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公开(公告)号:US20100239611A1
公开(公告)日:2010-09-23
申请号:US12587955
申请日:2009-10-15
申请人: Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliot
发明人: Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliot
IPC分类号: A61K39/155 , A61K39/39 , C07K7/08 , A61K39/35 , A61K39/10 , A61P31/12 , A61P31/04 , A61P31/10 , A61P33/00
CPC分类号: A61K39/39 , A61K39/099 , A61K39/12 , A61K39/155 , A61K45/06 , A61K47/30 , A61K2039/55516 , A61K2039/55561 , A61K2039/6093 , C07K7/08 , C12N2760/18534
摘要: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
摘要翻译: 描述了增强对所选抗原的免疫应答的方法和组合物。 该方法可用于治疗和预防微生物感染,例如由细菌,病毒,真菌和寄生虫引起的感染。 方法和组合物包括宿主防御肽,聚磷腈和免疫刺激序列,以增强对共同施用的抗原的免疫应答。
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公开(公告)号:US09061001B2
公开(公告)日:2015-06-23
申请号:US12587955
申请日:2009-10-15
申请人: Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliott
发明人: Sylvia van Drunen Littel-van den Hurk , Volker Gerdts , Andrew Potter , Lorne Babiuk , Robert Hancock , Scott Halperin , Jennifer Kovacs-Nolan , George Mutwiri , Song Lee , Mi-Na Kweon , Jason Kindrachuk , Melissa Elliott
IPC分类号: A61K49/00 , A61K47/00 , A61K38/04 , A61K39/39 , A61K39/02 , A61K39/155 , C07K7/08 , A61K45/06 , A61K47/30 , A61K39/00
CPC分类号: A61K39/39 , A61K39/099 , A61K39/12 , A61K39/155 , A61K45/06 , A61K47/30 , A61K2039/55516 , A61K2039/55561 , A61K2039/6093 , C07K7/08 , C12N2760/18534
摘要: Methods and compositions for enhancing an immune response to a selected antigen are described. The methods are useful for the treatment and prevention of microbial infections, such as infections caused by bacteria, viruses, fungi and parasites. The methods and compositions include host defense peptides, polyphosphazenes and immunostimulatory sequences to enhance the immune response to a coadministered antigen.
摘要翻译: 描述了增强对所选抗原的免疫应答的方法和组合物。 该方法可用于治疗和预防微生物感染,例如由细菌,病毒,真菌和寄生虫引起的感染。 方法和组合物包括宿主防御肽,聚磷腈和免疫刺激序列,以增强对共同施用的抗原的免疫应答。
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