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公开(公告)号：US08623986B2
公开(公告)日：2014-01-07
申请号：US12226508
申请日：2007-04-19
CPC分类号： C08G77/38 , A61K31/695 , A61L27/18 , A61L27/52 , A61L2400/06 , C08G18/10 , C08G18/61 , C08G18/8108 , C08G77/14 , C08G77/16 , C08G77/18 , C08G77/20 , C08G77/26 , C08G77/388 , C08G77/46 , C08G2220/00 , C08L83/04
摘要： The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.
摘要翻译： 本发明涉及生物稳定凝胶，其包含：（a）至少一种含硅多元醇，多胺，聚环氧或多异氰酸酯，其具有一个或多个官能团，分子量至少为20,000，其在以下存在下固化：（b） 至少一种分子量小于10,000的二醇，二胺或二异氰酸酯; 和/或（c）引发剂，其制备方法及其在制造和修复生物材料和医疗装置，制品或植入物中的用途，特别是软组织植入物的制造，例如乳房植入物和修复矫形关节 如脊椎盘。
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公开(公告)号：US08207245B2
公开(公告)日：2012-06-26
申请号：US11663870
申请日：2005-09-28
IPC分类号： A61F2/00 , C08F283/12 , C08G18/61 , C08G77/452 , C08G77/14 , C08G77/458
CPC分类号： C08G77/46 , A61L27/18 , A61L27/52 , C07F7/0838 , C08G18/283 , C08G18/3284 , C08G18/61 , C08G77/442 , C08G77/445 , C08G77/458 , C08L83/04
摘要： The present invention relates to silicon-containing biostable gels and processes for their preparation. The gels possess properties which make them useful in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of soft tissue implants such as breast implants and the repair of orthopaedic joints such as spinal discs.
摘要翻译： 本发明涉及含硅生物稳定凝胶及其制备方法。 凝胶具有使其在生物材料和医疗装置，制品或植入物的制造和修复中有用的特性，特别是制造软组织植入物例如乳房植入物以及修复诸如脊椎盘的矫形关节。
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公开(公告)号：US20080293844A1
公开(公告)日：2008-11-27
申请号：US11663870
申请日：2005-09-28
CPC分类号： C08G77/46 , A61L27/18 , A61L27/52 , C07F7/0838 , C08G18/283 , C08G18/3284 , C08G18/61 , C08G77/442 , C08G77/445 , C08G77/458 , C08L83/04
摘要： The present invention relates to silicon-containing biostable gels and processes for their preparation. The gels possess properties which make them useful in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of soft tissue implants such as breast implants and the repair of orthopaedic joints such as spinal discs.
摘要翻译： 本发明涉及含硅生物稳定凝胶及其制备方法。 凝胶具有使其在生物材料和医疗装置，制品或植入物的制造和修复中有用的特性，特别是制造软组织植入物例如乳房植入物以及修复诸如脊椎盘的矫形关节。
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公开(公告)号：US20100029802A1
公开(公告)日：2010-02-04
申请号：US12226508
申请日：2007-04-19
CPC分类号： C08G77/38 , A61K31/695 , A61L27/18 , A61L27/52 , A61L2400/06 , C08G18/10 , C08G18/61 , C08G18/8108 , C08G77/14 , C08G77/16 , C08G77/18 , C08G77/20 , C08G77/26 , C08G77/388 , C08G77/46 , C08G2220/00 , C08L83/04
摘要： The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of asoft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.
摘要翻译： 本发明涉及生物稳定凝胶，其包含：（a）至少一种含硅多元醇，多胺，聚环氧或多异氰酸酯，其具有一个或多个官能团，分子量至少为20,000，其在以下存在下固化：（b） 至少一种分子量小于10,000的二醇，二胺或二异氰酸酯; 和/或（c）引发剂，其制备方法及其在制造和修复生物材料和医疗装置，制品或植入物中的用途，特别是软骨组织植入物如乳房植入物的制造和矫形关节的修复 作为脊椎盘。
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公开(公告)号：US20140323676A1
公开(公告)日：2014-10-30
申请号：US14148044
申请日：2014-01-06
IPC分类号： C08G77/38 , C08G77/388
CPC分类号： C08G77/38 , A61K31/695 , A61L27/18 , A61L27/52 , A61L2400/06 , C08G18/10 , C08G18/61 , C08G18/8108 , C08G77/14 , C08G77/16 , C08G77/18 , C08G77/20 , C08G77/26 , C08G77/388 , C08G77/46 , C08G2220/00 , C08L83/04
摘要： The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.
摘要翻译： 本发明涉及生物稳定凝胶，其包含：（a）至少一种含硅多元醇，多胺，聚环氧或多异氰酸酯，其具有一个或多个官能团，分子量至少为20,000，其在以下存在下固化：（b） 至少一种分子量小于10,000的二醇，二胺或二异氰酸酯; 和/或（c）引发剂，其制备方法及其在制造和修复生物材料和医疗装置，制品或植入物中的用途，特别是软组织植入物的制造，例如乳房植入物和修复矫形关节 如脊椎盘。
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