公开(公告)号：US08114902B2

公开(公告)日：2012-02-14

申请号：US12226745

申请日：2007-04-27

申请人： Masatoshi Kiuchi ,  Mitsuharu Nakamura ,  Maiko Hamada ,  Kunio Sugahara

发明人： Masatoshi Kiuchi ,  Mitsuharu Nakamura ,  Maiko Hamada ,  Kunio Sugahara

IPC分类号： A61K31/335 ,  C07D319/06

CPC分类号： C07F9/653 ,  C07C217/64 ,  C07C225/16 ,  C07C309/65 ,  C07C323/32 ,  C07C323/38 ,  C07C323/41 ,  C07D333/22 ,  C07D333/34 ,  C07F9/091

摘要： Disclosed is a 2-aminobutanol compound represented by the following formula (I) or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof, as well as a production method of the 2-aminobutanol compound of formula (I). The 2-aminobutanol compounds of formula (I) have few side effects including bradycardia and have superior peripheral blood lymphocyte-decreasing effects.

摘要翻译： 公开了由下式（I）表示的2-氨基丁醇化合物或其药学上可接受的酸加成盐或其水合物或其溶剂合物，以及式（I）的2-氨基丁醇化合物的制备方法 ）。 式（I）的2-氨基丁醇化合物具有很少的副作用，包括心动过缓，并且具有优异的外周血淋巴细胞减少作用。

公开(公告)号：US06343953B2

公开(公告)日：2002-02-05

申请号：US09811570

申请日：2001-03-20

申请人： Mitsuharu Nakamura ,  Takao Murakami

发明人： Mitsuharu Nakamura ,  Takao Murakami

IPC分类号： H01K1340

CPC分类号： H01R13/506 ,  H01R13/512 ,  H01R13/5202

摘要： In a structure for assembling a housing and a connector in which a connector is inserted into a housing, and a fitting surface of the connector adapted to be connected to a mating connector and oriented in a direction perpendicular to an inserting direction projects outside the housing through an opening formed in the housing, an inclined wall which is inclined with respect to the inserting direction of the connector is provided on an inner surface of the housing, an annular inclined flange which opposes to the inclined wall is provided on an outer peripheral side of the fitting surface of the connector, a seal member is interposed between the inclined wall and the inclined flange, the seal member is pressed between the inclined wall and the inclined flange by fixing a substrate provided with the connector to the housing.

摘要翻译： 在用于组装壳体和连接器的结构中，其中连接器插入到壳体中，并且连接器的装配表面适于连接到配合连接器并且在垂直于插入方向的方向上定向突出到壳体外部 形成在壳体中的开口设置在壳体的内表面上相对于连接器的插入方向倾斜的倾斜壁，在该外壳的内表面上设置有与倾斜壁相对的环形倾斜凸缘， 连接器的嵌合表面，密封构件插入在倾斜壁和倾斜凸缘之间，通过将设置有连接器的基板固定到壳体上，将密封构件压在倾斜壁和倾斜凸缘之间。

公开(公告)号：US20120037030A1

公开(公告)日：2012-02-16

申请号：US13145901

申请日：2010-01-21

申请人： Yoji Tasaki ,  Mitsuharu Nakamura ,  Ryutaro Shiraishi ,  Koji Saiki ,  Jianlin Chen

发明人： Yoji Tasaki ,  Mitsuharu Nakamura ,  Ryutaro Shiraishi ,  Koji Saiki ,  Jianlin Chen

IPC分类号： C06D5/00 ,  B60R21/16 ,  B01J7/00

CPC分类号： B60R21/2644 ,  B60R2021/2633 ,  B60R2021/2648 ,  F42B3/04

摘要： A small, lightweight, and inexpensive gas generator for an airbag device. The gas generator for an airbag device according to the present invention includes: a deployment activating initiator that accommodates a predetermined amount of ignition powder and is activated by an impact on a vehicle; a main gas generating agent that generates a main gas for inflating an airbag when burned; a main gas generation chamber that accommodates the main gas generating agent; a secondary gas generation chamber that is provided in an interior of the main gas generation chamber and accommodates the initiator; and a secondary gas generating agent accommodated in the secondary gas generation chamber.

