Such lenses are useful as extended-wear contact lenses. In addition, the invention provides a method for making a medical device, preferably a contact lens, having a lubricious coating thereon.

摘要翻译： 本发明提供了一种医疗装置，优选眼科装置，更优选隐形眼镜，其包括含有聚乙烯吡咯烷酮的覆盖层和/或至少一层光滑涂层材料和一层聚离子材料的光滑涂层， 电荷与润滑涂层材料的电荷相反。 本发明的医疗装置上的润滑涂层具有增加的润滑性，优选特征在于平均CoF为约3.0或更小，增加的亲水性特征在于平均接触角为约80度或更小，并且增加了细菌粘附性，同时保持 所需的体积特性如透氧性和透镜材料的离子渗透性。 这种透镜可用作延长佩戴的隐形眼镜。 此外，本发明提供了制造其上具有光滑涂层的医疗装置，优选隐形眼镜的方法。