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公开(公告)号:US5980946A
公开(公告)日:1999-11-09
申请号:US922749
申请日:1997-09-03
申请人: Richard E. Jones , Mike T. Li
发明人: Richard E. Jones , Mike T. Li
IPC分类号: A61K9/107 , A61K9/00 , A61K31/135 , A61K31/505 , A61K45/00 , A61K47/42 , A61P9/00 , A61P35/00 , A61K9/10
CPC分类号: A61K9/0024 , A61K47/42
摘要: Disclosed are proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45.degree. C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.
摘要翻译: 公开了包含胶原蛋白和有效量的相容的细胞毒性药物的蛋白质组合物,其组合物的特征在于具有小于约45℃的单一胶原转变温度。这些组合物具有增强的注射部位的细胞毒性药物的保留性,并且是 光学半透明。
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公开(公告)号:US5750146A
公开(公告)日:1998-05-12
申请号:US431084
申请日:1995-04-28
申请人: Richard E. Jones , Mike T. Li
发明人: Richard E. Jones , Mike T. Li
IPC分类号: A61K9/107 , A61K9/00 , A61K31/135 , A61K31/505 , A61K45/00 , A61K47/42 , A61P9/00 , A61P35/00 , A61K9/10
CPC分类号: A61K9/0024 , A61K47/42
摘要: Disclosed are translucent proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45.degree. C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.
摘要翻译: 公开了包含胶原和有效量的相容的细胞毒性药物的半透明蛋白质组合物,该组合物的特征在于具有小于约45℃的单一胶原转变温度。这些组合物具有增强的注射部位的细胞毒性药物的保留性, 是光学半透明的。
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