摘要翻译： 一种小型，重量轻且便宜的气囊发生器，用于安全气囊装置。 根据本发明的用于气囊装置的气体发生器包括：展开启动引发器，其容纳预定量的点火粉末并且通过对车辆的冲击而被激活; 主要气体发生剂，其产生用于在燃烧时使气囊充气的主气体; 主气体发生室，其容纳主气体发生剂; 二次气体生成室，其设置在主气体生成室的内部并容纳起动器; 以及容纳在二次气体生成室中的二次气体发生剂。

公开(公告)号：US06752659B2

公开(公告)日：2004-06-22

申请号：US10078361

申请日：2002-02-21

申请人： Mitsuharu Nakamura ,  Teruo Yokota

发明人： Mitsuharu Nakamura ,  Teruo Yokota

IPC分类号： H01R1340

CPC分类号： H01R13/5219 ,  H01R13/5208

摘要： A waterproof connector is provided with a connector housing having a mating hollow to which an opposing connector is fitted, a seal fitted to an opposite side to the mating hollow of the connector housing, and a rear holder inserted and fitted to the connector housing. The seal is further provided with a plurality of through holes to which cables provided with terminals at front ends are respectively inserted, and the rear holder is provided with insertion holes communicating with the through holes respectively. The rear holder allows the cable to pass through at a time of being inserted to a temporary engaging position, and presses the seal so as to fix at a time of being inserted to a regular engaging position. The insertion holes are extended so as to have a length at a degree at which a front end thereof is not brought into contact with lips of the through holes even when the inserted terminals are inclined. Any one or both of the connector housing and the rear holder is provided with one or more ribs sliding pressure contact with an opposing member, and the rib extends in a fitting and inserting direction of the rear holder.

摘要翻译： 防水连接器设置有连接器壳体，该连接器壳体具有配合的中空件，相对的连接器装配到该中空部件，与连接器壳体的配合中空部相对的一侧装配有密封件，以及插入并安装在连接器壳体上的后部保持件。 密封件还设置有多个通孔，分别插入设置有前端的端子的电缆，后保持器分别设置有与通孔连通的插入孔。 后支架允许电缆在插入到临时接合位置时通过，并且在插入到正常接合位置时按压密封件以固定。 即使插入端子倾斜，插入孔延伸到其前端未与通孔的唇缘接触的程度的长度。 连接器壳体和后保持器中的任一个或两个设置有与相对构件滑动压力接触的一个或多个肋，并且肋沿着后保持器的配合和插入方向延伸。

公开(公告)号：US06558179B2

公开(公告)日：2003-05-06

申请号：US10078415

申请日：2002-02-21

申请人： Mitsuharu Nakamura ,  Teruo Yokota

发明人： Mitsuharu Nakamura ,  Teruo Yokota

IPC分类号： H01R1352

CPC分类号： H01R13/5221 ,  H01R13/4362

摘要： A waterproof connector is constituted by a connector housing provided with a mating hollow to which an opposing connector is fitted and a terminal housing protruded within the mating hollow, a first packing pressure contacted with the opposing connector within the mating hollow so as to be closely attached to a periphery of the terminal housing, and a slide arranged between the terminal housing and the first packing. The connector housing receives a plurality of cables provided with terminals at front ends so as to hold a second packing therebetween. The slide is provided with a plurality of slits being parallel to a sliding direction and respectively inserting the terminals, and a retaining portion extending toward the first packing in one end portion. The slits prevent the terminals from falling off in a side of the retaining portion, and allow the terminals to pass through in an opposite side.

