公开(公告)号：US20070049528A1

公开(公告)日：2007-03-01

申请号：US11551337

申请日：2006-10-20

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K38/17 ,  C07K14/715

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

公开(公告)号：US20070049527A1

公开(公告)日：2007-03-01

申请号：US11551328

申请日：2006-10-20

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K38/17 ,  C07K14/715 ,  C07H21/04 ,  C12P21/06

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor17，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor17的多核苷酸位于染色体5上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

公开(公告)号：US20070141051A1

公开(公告)日：2007-06-21

申请号：US11552238

申请日：2006-10-24

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K39/395 ,  C07K16/28

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

公开(公告)号：US20070044209A1

公开(公告)日：2007-03-01

申请号：US11216156

申请日：2005-09-01

申请人： Mark Maurer

发明人： Mark Maurer

IPC分类号： A41B9/02

CPC分类号： A41B9/023 ,  A61F5/40

摘要： The genital support device is a device for comfortably supporting male genitalia. The device may be incorporated in briefs or may be worn as a separate piece. The device includes a hammock-like structure having pouches to house the testicles therein. A front wall of the structure is V-shaped to allow the penis to be positioned thereover. A soft lining is disposed adjacent the pouches to afford comfortable protection for the scrotum area. Plural straps extend from the hammock for attaching the device to a pair of briefs or to an elastic waistband.

摘要翻译： 生殖器支持装置是用于舒适地支撑男性生殖器的装置。 该装置可以并入内裤或可以作为单独的部件穿着。 该装置包括具有用于容纳睾丸的小袋的吊床状结构。 结构的前壁是V形的，以允许阴茎定位在其上。 在衬袋附近设置柔软的衬里以为阴囊区域提供舒适的保护。 多个吊带从吊床延伸，用于将设备连接到一对三角裤或弹性腰带。

公开(公告)号：US20050214801A1

公开(公告)日：2005-09-29

申请号：US10982555

申请日：2004-11-05

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： C07K14/715 ,  C12Q1/68 ,  C07H21/04 ,  C12N15/09

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor17，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor17的多核苷酸位于染色体5上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

公开(公告)号：US20070105777A1

公开(公告)日：2007-05-10

申请号：US11620994

申请日：2007-01-08

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K38/17 ,  C07K14/715 ,  C07H21/04 ,  C12P21/06

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytorl7, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor17，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor17的多核苷酸位于染色体5上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

公开(公告)号：US20070048309A1

公开(公告)日：2007-03-01

申请号：US11551347

申请日：2006-10-20

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K38/17 ,  C07K14/715 ,  C07H21/04 ,  C12P21/06 ,  A61K39/395

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

公开(公告)号：US20070048308A1

公开(公告)日：2007-03-01

申请号：US11551334

申请日：2006-10-20

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K39/395 ,  C07H21/04 ,  C12P21/06 ,  C07K14/715

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

公开(公告)号：US20070048307A1

公开(公告)日：2007-03-01

申请号：US11551322

申请日：2006-10-20

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K39/395 ,  C07H21/04 ,  C12P21/06 ,  C07K14/715

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zyctor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zyctor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

摘要翻译： 新的多肽，编码多肽的多核苷酸以及相关组合物和方法公开于zyctor17，一种新的细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zyctor17的多核苷酸位于染色体5上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

公开(公告)号：US20070048303A1

公开(公告)日：2007-03-01

申请号：US11552243

申请日：2006-10-24

申请人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

发明人： Cindy Sprecher ,  Scott Presnell ,  Zeren Gao ,  Theodore Whitmore ,  Joseph Kuijper ,  Mark Maurer

IPC分类号： A61K39/395 ,  C07K16/28

CPC分类号： C07K14/715

摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.