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公开(公告)号:US4668661A
公开(公告)日:1987-05-26
申请号:US664064
申请日:1984-10-23
IPC分类号: A61K35/74 , A61K38/00 , A61P25/20 , C07K9/00 , C07K14/005 , C07K14/195 , C07K14/41 , C12P21/02 , A61K37/02
摘要: A compound capable of inducing sleep in mammals comprising a peptidoglycan monomer obtained by lysozyme digestion of linear non-crosslinked peptidoglycan polymer chains present in culture fluids of penicillin-treated Brevibacterium divaricatum mutant NRRL 2311 together with hydrolysis of at least one amide group of said monomer.
摘要翻译: 一种能够在哺乳动物中诱导睡眠的化合物,其包含通过溶菌酶消化而获得的肽聚糖单体,所述肽聚糖链存在于青霉素处理的黑曲霉突变体NRRL 2311的培养液中以及至少一种所述单体的酰胺基团的水解。