摘要翻译： 防水连接器由连接器壳体构成，该连接器壳体具有配合的中空体，相对的连接器装配到该中空孔中，以及突出于配合空心内的端子壳体，第一密封压力与配合空心内的相对连接器接触，以便紧密连接 到端子壳体的周边，以及布置在端子壳体和第一填料之间的滑块。 连接器壳体容纳在前端设置有端子的多个电缆，以便在其间保持第二填料。 滑动件设置有多个平行于滑动方向的狭缝，并且分别插入端子，以及在一个端部中朝向第一密封件延伸的保持部分。 狭缝防止端子在保持部分的一侧脱落，并且允许端子在相对侧通过。

公开(公告)号：US5679034A

公开(公告)日：1997-10-21

申请号：US674968

申请日：1996-07-03

申请人： Hisashi Hanazaki ,  Mitsuharu Nakamura

发明人： Hisashi Hanazaki ,  Mitsuharu Nakamura

IPC分类号： H01R13/187

CPC分类号： H01R13/187 ,  H01R13/113

摘要： A plurality of retaining piece portions are formed at an edge of a tubular body of a female electrical connection member, and the retaining piece portions are bent to clampingly retain plural portions in one end of a resilient contact piece. As a result, the retaining piece portions can be bent easily, and a crack is prevented from developing at the bent portion. And besides, since the resilient contact piece is fixed by the retaining piece portions at the plurality of portions thereof spaced from one another, stresses, concentrating on the fixed portions of the resilient contact piece, are distributed on the fixed portions, so that permanent set of the resilient contact piece due to deterioration of its resiliency can be prevented.

摘要翻译： 多个保持片部分形成在阴电连接部件的管状体的边缘处，并且保持片部分被弯曲以在弹性接触片的一端中夹紧地保持多个部分。 结果，可以容易地弯曲保持件部分，并且防止在弯曲部分处产生裂纹。 此外，由于弹性接触片在其彼此间隔开的多个部分处由保持片部分固定，集中在弹性接触片的固定部分上的应力分布在固定部分上，使得永久变形 可以防止由于其弹性的劣化而导致的弹性接触片。

公开(公告)号：US09016207B2

公开(公告)日：2015-04-28

申请号：US13145901

申请日：2010-01-21

申请人： Yoji Tasaki ,  Mitsuharu Nakamura ,  Ryutaro Shiraishi ,  Koji Saiki ,  Jianlin Chen

发明人： Yoji Tasaki ,  Mitsuharu Nakamura ,  Ryutaro Shiraishi ,  Koji Saiki ,  Jianlin Chen

IPC分类号： F42B3/02 ,  B60R21/264 ,  F42B3/04 ,  B60R21/263

CPC分类号： B60R21/2644 ,  B60R2021/2633 ,  B60R2021/2648 ,  F42B3/04

摘要： A small, lightweight, and inexpensive gas generator for an airbag device. The gas generator for an airbag device according to the present invention includes: a deployment activating initiator that accommodates a predetermined amount of ignition powder and is activated by an impact on a vehicle; a main gas generating agent that generates a main gas for inflating an airbag when burned; a main gas generation chamber that accommodates the main gas generating agent; a secondary gas generation chamber that is provided in an interior of the main gas generation chamber and accommodates the initiator; and a secondary gas generating agent accommodated in the secondary gas generation chamber.

摘要翻译： 一种小型，重量轻且便宜的气囊发生器，用于安全气囊装置。 根据本发明的用于气囊装置的气体发生器包括：展开启动引发器，其容纳预定量的点火粉末并且通过对车辆的冲击而被激活; 主要气体发生剂，其产生用于在燃烧时使气囊充气的主气体; 主气体发生室，其容纳主气体发生剂; 二次气体生成室，其设置在主气体生成室的内部并容纳起动器; 以及容纳在二次气体生成室中的二次气体发生剂。

公开(公告)号：US20090082311A1

公开(公告)日：2009-03-26

申请号：US12226745

申请日：2007-04-27

申请人： Masatoshi Kiuchi ,  Mitsuharu Nakamura ,  Maiko Hamada ,  Kunio Sugahara

发明人： Masatoshi Kiuchi ,  Mitsuharu Nakamura ,  Maiko Hamada ,  Kunio Sugahara

IPC分类号： A61K31/137 ,  C07C215/20 ,  C07C69/34 ,  C07D317/30 ,  A61P37/00 ,  A61K31/675 ,  A61K31/662 ,  A61K31/216 ,  C07F9/653 ,  A61K31/357

