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    Pressure reducing folding system that adapts to booklet thickness
    3.
    发明授权
    Pressure reducing folding system that adapts to booklet thickness 有权
    适应小册子厚度的减压折叠系统

    公开(公告)号：US08444540B2

    公开(公告)日：2013-05-21

    申请号：US12824589

    申请日：2010-06-28

    申请人： Ian Parks ,  Richard Hubbard ,  Jeff Ryan ,  Stephen May ,  Martin Lloyd

    发明人： Ian Parks ,  Richard Hubbard ,  Jeff Ryan ,  Stephen May ,  Martin Lloyd

    IPC分类号： B31F1/10

    CPC分类号： B41F13/56 ,  G03G15/6538 ,  G03G2215/00936

    摘要： A device for folding sheets of a medium into a booklet is provided. The device includes a frame; a cam mechanism attached to the frame; a lever attached to the frame, the lever being actuated by the cam mechanism; a first scissor arm attached to the frame, the first scissor arm being actuated by the lever; a pair of first rolls, one of the first rolls being movable by the first scissor arm; a second scissor arm attached to the frame, the second scissor arm being actuated by the lever; a pair of second rolls, one of the second rolls being movable by the second scissor arm; a crease blade for contacting the sheets to create a crease in the sheets; and a controller that controls a position of the crease blade, a gap between the pair of first rolls, and a gap between the pair of second rolls.

    摘要翻译： 提供了一种用于将介质折叠成小册子的设备。 该装置包括一个框架; 附接到框架的凸轮机构; 连接到所述框架的杆，所述杆由所述凸轮机构致动; 附接到框架的第一剪刀臂，第一剪刀臂由杠杆驱动; 一对第一辊，第一辊中的一个可由第一剪刀臂移动; 附接到所述框架的第二剪刀臂，所述第二剪刀臂由所述杠杆致动; 一对第二辊，第二辊中的一个可由第二剪刀臂移动; 用于接触片材以在片材中产生折痕的折痕刀片; 以及控制器，其控制折痕刀片的位置，一对第一辊子之间的间隙和一对第二辊筒之间的间隙。

    PRESSURE REDUCING FOLDING SYSTEM THAT ADAPTS TO BOOKLET THICKNESS
    4.
    发明申请
    PRESSURE REDUCING FOLDING SYSTEM THAT ADAPTS TO BOOKLET THICKNESS 有权
    压力降低折叠系统，适应于书本厚度

    公开(公告)号：US20110316214A1

    公开(公告)日：2011-12-29

    申请号：US12824589

    申请日：2010-06-28

    申请人： Ian PARKS ,  Richard HUBBARD ,  Jeff RYAN ,  Stephen MAY ,  Martin LLOYD

    发明人： Ian PARKS ,  Richard HUBBARD ,  Jeff RYAN ,  Stephen MAY ,  Martin LLOYD

    IPC分类号： B41F13/56 ,  B41L43/08

    CPC分类号： B41F13/56 ,  G03G15/6538 ,  G03G2215/00936

    摘要： A device for folding sheets of a medium into a booklet is provided. The device includes a frame; a cam mechanism attached to the frame; a lever attached to the frame, the lever being actuated by the cam mechanism; a first scissor arm attached to the frame, the first scissor arm being actuated by the lever; a pair of first rolls, one of the first rolls being movable by the first scissor arm; a second scissor arm attached to the frame, the second scissor arm being actuated by the lever; a pair of second rolls, one of the second rolls being movable by the second scissor arm; a crease blade for contacting the sheets to create a crease in the sheets; and a controller that controls a position of the crease blade, a gap between the pair of first rolls, and a gap between the pair of second rolls. The rotation of the cam mechanism through a first period of rotation causes the crease blade to move in a contact direction to create the crease in the sheets by pushing the sheets between the first rolls, the rotation of the cam mechanism through a second period of rotation causes the crease blade to move in a retracting direction away from the sheets, the gap between the pair of first rolls is controlled by the controller based on a total thickness of the sheets to be folded, and the position of the crease blade is controlled by the controller based on the total thickness of the sheets to be folded.

