公开(公告)号：US06699170B1

公开(公告)日：2004-03-02

申请号：US09688396

申请日：2000-10-16

申请人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

发明人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

IPC分类号： A61N500

CPC分类号： A61N5/1002 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1075 ,  A61N2005/1004 ,  A61N2005/1005

摘要： Disclosed is a balloon catheter having an inflatable balloon having a radiation carrier such as a radiation delivery layer thereon. In one embodiment, the radiation delivery layer comprises one or more layers of metal foil, such as gold. The foil is irradiated, and the balloon is thereafter positioned at a treatment site in a vessel and expanded to bring the metal foil layer into close proximity with the vessel wall. In another embodiment, the radiation carrier is in the form of a dopant in the balloon material. Methods of using the balloon include radiation dosing a site following a balloon dilatation or other procedure, and simultaneously performing balloon angioplasty and radiation dosing.

摘要翻译： 公开了一种气球导管，其具有可膨胀气囊，其上具有辐射载体，例如辐射传送层。 在一个实施例中，辐射传送层包括一层或多层金属箔，例如金。 照射箔，然后将球囊定位在容器中的处理部位并膨胀以使金属箔层与容器壁紧密接近。 在另一个实施例中，辐射载体在球囊材料中是掺杂剂的形式。 使用球囊的方法包括对球囊扩张或其它手术后的部位进行辐射给药，同时进行球囊血管成形术和放射剂量。

公开(公告)号：US06176821B1

公开(公告)日：2001-01-23

申请号：US09119828

申请日：1998-07-21

申请人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

发明人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

IPC分类号： A61N500

CPC分类号： A61N5/1002 ,  A61M25/10 ,  A61M25/1002 ,  A61M2025/1075 ,  A61N2005/1004 ,  A61N2005/1005

摘要： Disclosed is a balloon catheter having an inflatable balloon having a radiation carrier such as a radiation delivery layer thereon. In one embodiment, the radiation delivery layer comprises one or more layers of metal foil, such as gold. The foil is irradiated, and the balloon is thereafter positioned at a treatment site in a vessel and expanded to bring the metal foil layer into close proximity with the vessel wall. In another embodiment, the radiation carrier is in the form of a dopant in the balloon material. Methods of using the balloon include radiation dosing a site following a balloon dilatation or other procedure, and simultaneously performing balloon angioplasty and radiation dosing.

摘要翻译： 公开了一种气球导管，其具有可膨胀气囊，其上具有辐射载体，例如辐射传送层。 在一个实施例中，辐射传送层包括一层或多层金属箔，例如金。 照射箔，然后将球囊定位在容器中的处理部位并膨胀以使金属箔层与容器壁紧密接近。 在另一个实施例中，辐射载体在球囊材料中是掺杂剂的形式。 使用球囊的方法包括对球囊扩张或其它手术后的部位进行辐射给药，同时进行球囊血管成形术和放射剂量。

公开(公告)号：US5782742A

公开(公告)日：1998-07-21

申请号：US789969

申请日：1997-01-31

申请人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

发明人： Michael Crocker ,  George F. Kick ,  Mark A. Siminuk

IPC分类号： A61M25/00 ,  A61F2/958 ,  A61M36/04 ,  A61N5/10 ,  C04B28/02 ,  A61M29/02 ,  A61M36/12

CPC分类号： A61N5/1002 ,  A61M2025/1075 ,  A61M25/10 ,  A61M25/1002 ,  A61N2005/1004 ,  A61N2005/1005

摘要： Disclosed is a balloon catheter having an inflatable balloon having a radiation carrier such as a radiation delivery layer thereon. In one embodiment, the radiation delivery layer comprises one or more layers of metal foil, such as gold. The foil is irradiated, and the balloon is thereafter positioned at a treatment site in a vessel and expanded to bring the metal foil layer into close proximity with the vessel wall. In another embodiment, the radiation carrier is in the form of a dopant in the balloon material. Methods of using the balloon include radiation dosing a site following a balloon dilatation or other procedure, and simultaneously performing balloon angioplasty and radiation dosing.

摘要翻译： 公开了一种气球导管，其具有可膨胀气囊，其上具有辐射载体，例如辐射传送层。 在一个实施例中，辐射传送层包括一层或多层金属箔，例如金。 照射箔，然后将球囊定位在容器中的处理部位并膨胀以使金属箔层与容器壁紧密接近。 在另一个实施例中，辐射载体在球囊材料中是掺杂剂的形式。 使用球囊的方法包括对球囊扩张或其它手术后的部位进行辐射给药，同时进行球囊血管成形术和放射剂量。