CPC分类号： C07F9/653 ,  C07C217/64 ,  C07C225/16 ,  C07C309/65 ,  C07C323/32 ,  C07C323/38 ,  C07C323/41 ,  C07D333/22 ,  C07D333/34 ,  C07F9/091

摘要： The present invention provides a novel compound having few side effects such as bradycardia and the like and having superior peripheral blood lymphocyte-decreasing effect.The present invention provides a 2-aminobutanol compound represented by the following formula (I) wherein R1 is a hydrogen atom or P(═O) (OH)2, R2 is an alkyl having 1 to 4 carbon atoms optionally substituted by hydroxyl group(s) or optionally substituted by halogen atom(s), R3 is a hydrogen atom; a halogen atom; cyano; an alkyl having 1 to 4 carbon atoms optionally substituted by halogen atom(s); or an acyl having 2 to 5 carbon atoms optionally substituted by halogen atom(s), X is an oxygen atom, a sulfur atom, carbonyl or NR4 wherein R4 is a hydrogen atom or an alkyl having 1 to 4 carbon atoms, Ar1 is an optionally substituted arylene or an optionally substituted heteroarylene, and Ar2 is an optionally substituted aryl or an optionally substituted heteroaryl, provided that when X is an oxygen atom, Ar1 is phenylene and Ar2 is phenyl, then the phenyl for Ar2 should be substituted, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof, as well as a production method of the above-mentioned 2-aminobutanol compound.

摘要翻译： 本发明提供一种副作用少的新型化合物，如心动过缓等，具有优异的外周血淋巴细胞减少作用。 本发明提供由下式（I）表示的2-氨基丁醇化合物，其中R 1为氢原子或P（-O）（OH）2，R 2为任选被羟基取代的具有1至4个碳原子的烷基 或任选被卤素原子取代，R 3是氢原子; 卤素原子; 氰基; 任选被卤素原子取代的碳原子数1〜4的烷基; 或任选被卤素原子取代的具有2至5个碳原子的酰基，X是氧原子，硫原子，羰基或NR 4，其中R 4是氢原子或具有1至4个碳原子的烷基，Ar 1是 任选取代的亚芳基或任选取代的亚杂芳基，Ar 2是任选取代的芳基或任选取代的杂芳基，条件是当X是氧原子时，Ar 1是亚苯基，Ar 2是苯基，则Ar 2的苯基应该被取代，或 其药学上可接受的酸加成盐或其水合物或其溶剂合物，以及上述2-氨基丁醇化合物的制备方法。

公开(公告)号：US5180544A

公开(公告)日：1993-01-19

申请号：US752218

申请日：1991-08-21

申请人： Ritsuo Yoshioka ,  Makoto Ueda ,  Yuichi Motora ,  Mitsuharu Nakamura

发明人： Ritsuo Yoshioka ,  Makoto Ueda ,  Yuichi Motora ,  Mitsuharu Nakamura

IPC分类号： G21C7/113

CPC分类号： G21C7/113 ,  G21Y2002/103 ,  G21Y2002/30 ,  G21Y2002/301 ,  G21Y2004/10 ,  G21Y2004/30 ,  Y02E30/31 ,  Y02E30/39

摘要： In the field of commercial nuclear reactors, there is an increasing demand for long-life control blades in order to meet the requirements of higher economy and reduction in the disposal of radioactive wastes. A control blade proposed by the invention stands a long use by virtue of the use of a long-life neutron absorber which is typically made of hafnium. Despite the use of hafnium which has a large specific weight (13.3 g/cm.sup.3), the size, shape and weight of the control blade are substantially the same as those of conventional control blades which employ boron carbides B.sub.4 C as the neutron absorber, so that the control blade can be back-fitted in existing boiling water reactors without difficulty. The control blade of this invention is a flux-trap-type control blade in which long-life neutron absorber plates or sheets are arranged to oppose each other in the thicknesswise direction of the wing within the sheath plate such that a water gap is preserved between the opposing neutron absorber plates, so that the weight of the hafnium, which occupies most part of the total weight of the control blade, is reduced by an amount corresponding to the volume of the water gap. The thickness of the neutron absorber plates or sheets is increased at the upper portion of the control blade where the neutron exposure is specifically high and where a large neutron absorption power or capacity is required for ensuring a sufficient reactor shut-down margin, while the thickness is reduced in other portions so as to increase the size of the water gap. In consequence, the weight of the control blade incorporating heavy hafnium as the neutron absorber is reduced almost to the same level as that of ordinary control blades, without being accompanied by any reduction in the reactivity worth.