    摘要翻译： 提供了一种用于将介质折叠成小册子的设备。 该装置包括一个框架; 附接到框架的凸轮机构; 连接到所述框架的杆，所述杆由所述凸轮机构致动; 附接到框架的第一剪刀臂，第一剪刀臂由杠杆驱动; 一对第一辊，第一辊中的一个可由第一剪刀臂移动; 附接到所述框架的第二剪刀臂，所述第二剪刀臂由所述杠杆致动; 一对第二辊，第二辊中的一个可由第二剪刀臂移动; 用于接触片材以在片材中产生折痕的折痕刀片; 以及控制器，其控制折痕刀片的位置，一对第一辊子之间的间隙和一对第二辊筒之间的间隙。 凸轮机构通过第一旋转周期的旋转使得折痕刀片在接触方向上移动，以通过在第一辊之间推动片材而产生折痕，凸轮机构通过第二旋转周期的旋转 使得折痕刀片沿着退回方向移动离开片材，一对第一辊子之间的间隙由控制器基于要折叠的片材的总厚度来控制，并且折痕刀片的位置由 控制器基于要折叠的片材的总厚度。

    DENGUE DIAGNOSIS AND TREATMENT
    9.
    发明申请
    DENGUE DIAGNOSIS AND TREATMENT 审中-公开
    登革热诊断与治疗

    公开(公告)号：US20100068147A1

    公开(公告)日：2010-03-18

    申请号：US12444549

    申请日：2007-10-05

    申请人： Martin Lloyd Hibberd ,  Thomas Tolfvenstam ,  Joshua Fink ,  Subhash Vasudevan ,  Feng Gu

    发明人： Martin Lloyd Hibberd ,  Thomas Tolfvenstam ,  Joshua Fink ,  Subhash Vasudevan ,  Feng Gu

    IPC分类号： A61K38/06 ,  C12Q1/70 ,  A61K49/00 ,  C12Q1/37 ,  C12Q1/00 ,  G01N33/569 ,  C07K5/00

    CPC分类号： G01N33/56983 ,  G01N2333/185 ,  G01N2469/10 ,  Y02A50/53

    摘要： We describe a method of providing an indication useful in the diagnosis or prognosis of dengue, the method comprising detecting a change in the expression pattern or level of: (a) a ubiquitin-proteasome pathway protein; (b) a interferon-related protein; or (c) an NF-κB-mediated cytokine/chemokine response protein. We also describe a method of identifying a molecule suitable for the treatment or prevention of dengue, the method comprising determining if a candidate molecule is an agonist or antagonist of any one or more of these proteins.

    摘要翻译： 我们描述一种提供可用于登革热诊断或预后的指征的方法，所述方法包括检测表达模式或水平的变化：（a）泛素 - 蛋白酶体途径蛋白; （b）干扰素相关蛋白; 或（c）NF-κB介导的细胞因子/趋化因子应答蛋白。 我们还描述了鉴定适于治疗或预防登革热的分子的方法，所述方法包括确定候选分子是否是这些蛋白质中的任何一种或多种的激动剂或拮抗剂。

    Micromechanically manufactured infrared transmitter
    10.
    发明申请
    Micromechanically manufactured infrared transmitter 审中-公开
    微机械制造的红外发射器

    公开(公告)号：US20060067656A1

    公开(公告)日：2006-03-30

    申请号：US11234145

    申请日：2005-09-26

    申请人： Gerhard Mueller ,  Olaf Schulz ,  Simon Ahlers ,  Jan Spanhake ,  Martin Lloyd

    发明人： Gerhard Mueller ,  Olaf Schulz ,  Simon Ahlers ,  Jan Spanhake ,  Martin Lloyd

    IPC分类号： H05B1/00

    CPC分类号： H05B3/0052 ,  G01N27/122 ,  H05B1/0244

    摘要： A micromechanical infrared radiator has a radiator surface supported in a carrier chip. The radiator surface can be heated by a heating device. As a function of a temperature measurement, the heating power can be controlled such that the radiator surface assumes a defined temperature. For direct temperature measurement, a micromechanical temperature sensor in the form of a metal resistance is integrated in the radiator surface.

    摘要翻译： 微机械红外辐射器具有支撑在载体芯片中的散热器表面。 散热器表面可以通过加热装置加热。 作为温度测量的函数，可以控制加热功率，使得散热器表面呈现定义的温度。 对于直接的温度测量，在散热器表面集成了金属电阻形式的微机械温度传感器。