公开(公告)号：US08676512B2

公开(公告)日：2014-03-18

申请号：US12809791

申请日：2008-12-17

申请人： Klaus Balschat ,  Alfred Gagel ,  Michael Kulz ,  Reiner Spickermann

发明人： Klaus Balschat ,  Alfred Gagel ,  Michael Kulz ,  Reiner Spickermann

IPC分类号： A61M1/34 ,  G06F19/00 ,  G06F17/40

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M1/34 ,  A61M1/3403 ,  A61M1/341 ,  A61M1/3413 ,  A61M1/36 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/50

摘要： A method and device are provided for determining the transmembrane pressure during an extracorporeal blood treatment in which blood flows at a defined blood flow rate through an arterial blood conduit of an extracorporeal blood circuit into the inlet of a first chamber of a dialyzer, which is divided by a semipermeable membrane into the first chamber and a second chamber, and flows through a venous blood conduit from the outlet of the first chamber of the dialyzer, while dialysis liquid flows through a dialysis liquid supply conduit into the inlet of the second chamber of the dialyzer and flows through a dialaysis liquid discharge conduit from the outlet of the second chamber of the dialyzer. The method and the device for determining the transmembrane pressure are such that the pressure on the blood side and on the dialysis liquid side of the dialyzer is measured with relatively little technical outlay, specifically with fewer than four pressure sensors, and a preliminary uncorrected value is calculated for the transmembrane pressure and is thereafter corrected by a correction variable that is dependent on a variable correlating with the viscosity of the blood.

摘要翻译： 提供了一种用于在体外血液处理期间确定跨膜压力的方法和装置，其中血液以限定的血液流量通过体外血液回路的动脉血管流入到透析器的第一腔室的入口中，该第一腔室被分开 通过半透膜进入第一腔室和第二腔室，并且从透析器的第一腔室的出口流过静脉血液导管，同时透析液体流过透析液体供应管道进入第二腔室的入口 透析器，并从透析器的第二腔室的出口流过拨号液体排出导管。 用于确定跨膜压力的方法和装置使得透析器的血液侧和透析液体侧的压力以相对较少的技术支出来测量，特别是使用少于四个的压力传感器，初步未校正的值是 计算跨膜压力，然后通过依赖于与血液粘度相关的变量的校正变量进行校正。