公开(公告)号：US20120040908A1

公开(公告)日：2012-02-16

申请号：US13129613

申请日：2009-10-19

申请人： Mizuho Kido ,  Toshiyuki Watanabe ,  Atsushi Danjo ,  Teruo Tanaka ,  Daisuke Uetsuji ,  Aiko Ono ,  Atsushi Serizawa

发明人： Mizuho Kido ,  Toshiyuki Watanabe ,  Atsushi Danjo ,  Teruo Tanaka ,  Daisuke Uetsuji ,  Aiko Ono ,  Atsushi Serizawa

IPC分类号： A61K38/17 ,  A61P19/00 ,  A61P19/08

CPC分类号： A61K35/20 ,  A21D2/263 ,  A23C19/082 ,  A23J1/20 ,  A23K20/147 ,  A23L33/18 ,  A23L33/19 ,  A23V2002/00 ,  A61K38/018 ,  A23V2200/306

摘要： Disclosed is a substance capable of promoting the repair of a fractured part in a fracture caused by an external force, fatigue or a disease. Also disclosed is a method for producing the substance. Further disclosed is a product capable of promoting the repair of a fracture, such as a food, a beverage and a feed, which comprises the fracture repair promoter. Specifically disclosed is a fracture repair promoter comprising, as an active ingredient, a fraction containing a milk-derived basic protein. In the promoter, the fraction containing the milk-derived basic protein is produced by contacting milk or a milk-derived raw material with a cation exchange resin to cause the adsorption of the basic protein on the cation exchange resin and eluting a fraction adsorbed on the resin by means of an eluent having a salt concentration of 0.1 to 1.0 M.

摘要翻译： 公开了能够促进由外力，疲劳或疾病引起的骨折部位的修复的物质。 还公开了一种生产该物质的方法。 进一步公开的是能够促进骨折的修复的产品，例如包含骨折修复促进剂的食品，饮料和饲料。 具体公开了一种骨折修复促进剂，其包含含有乳源性碱性蛋白质的级分作为活性成分。 在促进剂中，含有乳衍生的碱性蛋白质的级分通过使乳或乳衍生的原料与阳离子交换树脂接触而产生，以使碱性蛋白质吸附在阳离子交换树脂上并洗脱吸附在 树脂，通过盐浓度为0.1〜1.0M的洗脱液。