-
1.
公开(公告)号:US4526866A
公开(公告)日:1985-07-02
申请号:US482356
申请日:1983-04-05
申请人: Yasuji Kido , Tsutomu Yoshida , Toshinari Hamakado , Masami Anno , Takahiro Harada , Yoshinobu Motoki
发明人: Yasuji Kido , Tsutomu Yoshida , Toshinari Hamakado , Masami Anno , Takahiro Harada , Yoshinobu Motoki
IPC分类号: A61K38/00 , A61K38/55 , A61P9/12 , A61P43/00 , C07K4/06 , C07K14/005 , C07K14/195 , C07K14/41 , C07K14/81 , C12N9/99 , C12P21/00 , C12R1/465 , C12P1/06
CPC分类号: C07K4/04 , C12N9/99 , A61K38/00 , Y10S435/886
摘要: A novel enzyme inhibitor of angiotensin I-converting enzyme was produced from an actinomycetes belonging to genus Streptomyces. This enzyme inhibitor is a peptide, and specifically inhibits the angiotensin I-converting enzyme, but does not inhibit thermolycin, pepsin and .alpha.-chymotrypsin.
摘要翻译: 血管紧张素I转换酶的新型酶抑制剂由属于链霉菌属的放线菌产生。 该酶抑制剂是一种肽,特异性抑制血管紧张素I-转化酶,但不抑制嗜热丝蛋白,胃蛋白酶和α-胰凝乳蛋白酶。