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公开(公告)号:US5980946A
公开(公告)日:1999-11-09
申请号:US922749
申请日:1997-09-03
申请人: Richard E. Jones , Mike T. Li
发明人: Richard E. Jones , Mike T. Li
IPC分类号: A61K9/107 , A61K9/00 , A61K31/135 , A61K31/505 , A61K45/00 , A61K47/42 , A61P9/00 , A61P35/00 , A61K9/10
CPC分类号: A61K9/0024 , A61K47/42
摘要: Disclosed are proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45.degree. C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.
摘要翻译: 公开了包含胶原蛋白和有效量的相容的细胞毒性药物的蛋白质组合物,其组合物的特征在于具有小于约45℃的单一胶原转变温度。这些组合物具有增强的注射部位的细胞毒性药物的保留性,并且是 光学半透明。
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公开(公告)号:US5750146A
公开(公告)日:1998-05-12
申请号:US431084
申请日:1995-04-28
申请人: Richard E. Jones , Mike T. Li
发明人: Richard E. Jones , Mike T. Li
IPC分类号: A61K9/107 , A61K9/00 , A61K31/135 , A61K31/505 , A61K45/00 , A61K47/42 , A61P9/00 , A61P35/00 , A61K9/10
CPC分类号: A61K9/0024 , A61K47/42
摘要: Disclosed are translucent proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition temperature of less than about 45.degree. C. Such compositions possess enhanced retention of the cytotoxic drug at the site of injection and are optically translucent.
摘要翻译: 公开了包含胶原和有效量的相容的细胞毒性药物的半透明蛋白质组合物,该组合物的特征在于具有小于约45℃的单一胶原转变温度。这些组合物具有增强的注射部位的细胞毒性药物的保留性, 是光学半透明的。
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公开(公告)号:US5851403A
公开(公告)日:1998-12-22
申请号:US869045
申请日:1997-06-04
CPC分类号: B01J20/2803 , B01D15/00 , B01D53/02 , B01J20/20 , B01J20/28009 , B01J20/28023 , B01J20/28028 , B01J20/28045 , Y10T428/24149 , Y10T442/2975
摘要: Conductive and/or chemically absorptive ceramic fibers are woven with optional non-conductive/non-absorptive ceramic fibers to create a fiber reinforcement which is impregnated with a ceramic-material-producing (pre-ceramic polymer) binder and heated to create the ceramic honeycomb with controlled ohmic loss and/or chemical absorption properties. The desired properties of the honeycomb material can be provided by the conductive and/absorptive ceramic fibers alone or in combination with non-fibrous or fibrous conductive and/or absorptive ceramic material provided by the binder, typically a preceramic polymer which may or may not contain dispersed ceramic materials; after the honeycomb is formed, the non-fibrous or fibrous conductive and/or absorptive ceramic material is interspersed throughout the honeycomb. By heating the impregnated fiber reinforcement in the absence of oxygen, carbon from any carbon-containing materials within the binder remain as a part of the honeycomb material. The honeycomb can be loaded with additional carbon or carbon-containing fibers by repeating the loading and heating in the absence of oxygen steps. For applications requiring long-term thermo-oxidative resistance, refractory ceramics like pure silicon carbide can be substituted for the fibers or fillers employed.
摘要翻译: 导电和/或化学吸收陶瓷纤维用可选的非导电/非吸收性陶瓷纤维编织,以产生纤维增强物,其被陶瓷材料生产(预陶瓷聚合物)粘合剂浸渍并加热以产生陶瓷蜂窝体 具有受控的欧姆损失和/或化学吸收性能。 蜂窝材料的所需性能可以由导电和/或吸收性陶瓷纤维单独提供,或与由粘合剂提供的非纤维或纤维状导电和/或吸收性陶瓷材料组合提供,通常为可以含或不含有 分散陶瓷材料; 在形成蜂窝体之后,非纤维状或纤维状的导电和/或吸收性陶瓷材料穿过整个蜂窝体。 通过在不存在氧的情况下加热浸渍的纤维增强材料,粘合剂中任何含碳材料的碳残留作为蜂窝材料的一部分。 通过在不存在氧气步骤的情况下重复加载和加热,蜂窝体可以加载额外的碳或含碳纤维。 对于需要长期耐热氧化性的应用,像纯碳化硅这样的耐火陶瓷可以代替所用的纤维或填料。
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公开(公告)号:US5726421A
公开(公告)日:1998-03-10
申请号:US483363
申请日:1995-06-07
申请人: Grier S. Fleischhauer , Patrick H. Hayes , Charles T. Higgins , Richard E. Jones , Robert L. Ripley , T. Paul Beane , J. Robert Nelson, Jr.
发明人: Grier S. Fleischhauer , Patrick H. Hayes , Charles T. Higgins , Richard E. Jones , Robert L. Ripley , T. Paul Beane , J. Robert Nelson, Jr.
CPC分类号: A24F47/008
摘要: An ejection system is provided which has a mechanism such as a plunger which is positioned to eject at least a portion of a cigarette from the lighter cavity upon actuation by a smoker. The plunger is also positionable to occlude the lighter opening to protect the lighter cavity from dust, moisture, etc. The plunger is shaped, located and arranged to apply a force on the cigarette end inserted into the lighter. Further, an icon based indicator informs the smoker of the status of a cigarette inserted into the lighter.
