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公开(公告)号：US09579194B2
公开(公告)日：2017-02-28
申请号：US12603315
申请日：2009-10-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0016 , A61F2230/00 , A61F2230/0013 , A61F2230/0054 , A61F2230/0065
摘要： A method and device for reducing paravalvular leakage upon implantation of a replacement heart valve is provided. The valve assembly includes a tissue or bioprosthetic heart valve attached to an anchoring structure. The anchoring structure includes an inlet rim that is substantially C-shaped in cross section to form a concave landing zone. The anchoring structure self-seats when implanted in the sinus of a patient with the proximal and distal ends of the C-shaped inlet rim pushed against the aorta to effectively prevent paravalvular leakage.
摘要翻译： 提供了一种用于在置换心脏瓣膜植入时减少瓣膜漏出的方法和装置。 瓣膜组件包括连接到锚固结构的组织或生物假体心脏瓣膜。 锚定结构包括入口边缘，该入口边缘的横截面基本上为C形，以形成凹入的着陆区域。 当植入患者的窦内时，锚定结构自行座位，其中C形入口边缘的近端和远端被推压到主动脉上，以有效地防止瓣膜溢出。
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公开(公告)号：US09504569B2
公开(公告)日：2016-11-29
申请号：US12870614
申请日：2010-08-27
CPC分类号： A61F2/2436 , A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2002/9517 , A61F2002/9522
摘要： A delivery device for a stented heart valve that includes a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein.
摘要翻译： 一种用于支架式心脏瓣膜的输送装置，其包括手柄，从手柄延伸的内导管轴，并且在远端具有放大的缓冲元件，从手柄延伸并围绕内导管轴可滑动地联接的外导管轴，以及 用于控制外导管轴相对于内导管轴的纵向移动的缩回机构。 外导管轴包括在远端处的大致圆柱形的壳体，其被构造成在其中容纳保险杠元件。
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公开(公告)号：US20110056064A1
公开(公告)日：2011-03-10
申请号：US12870593
申请日：2010-08-27
IPC分类号： A61F2/84
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2002/9522 , B25B27/10 , Y10T29/49925 , Y10T29/53265 , Y10T29/53657
摘要： A crimping tool for crimping a stented heart valve comprises a housing having a front wall and a back wall, a compression assembly disposed between the front wall and the back wall and including a stent receiving chamber therewithin for receiving a stented heart valve, and a delivery device holder slidably coupled to the front wall of the housing. The compression assembly is movable between an uncrimped position and a crimped position to reduce the diameter of the stented heart valve.
摘要翻译： 用于压接支架式心脏瓣膜的压接工具包括具有前壁和后壁的壳体，设置在前壁和后壁之间的压缩组件，并且其中包括用于接收支架式心脏瓣膜的支架接收室，以及输送 装置保持器可滑动地联接到壳体的前壁。 压缩组件可在未夹紧位置和压接位置之间移动，以减小支架式心脏瓣膜的直径。
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公开(公告)号：US07326564B2
公开(公告)日：2008-02-05
申请号：US09789130
申请日：2001-02-20
申请人： Beverley I. Lundell , Robert L. Meisch , John R. Wilson , Matthew W. Weston , M. William Mirsch, II , Kathy J. Grossinger, legal representative
IPC分类号： C12M3/00
CPC分类号： A61F2/2472 , A61F2/022 , A61F2/2475 , Y10S623/912 , Y10S623/915
摘要： In some embodiments, a flow system includes a medical device mount, fluid and a conduit containing the fluid and medical device mount. The conduit is mounted on an assembly that moves the conduit along with the medical device mount to induce relative motion of the fluid relative to the medical device mount. In preferred embodiments, pulsatile fluid motion is generated. In some embodiments, the fluid includes viable cells. In alternative embodiments, a flow system includes a continuous flow pump connected to a conduit loop having multiple branch conduits downstream from the pump providing alternative paths over a section of the conduit loop. Each branch conduit has a valve controlling flow through the branch. In some embodiments, at least one branch includes a medical device mount.
摘要翻译： 在一些实施例中，流动系统包括医疗装置支架，流体和容纳流体和医疗装置支架的导管。 导管安装在组件上，该组件与医疗装置安装座一起移动管道以引起流体相对于医疗装置安装座的相对运动。 在优选实施例中，产生脉动流体运动。 在一些实施例中，流体包括活细胞。 在替代实施例中，流动系统包括连接到导管回路的连续流动泵，其具有在泵下游的多个分支管道，在管道环路的一部分上提供替代路径。 每个分支导管都有一个控制流经分支的阀门。 在一些实施例中，至少一个分支包括医疗装置支架。
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公开(公告)号：US09555528B2
公开(公告)日：2017-01-31
申请号：US12870584
申请日：2010-08-27
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2439 , A61F2002/9517 , A61F2002/9522 , B25B27/10
摘要： A delivery device for a stented heart valve includes a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.
