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    Method and configuration for generating a clock pulse in a data processing system having a number of data channels
    2.
    发明授权
    Method and configuration for generating a clock pulse in a data processing system having a number of data channels 失效
    用于在具有多个数据信道的数据处理系统中产生时钟脉冲的方法和配置

    公开(公告)号：US06910144B2

    公开(公告)日：2005-06-21

    申请号：US09998720

    申请日：2001-11-30

    申请人： Martin Ehlert ,  Karl Schroedinger

    发明人： Martin Ehlert ,  Karl Schroedinger

    IPC分类号： G06F1/06 ,  H03L7/07 ,  H04L7/02 ,  H03K5/13

    CPC分类号： H03L7/07 ,  G06F1/06 ,  H04L7/02

    摘要： A method and a configuration for generating a clock pulse in a data processing system having a number of independent, non-synchronous digital data channels, is described. A phase-locked loop (PLL) circuit derives a reference clock pulse, particularly from the data or a co-supplied clock pulse of a data channel serving as a reference channel, the acquired reference clock pulse is supplied to the data channels and a delay-locked loop (DLL) circuit compensates for differences in a clock pulse frequency between the reference clock pulse and the further data channels. As a result, only one reference clock pulse is sufficient in a data processing system having a number of independent, non-synchronous digital data channels, so that the jitter generated in the system is reduced.

    摘要翻译： 描述了在具有多个独立的非同步数字数据通道的数据处理系统中产生时钟脉冲的方法和配置。 锁相环（PLL）电路特别是从作为参考通道的数据通道的数据或共同提供的时钟脉冲中导出参考时钟脉冲，将获取的参考时钟脉冲提供给数据通道，并且延迟 锁定回路（DLL）电路补偿参考时钟脉冲和其他数据通道之间的时钟脉冲频率的差异。 结果，在具有多个独立的非同步数字数据通道的数据处理系统中只有一个参考时钟脉冲是足够的，使得在系统中产生的抖动减小。

    Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material
    5.
    发明授权
    Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material 有权
    紫杉醇含量高的紫杉醇高产量提取方法

    公开(公告)号：US6136989A

    公开(公告)日：2000-10-24

    申请号：US223694

    申请日：1998-12-30

    申请人： Samuel Siang Kiang Foo ,  Yili Bai ,  Martin Ehlert

    发明人： Samuel Siang Kiang Foo ,  Yili Bai ,  Martin Ehlert

    IPC分类号： C12P17/02 ,  A61K31/337 ,  A61K35/74 ,  A61K36/00 ,  A61P35/00 ,  C07D305/14 ,  C12R1/18

    CPC分类号： C07D305/14

    摘要： A method of isolating paclitaxel from pactitaxel-containing material that includes the steps of obtaining an acetone mixture of the paclitaxel-containing material, then mixing the acetone mixture with an aqueous solvent to form an aqueous supernatant and a precipitate, wherein the precipitate contains at least 3-times higher paclitaxel content than the paclitaxel extract. The acetone/water precipitation step provides a high yield of highly pure paclitaxel that is suitable for industrial scale isolation using conventional normal-phase silica chromatography steps, and the preparation of pharmaceutical compositions containing paclitaxel.

    摘要翻译： 一种从含有脉石素的材料中分离紫杉醇的方法，包括以下步骤：获得含紫杉醇的材料的丙酮混合物，然后将丙酮混合物与水性溶剂混合以形成含水上清液和沉淀物，其中沉淀物至少含有 紫杉醇含量高于紫杉醇提取物的3倍。 丙酮/水沉淀步骤提供高产量的高纯度紫杉醇，其适用于使用常规正相硅胶色谱步骤的工业规模分离，以及含有紫杉醇的药物组合物的制备。