摘要翻译: 提供了一种排出系统,其具有诸如柱塞的机构,其被定位成在吸烟者致动时从香烟喷射至少一部分香烟。 柱塞还可以定位成闭塞较轻的开口,以保护较轻的空腔免受灰尘,潮湿等。柱塞的形状,位置和布置成对插入打火机的香烟端上施加力。 此外,基于图标的指示器向吸烟者通知插入打火机中的香烟的状态。
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公开(公告)号:US5279294A
公开(公告)日:1994-01-18
申请号:US499085
申请日:1990-03-26
申请人: Paul J. Anderson , Ross A. Jessen , David R. Linde , Richard E. Jones , Bert Walter , Paul E. Christenson
发明人: Paul J. Anderson , Ross A. Jessen , David R. Linde , Richard E. Jones , Bert Walter , Paul E. Christenson
CPC分类号: C12Q1/54 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150358 , A61B5/150435 , A61B5/150664 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157 , G01N33/52 , A61B2560/0252 , A61B2562/0295
摘要: Hand-held shirt-pocket portable instrument for quantitative measurement of glucose or analysis in biological fluids. The system accepts a disposable diagnostic reagent test device which has a reagent carrier and mode of identifying to the instrument the reagent lot characteristics. The instrument includes a housing structure having a visual LCD readout, a microprocessor, and photosensing circuitry which measures the change of color of the reagent carrier upon reaction in the reacting chemistry of the disposable test device. The housing also includes a spring arrangement for actuating a disposable lancet into the skin for generating blood. The disposable diagnostic reagent unit includes a configuration for transporting of the blood in the regent unit. The system includes verification and calibration sequences for the electronics, the chemistry of an unused disposable unit, the presence of a blood sample, and the ambient temperature. The system also provides for storing a plurality of analysis readings.
摘要翻译: 用于定量测量葡萄糖或生物液体分析的手提式袖珍便携式仪器。 该系统接受一次性诊断试剂测试装置,其具有试剂载体和向仪器鉴定试剂批次特性的模式。 仪器包括具有视觉LCD读数的壳体结构,微处理器和光敏电路,其测量在一次性测试装置的反应化学中反应时试剂载体的颜色变化。 壳体还包括用于致动一次性刺血针进入皮肤以产生血液的弹簧装置。 一次性诊断试剂单元包括用于运送摄取单元中的血液的构造。 该系统包括用于电子设备的验证和校准序列,未使用的一次性单元的化学性质,血液样品的存在以及环境温度。 该系统还提供存储多个分析读数。
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公开(公告)号:US4933168A
公开(公告)日:1990-06-12
申请号:US301922
申请日:1981-09-14
CPC分类号: A61K9/008 , A61K31/58 , A61K9/0043 , C07J71/0031
摘要: A unique crystalline polymorphic form of flunisolide is disclosed which is stable in aerosols such as Freon.RTM. mixtures and is valuable in the treatment of respiratory diseases, particularly bronchial asthma and allergic rhinitis.
摘要翻译: 公开了独特的氟尼缩松结晶多晶型物,其在气溶胶如氟利昂TM混合物中是稳定的,并且在治疗呼吸系统疾病,特别是支气管哮喘和过敏性鼻炎中是有价值的。
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公开(公告)号:US4273710A
公开(公告)日:1981-06-16
申请号:US150400
申请日:1980-05-16
IPC分类号: C07J71/00
CPC分类号: C07J71/0031
摘要: A unique crystalline form of flunisolide is prepared by crystallizing flunisolide from a solution of an alkanol of three or four carbon atoms, e.g. n-butanol, containing 0.2 to 5%, preferably 1.0 to 4.0% by volume water.
摘要翻译: 通过从三个或四个碳原子的链烷醇的溶液中结晶氟尼缩松来制备氟尼柳内酯的独特结晶形式,例如, 正丁醇,含有0.2至5%,优选1.0至4.0体积%的水。
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公开(公告)号:USD249467S
公开(公告)日:1978-09-19
申请号:US734266
申请日:1976-10-20
申请人: Richard E. Jones , Joseph R. Quiroz
设计人: Richard E. Jones , Joseph R. Quiroz
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公开(公告)号:US06630168B1
公开(公告)日:2003-10-07
申请号:US08803128
申请日:1997-02-20
IPC分类号: A61K910
CPC分类号: A61K9/0019 , A61K47/10 , A61K47/18 , A61K47/32 , A61K47/38
摘要: Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a substantially non-aqueous gel delivery vehicle comprising at least one polar organic solvent in combination with one or more thickening agents. The subject methods and compositions provide for the enhanced efficacy of regionally or locally administered antiproliferative proliferative agents.
摘要翻译: 提供了用于治疗患有细胞增殖性疾病的宿主的方法和组合物。 在本发明方法中,抗增殖剂在基本上非水性凝胶输送载体中施用,其包含至少一种极性有机溶剂与一种或多种增稠剂的组合。 本发明的方法和组合物提供了区域或局部施用的抗增殖性增殖剂的增强功效。
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公开(公告)号:US06544962B1
公开(公告)日:2003-04-08
申请号:US09714776
申请日:2000-11-15
申请人: Richard E. Jones , Ning Y. Yu
发明人: Richard E. Jones , Ning Y. Yu
IPC分类号: A61K3170
CPC分类号: A61K31/70
摘要: Methods of treating cancer by administration of FMdC followed by administration of a platinate are disclosed.
摘要翻译: 公开了通过施用FMdC治疗癌症的方法,然后施用铂酸盐。
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