Method for purifying L-cysteine
    1.
    发明授权
    Method for purifying L-cysteine 有权
    L-半胱氨酸的纯化方法

    公开(公告)号:US09120729B2

    公开(公告)日:2015-09-01

    申请号:US14110755

    申请日:2012-04-19

    IPC分类号: C07C227/00 C07C319/28

    CPC分类号: C07C319/28 C07C323/58

    摘要: The invention relates to a method for producing a purified solution containing L-cysteine from a fermentation broth containing L-cysteine. In said method, the fermentation broth containing L-cysteine, at a pH value from pH 6 to 9, is brought in contact with a basic anion exchanger, wherein the L-cysteine bonds to the anion exchanger. The anion exchanger is then rinsed with a first washing solution, and the bonded L-cysteine is removed from the anion exchanger by means of an acid and transferred into an eluate. Said eluate, having a pH≦4, is brought in contact with an acidic cation exchanger, wherein the L-cysteine bonds to the cation exchanger. The cation exchanger is rinsed with a second washing solution, and the bonded L-cysteine is removed from the cation exchanger by means of a strong acid.

    摘要翻译: 本发明涉及从含有L-半胱氨酸的发酵液制备含有L-半胱氨酸的纯化溶液的方法。 在所述方法中,将含有L-半胱氨酸的发酵液pH值从pH6至9与碱性阴离子交换剂接触,其中L-半胱氨酸与阴离子交换剂键合。 然后将阴离子交换剂用第一洗涤溶液冲洗,并通过酸从阴离子交换器中除去键合的L-半胱氨酸并转移到洗脱液中。 所述具有pH≦̸ 4的洗脱液与酸性阳离子交换剂接触,其中L-半胱氨酸与阳离子交换剂键合。 阳离子交换剂用第二洗涤溶液冲洗,并通过强酸从阳离子交换器中除去键合的L-半胱氨酸。

    METHOD FOR PURIFYING L-CYSTEINE
    4.
    发明申请
    METHOD FOR PURIFYING L-CYSTEINE 有权
    纯化L-酪氨酸的方法

    公开(公告)号:US20140031586A1

    公开(公告)日:2014-01-30

    申请号:US14110755

    申请日:2012-04-19

    IPC分类号: C07C319/28

    CPC分类号: C07C319/28 C07C323/58

    摘要: The invention relates to a method for producing a purified solution containing L-cysteine from a fermentation broth containing L-cysteine. In said method, the fermentation broth containing L-cysteine, at a pH value from pH 6 to 9, is brought in contact with a basic anion exchanger, wherein the L-cysteine bonds to the anion exchanger. The anion exchanger is then rinsed with a first washing solution, and the bonded L-cysteine is removed from the anion exchanger by means of an acid and transferred into an eluate. Said eluate, having a pH≦4, is brought in contact with an acidic cation exchanger, wherein the L-cysteine bonds to the cation exchanger. The cation exchanger is rinsed with a second washing solution, and the bonded L-cysteine is removed from the cation exchanger by means of a strong acid.

    摘要翻译: 本发明涉及从含有L-半胱氨酸的发酵液制备含有L-半胱氨酸的纯化溶液的方法。 在所述方法中,将含有L-半胱氨酸的发酵液pH值从pH6至9与碱性阴离子交换剂接触,其中L-半胱氨酸与阴离子交换剂键合。 然后将阴离子交换剂用第一洗涤溶液冲洗,并通过酸从阴离子交换器中除去键合的L-半胱氨酸并转移到洗脱液中。 所述具有pH @ 4的洗脱液与酸性阳离子交换剂接触,其中L-半胱氨酸与阳离子交换剂键合。 阳离子交换剂用第二洗涤溶液冲洗,并通过强酸从阳离子交换器中除去键合的L-半胱氨酸。