摘要翻译： 在商业核反应堆领域，长寿命控制叶片的需求不断增加，以满足高经济性和放射性废物处理量的减少。 本发明提出的控制叶片由于使用通常由铪制成的长寿命中子吸收器而长期使用。 尽管使用具有大比重（13.3g / cm 3）的铪，但是控制叶片的尺寸，形状和重量与使用硼碳化物B4C作为中子吸收体的常规控制叶片的尺寸，形状和重量基本相同，使得 控制叶片可以毫无困难地回装在现有的沸水反应堆中。 本发明的控制叶片是其中长寿命中子吸收器板或片布置成在鞘板内的机翼的厚度方向上彼此相对的通量捕获型控制叶片，使得在 相反的中子吸收器板，使得占据对照叶片总重量的大部分的铪的重量减少相应于水隙体积的量。 中子吸收板或薄板的厚度在控制叶片的上部增加，其中中子暴露特别高，并且需要大的中子吸收能力或容量以确保足够的反应堆停机裕度，而厚度 在其他部分被减少以增加水隙的尺寸。 因此，将重铪作为中子吸收剂的控制叶片的重量降低到几乎与普通对照叶片相同的水平，而不伴随着反应性价值的降低。

公开(公告)号：US08699652B2

公开(公告)日：2014-04-15

申请号：US12034966

申请日：2008-02-21

申请人： Yuuji Saito ,  Mitsuharu Nakamura ,  Makoto Ueda ,  Yoshinori Katayama ,  Motoji Tsubota ,  Satoko Tajima ,  Yoshiji Karino ,  Kenichi Yoshioka ,  Kosaku Tsumita

发明人： Yuuji Saito ,  Mitsuharu Nakamura ,  Makoto Ueda ,  Yoshinori Katayama ,  Motoji Tsubota ,  Satoko Tajima ,  Yoshiji Karino ,  Kenichi Yoshioka ,  Kosaku Tsumita

IPC分类号： G21C7/06

CPC分类号： G21C7/113 ,  G21C21/18 ,  G21Y2002/206 ,  G21Y2004/30 ,  G21Y2004/40 ,  Y02E30/31 ,  Y02E30/39

摘要： A control rod for nuclear reactors includes four wings including neutron absorbers containing hafnium, a front end structural member which has a cross shape in cross section and includes brackets bonded to the leading ends of the wings, and a terminal end structural member which has a cross shape in cross section and includes brackets bonded to the tailing ends of the wings. The four wings are bonded to a wing-bonding member including a cross-shaped center shaft so as to form a cross shape. The front end structural member and the wing-bonding member are made of a zirconium alloy. The wings include neutron-absorbing plates having neutron-absorbing portions and each have an outer surface which is opposed to a fuel assembly and at which a hafnium-zircaloy composite member covered with zircaloy is disposed. The neutron-absorbing plates are opposed to each other with trap spaces disposed therebetween.

摘要翻译： 用于核反应堆的控制棒包括四个翼，包括含有铪的中子吸收体，前端结构构件的截面十字形，并且包括结合到翼的前端的支架，以及具有十字形的末端结构构件 并且包括结合到翼的尾端的支架。 四个翼结合到包括十字形中心轴的翼接合构件以形成十字形状。 前端结构构件和翼缘接合构件由锆合金制成。 机翼包括具有中子吸收部分的中子吸收板，并且每个都具有与燃料组件相对的外表面，并且设置有用锆石覆盖的铪 - 氧化锆复合材料构件。 中子吸收板彼此相对，在它们之间设置有捕获空间。