公开(公告)号：US10407388B2

公开(公告)日：2019-09-10

申请号：US15759588

申请日：2012-05-23

申请人： Mi Ock Lee ,  Hyeung Geun Park ,  Eun Jin Kim ,  Ho Young Son ,  Hyo Jun Jung ,  Suck Chang Hong ,  Tae Young Na

发明人： Mi Ock Lee ,  Hyeung Geun Park ,  Eun Jin Kim ,  Ho Young Son ,  Hyo Jun Jung ,  Suck Chang Hong ,  Tae Young Na

IPC分类号： C07C335/12 ,  A61P9/10 ,  A61P1/16 ,  A61P3/06 ,  A61P29/00

摘要： Provided is a compound activating RORα gene, particularly a JC1 compound containing CGP52608 thiazolidinedione as a lead substance, and a pharmaceutically acceptable salt thereof. The compound is a lipid accumulation inhibitor and applicable to the treatment of metabolic diseases or inflammatory diseases.

公开(公告)号：US20180265462A1

公开(公告)日：2018-09-20

申请号：US15759588

申请日：2012-05-23

申请人： Mi Ock LEE ,  Hyeung Geun PARK ,  Eun Jin KIM ,  Ho Young SON ,  Hyo Jun JUNG ,  Suck Chang HONG ,  Tae Young NA

发明人： Mi Ock LEE ,  Hyeung Geun PARK ,  Eun Jin KIM ,  Ho Young SON ,  Hyo Jun JUNG ,  Suck Chang HONG ,  Tae Young NA

IPC分类号： C07C335/12 ,  A61P29/00 ,  A61P3/06 ,  A61P1/16 ,  A61P9/10

CPC分类号： C07C335/12 ,  A61P1/16 ,  A61P3/06 ,  A61P9/10 ,  A61P29/00

摘要： Provided is a compound activating RORα gene, particularly a JC1 compound containing CGP52608 thiazolidinedione as a lead substance, and a pharmaceutically acceptable salt thereof. The compound is a lipid accumulation inhibitor and applicable to the treatment of metabolic diseases or inflammatory diseases.