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1.发明授权Multiple sclerosis-associated retroviral (MSRV) nucleic acids corresponding to the Env region 失效对应于Env区域的多发性硬化相关逆转录病毒（MSRV）核酸公开(公告)号：US07771927B1
公开(公告)日：2010-08-10
申请号：US09319156
申请日：1998-07-07
申请人： Glaucia Paranhos-Baccala , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
发明人： Glaucia Paranhos-Baccala , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
CPC分类号： C07K14/4713 , C07K14/005 , C12N2740/10022
摘要： The invention concerns a nucleic material, in isolated or purified state, and a nucleotide fragment comprising a nucleotide sequence selected from the group consisting in (i) the sequences SEQ ID NO: 112, SEQ ID NO:114, SEQ ID NO: 117, SEQ ID NO: 120, SEQ ID NO. 124, SEQ ID NO: 130, SEQ ID NO: 141 and SEQ ID NO: 142, (ii) the complementary sequences of sequences (i); and (iii) the sequences equivalent to sequences (ii) and (iii), in particular the sequence having for every series of 100 contiguous monomers, at least 50%, preferably 70% homology with sequences (i) and (ii) respectively. The invention also concerns their uses for detecting a retrovirus associated with multiple sclerosis and/or rheumatoid arthritis.
摘要翻译： 本发明涉及分离或纯化状态的核酸，以及包含选自（i）序列SEQ ID NO：112，SEQ ID NO：114，SEQ ID NO：117， SEQ ID NO：120，SEQ ID NO： 124，SEQ ID NO：130，SEQ ID NO：141和SEQ ID NO：142，（ii）序列（i）的互补序列; 和（iii）与序列（ii）和（iii）相当的序列，特别是具有每100个连续单体的序列的序列，分别与序列（i）和（ii）具有至少50％，优选70％的同源性。 本发明还涉及其用于检测与多发性硬化和/或类风湿性关节炎相关的逆转录病毒的用途。
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2.发明授权Isolated multiple sclerosis (MS)-associated retrovirus (MSRV) nucleic acids corresponding to the gag region 有权分离的多发性硬化（MS）相关逆转录病毒（MSRV）核酸对应于gag区域公开(公告)号：US08088910B2
公开(公告)日：2012-01-03
申请号：US12776893
申请日：2010-05-10
申请人： Glaucia Paranhos-Baccala , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
发明人： Glaucia Paranhos-Baccala , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
CPC分类号： C07K14/4713 , C07K14/005 , C12N2740/10022
摘要： An isolated polynucleotide having a nucleotide sequence selected from the group consisting of (a) SEQ ID NO: 21, (b) the full-length sequences encoding a polypeptide having a peptide sequence selected from the group consisting of SEQ ID NOs: 25 and 26, and (c) the full-length complementary sequences to the sequences set forth in (a) or (b).
摘要翻译： 一种分离的多核苷酸，其具有选自（a）SEQ ID NO：21，（b）编码具有选自SEQ ID NO：25和26的肽序列的多肽的全长序列的核苷酸序列 ，和（c）与（a）或（b）中列出的序列的全长互补序列。
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3.发明申请RETROVIRAL NUCLEIC MATERIAL AND NUCLEOTIDE FRAGMENTS, IN PARTICULAR ASSOCIATED WITH MULTIPLE SCLEROSIS AND/OR RHEUMATOID ARTHRITIS, FOR DIAGNOSTIC, PROPHYLACTIC AND THERAPEUTIC USES 有权特别是与多发性硬化症和/或RHEUMATOID ARTHRITIS相关的替代性核材料和核素片段，用于诊断，预防和治疗用途公开(公告)号：US20100285448A1
公开(公告)日：2010-11-11
申请号：US12776893
申请日：2010-05-10
申请人： Glaucia PARANHOS-BACCALA , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
发明人： Glaucia PARANHOS-BACCALA , Florence Komurian-Pradel , Frederic Bedin , Mireille Sodoyer , Catherine Ott , Francois Mallet , Herve Perron , Bernard Mandrand
CPC分类号： C07K14/4713 , C07K14/005 , C12N2740/10022
摘要： An isolated polynucleotide having a nucleotide sequence selected from the group consisting of (a) SEQ ID NO: 21, (b) the full-length sequences encoding a polypeptide having a peptide sequence selected from the group consisting of SEQ ID NOs: 25 and 26, and (c) the full-length complementary sequences to the sequences set forth in (a) or (b).
摘要翻译： 一种分离的多核苷酸，其具有选自（a）SEQ ID NO：21，（b）编码具有选自SEQ ID NO：25和26的肽序列的多肽的全长序列的核苷酸序列 ，和（c）与（a）或（b）中列出的序列的全长互补序列。
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