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公开(公告)号:US20130251726A1
公开(公告)日:2013-09-26
申请号:US13792098
申请日:2013-03-10
申请人: John Mascola , Dennis R. Burton , Wayne Koff , Peter Kwong , Gary Nabel , Sanjay K. Phogat , Pascal Raymond Georges Poignard , Melissa Danielle De Jean St. Marcel Simek-Lemos , Xueling Wu , Tongqing Zhou , Zhi-Yong Yang
发明人: John Mascola , Dennis R. Burton , Wayne Koff , Peter Kwong , Gary Nabel , Sanjay K. Phogat , Pascal Raymond Georges Poignard , Melissa Danielle De Jean St. Marcel Simek-Lemos , Xueling Wu , Tongqing Zhou , Zhi-Yong Yang
CPC分类号: C07K16/1063 , A61K39/42 , A61K45/06 , A61K2039/505 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/76 , C07K2317/92 , G01N33/56988
摘要: The present application relates novel HIV-1 broadly neutralizing antibodies. The antibodies of the present invention are further characterized by their ability to bind epitopes from the Env proteins. The invention also provides light and heavy chain variable region sequences. Compositions for prophylaxis, diagnosis and treatment of HIV infection are provided.
摘要翻译: 本申请涉及新型HIV-1广泛中和抗体。 本发明的抗体的特征还在于它们能够结合来自Env蛋白的表位。 本发明还提供轻链和重链可变区序列。 提供了预防,诊断和治疗艾滋病毒感染的组合。