摘要翻译： 用于支架式心脏瓣膜的递送装置包括手柄，从手柄的远端延伸的细长轴和具有联接到细长轴的近端和开口远端的圆锥形壳体，所述锥形壳体具有锥形腔 其中具有与锥形壳体的近端相邻的第一内径和与锥形壳体的敞开的远端相邻的较大的第二内径。
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公开(公告)号：US08479380B2
公开(公告)日：2013-07-09
申请号：US12870593
申请日：2010-08-27
IPC分类号： B23P19/00
CPC分类号： A61F2/2427 , A61F2/2412 , A61F2002/9522 , B25B27/10 , Y10T29/49925 , Y10T29/53265 , Y10T29/53657
摘要： A crimping tool for crimping a stented heart valve comprises a housing having a front wall and a back wall, a compression assembly disposed between the front wall and the back wall and including a stent receiving chamber therewithin for receiving a stented heart valve, and a delivery device holder slidably coupled to the front wall of the housing. The compression assembly is movable between an uncrimped position and a crimped position to reduce the diameter of the stented heart valve.
摘要翻译： 用于压接支架式心脏瓣膜的压接工具包括具有前壁和后壁的壳体，设置在前壁和后壁之间的压缩组件，并且其中包括用于接收支架式心脏瓣膜的支架接收室，以及输送 装置保持器可滑动地联接到壳体的前壁。 压缩组件可在未夹紧位置和压接位置之间移动，以减小支架式心脏瓣膜的直径。
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公开(公告)号：US20110106246A1
公开(公告)日：2011-05-05
申请号：US12870614
申请日：2010-08-27
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2412 , A61F2/2418 , A61F2/2439 , A61F2002/9517 , A61F2002/9522
摘要： A delivery device for a stented heart valve comprises a handle, an inner catheter shaft extending from the handle and having an enlarged bumper element at a distal end, an outer catheter shaft extending from the handle and slidably coupled around the inner catheter shaft, and a retraction mechanism for controlling longitudinal movement of the outer catheter shaft relative to the inner catheter shaft. The outer catheter shaft includes a generally cylindrical housing at a distal end that is structured to receive the bumper element therein.
摘要翻译： 用于支架式心脏瓣膜的输送装置包括手柄，从手柄延伸的内导管轴，并且在远端具有放大的保险杠元件，从手柄延伸并围绕内导管轴可滑动地联接的外导管轴，以及 用于控制外导管轴相对于内导管轴的纵向移动的缩回机构。 外导管轴包括在远端处的大致圆柱形的壳体，其被构造成在其中容纳保险杠元件。
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公开(公告)号：US20110060404A1
公开(公告)日：2011-03-10
申请号：US12870584
申请日：2010-08-27
IPC分类号： A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2439 , A61F2002/9517 , A61F2002/9522 , B25B27/10
摘要： A delivery device for a stented heart valve comprises a handle, an elongate shaft extending from a distal end of the handle, and a conical housing having a proximal end coupled to the elongate shaft and an open distal end, the conical housing having a conical lumen therein with a first internal diameter adjacent to the proximal end of the conical housing and a larger second internal diameter adjacent to the open distal end of the conical housing.
摘要翻译： 用于支架式心脏瓣膜的递送装置包括手柄，从手柄的远端延伸的细长轴和具有联接到细长轴的近端和敞开的远端的圆锥形壳体，锥形壳体具有圆锥形内腔 其中具有与锥形壳体的近端相邻的第一内径和与锥形壳体的敞开的远端相邻的较大的第二内径。
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公开(公告)号：US20100100176A1
公开(公告)日：2010-04-22
申请号：US12603315
申请日：2009-10-21
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2220/0016 , A61F2230/00 , A61F2230/0013 , A61F2230/0054 , A61F2230/0065
摘要： A method and device for reducing paravalvular leakage upon implantation of a replacement heart valve is provided. The valve assembly includes a tissue or bioprosthetic heart valve attached to an anchoring structure. The anchoring structure includes an inlet rim that is substantially C-shaped in cross section to form a concave landing zone. The anchoring structure self-seats when implanted in the sinus of a patient with the proximal and distal ends of the C-shaped inlet rim pushed against the aorta to effectively prevent paravalvular leakage.
摘要翻译： 提供了一种用于在置换心脏瓣膜植入时减少瓣膜漏出的方法和装置。 瓣膜组件包括连接到锚固结构的组织或生物假体心脏瓣膜。 锚定结构包括入口边缘，该入口边缘的横截面基本上为C形，以形成凹入的着陆区域。 当植入患者的窦内时，锚定结构自行座位，其中C形入口边缘的近端和远端被推压到主动脉上，以有效地防止瓣膜溢出。
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公开(公告)号：US07252681B2
公开(公告)日：2007-08-07
申请号：US10368085
申请日：2003-02-13
申请人： Todd A Berg , Alex A Peterson , Matthew W Weston
发明人： Todd A Berg , Alex A Peterson , Matthew W Weston
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0075
摘要： A replacement heart valve structure including a structure of tissue which is an intact, mammalian heart valve that has been harvested and treated to preserve it. A conventional fabric sleeve is typically disposed concentrically around the outside of the tissue structure. A support structure is included to facilitate implanting the heart valve by somewhat increasing the stability of the heart valve structure, but without unduly rigidifying it. An annular sewing cuff may be added adjacent the blood inflow end of the valve structure to facilitate making the annular suture line that is required at that end.
摘要翻译： 替代心脏瓣膜结构，其包括组织的结构，其是已经被收获并被处理以保存的完整的哺乳动物心脏瓣膜。 传统的织物套筒通常围绕组织结构的外部同心地设置。 包括支撑结构以便于通过稍微增加心脏瓣膜结构的稳定性而不会使其过度硬化来植入心脏瓣膜。 可以在阀结构的血液流入端附近添加环形缝合箍，以便于制造在该端所需的环形缝合线。
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