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公开(公告)号:US6121247A
公开(公告)日:2000-09-19
申请号:US826050
申请日:1997-03-28
CPC分类号: A61K38/217 , C07K14/57 , A61K48/00
摘要: Administration of an expression gene construct for IFN-.gamma. to an affected organ is an effective means of reversing antigen-induced inflammation. Suitable allergic diseases for treatment include atopic asthma, rhinitis, and dermatitis.
摘要翻译: 将IFN-γ的表达基因构建体施用于受影响的器官是逆转抗原诱导的炎症的有效手段。 合适的治疗过敏性疾病包括特应性哮喘,鼻炎和皮炎。
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公开(公告)号:US07507706B1
公开(公告)日:2009-03-24
申请号:US09868123
申请日:1999-12-13
申请人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
发明人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
CPC分类号: C07K14/7155 , A61K38/00 , A61K2039/505 , C07K2319/02
摘要: Polynucleotides encoding the IL-13 receptor and fragments thereof are disclosed. IL-13 receptor proteins, methods for their production, inhibitors of binding of IL-13 and its receptor and methods for their identification are also disclosed. Methods of medical treatment using such molecules and antagonists of the IL-13/IL-13R interaction are also provided.
摘要翻译: 公开了编码IL-13受体的多核苷酸及其片段。 还公开了IL-13受体蛋白质,其生产方法,IL-13及其受体的结合抑制剂及其鉴定方法。 还提供了使用这种分子和IL-13 / IL-13R相互作用的拮抗剂的药物治疗方法。
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公开(公告)号:US20100086516A1
公开(公告)日:2010-04-08
申请号:US12408458
申请日:2009-03-20
申请人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
发明人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
IPC分类号: A61K38/20 , A61K39/395 , C12P21/06 , C12N5/00 , G01N33/566 , C07K14/54 , C07K16/24 , C07H21/04
CPC分类号: G01N33/6863 , G01N2333/54
摘要: Polynucleotides encoding the IL-13 receptor and fragments thereof are disclosed. IL-13 receptor proteins, methods for their production, inhibitors of binding of IL-13 and its receptor and methods for their identification are also disclosed. Methods of medical treatment using such molecules and antagonists of the IL-13/IL-13R interaction are also provided.
摘要翻译: 公开了编码IL-13受体的多核苷酸及其片段。 还公开了IL-13受体蛋白质,其生产方法,IL-13及其受体的结合抑制剂及其鉴定方法。 还提供了使用这种分子和IL-13 / IL-13R相互作用的拮抗剂的药物治疗方法。
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公开(公告)号:US07553487B2
公开(公告)日:2009-06-30
申请号:US10989313
申请日:2004-11-15
申请人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
发明人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew J. Whitters , Clive Wood , Marsha Wills-Karp
CPC分类号: G01N33/6863 , G01N2333/54
摘要: The present invention is directed to methods for treating asthma.
摘要翻译: 本发明涉及治疗哮喘的方法。
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公开(公告)号:US20050277126A1
公开(公告)日:2005-12-15
申请号:US10989313
申请日:2004-11-15
申请人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew Whitters , Clive Wood , Marsha Wills-Karp
发明人: Mary Collins , Debra Donaldson , Lori Fitz , Tamlyn Neben , Matthew Whitters , Clive Wood , Marsha Wills-Karp
CPC分类号: G01N33/6863 , G01N2333/54
摘要: The present invention is directed to methods for treating asthma.
摘要翻译: 本发明涉及治疗哮喘的方法。
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