公开(公告)号：US20110113813A1

公开(公告)日：2011-05-19

申请号：US13009924

申请日：2011-01-20

申请人： Myung Ryul LEE ,  Seong Jae KIM ,  Chang Ho SEO ,  Sung Hoon CHUNG

发明人： Myung Ryul LEE ,  Seong Jae KIM ,  Chang Ho SEO ,  Sung Hoon CHUNG

IPC分类号： F25C5/18 ,  F25D11/02

CPC分类号： F25C5/046 ,  F25C1/04 ,  F25C2400/10 ,  F25D17/065 ,  F25D23/087 ,  F25D2317/061 ,  F25D2317/062 ,  F25D2317/0666 ,  F25D2317/0682 ,  F25D2317/0683 ,  F25D2400/04 ,  F25D2400/06 ,  F25D2500/02

摘要： Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

公开(公告)号：US07888118B2

公开(公告)日：2011-02-15

申请号：US12749922

申请日：2010-03-30

申请人： In-Jae Shin ,  Myung-Ryul Lee ,  Darren Williams

发明人： In-Jae Shin ,  Myung-Ryul Lee ,  Darren Williams

IPC分类号： C12N5/00

CPC分类号： C07D405/04 ,  C07D233/64

摘要： The present invention relates to 4,5-bis(4-methoxyphenyl)imidazole compound inducing differentiation of myoblasts or muscle fibers into neuron cells, a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation. More specifically, it relates to 2-{2-[5-(3-chlorophenyl)]furanyl}-4,5-bis(4-methoxyphenyl)imidazole that induces differentiation of myoblasts or muscle fibers into neuron cells, all pharmaceutically acceptable isomers, salts, and a pharmaceutical composition including said compound, a method of inducing neuron cells differentiation and a screening method for identifying additional compound useful for inducing neuron cells differentiation.

摘要翻译： 本发明涉及诱导成肌细胞或肌纤维分化为神经元细胞的4,5-双（4-甲氧基苯基）咪唑化合物，包含所述化合物的药物组合物，诱导神经元细胞分化的方法和鉴定另外的化合物的筛选方法 可用于诱导神经细胞分化。 更具体地说，它涉及诱导成肌细胞或肌纤维分化成神经细胞的2- {2- [5-（3-氯苯基）]呋喃基} -4,5-双（4-甲氧基苯基）咪唑，所有药学上可接受的异构体 盐，以及包含所述化合物的药物组合物，诱导神经元细胞分化的方法以及鉴定用于诱导神经元细胞分化的其它化合物的筛选方法。

公开(公告)号：US20100105726A1

公开(公告)日：2010-04-29

申请号：US12528680

申请日：2007-02-26

申请人： In-Jae Shin ,  Myung-ryul Lee ,  Darren Williams

发明人： In-Jae Shin ,  Myung-ryul Lee ,  Darren Williams

IPC分类号： A61K31/4178 ,  C12Q1/06 ,  C40B30/06 ,  A61K31/4725 ,  C07D401/04 ,  C07D405/06 ,  C07D403/06 ,  C07D233/61 ,  A61P35/00

CPC分类号： C07D233/64

摘要： The present invention relates to a pharmaceutical composition comprising compound for induction of apoptosis, a method for inducing cancer cell apoptosis, a method to suppress lymphocyte activation, a method to improve intracellular trafficking of misfolded mutants and a screening method to identify additional compounds useful for inducing apoptosis, and more specifically, it relates to pharmaceutical compositions comprising imidazole derivatives as active gradients for induction of apoptosis to treat various diseases including cancers and immune-related diseases, the method of inducing apoptosis by treating cancer cells with the said pharmaceutical composition, the method of inactivating human lymphocytes by treating lymphocytes with the said pharmaceutical composition, the method of improving intracellular trafficking of misfolded mutants by treating cells containing the mutants with the said pharmaceutical composition, and the screening method for identifying additional compound useful for inducing apoptosis, wherein cells are incubated with the said pharmaceutical composition and detected.

摘要翻译： 本发明涉及包含用于诱导凋亡的化合物的药物组合物，诱导癌细胞凋亡的方法，抑制淋巴细胞活化的方法，改善错误折叠的突变体的细胞内运输的方法以及鉴定用于诱导的另外的化合物的筛选方法 更具体地，涉及包含咪唑衍生物作为用于诱导凋亡以用于治疗各种疾病（包括癌症和免疫相关疾病）的活性梯度的药物组合物，通过用所述药物组合物治疗癌细胞诱导凋亡的方法，该方法 通过用所述药物组合物处理淋巴细胞来灭活人淋巴细胞，通过用所述药物组合物处理含有突变体的细胞来改善错误折叠突变体的细胞内运输的方法，以及用于鉴定另外的化合物用途的筛选方法 用于诱导细胞凋亡，其中细胞与所述药物组合物一起孵育并检测。

公开(公告)号：US07654105B2

公开(公告)日：2010-02-02

申请号：US12133978

申请日：2008-06-05

申请人： Myung Ryul Lee ,  Seong Jae Kim ,  Chang Ho Seo ,  Sung Hoon Chung

发明人： Myung Ryul Lee ,  Seong Jae Kim ,  Chang Ho Seo ,  Sung Hoon Chung

IPC分类号： F25C5/18

CPC分类号： F25C5/046 ,  F25C1/04 ,  F25C2400/10 ,  F25D17/065 ,  F25D23/087 ,  F25D2317/061 ,  F25D2317/062 ,  F25D2317/0666 ,  F25D2317/0682 ,  F25D2317/0683 ,  F25D2400/04 ,  F25D2400/06 ,  F25D2500/02

摘要： Refrigerator with an icemaker including a cabinet having a mullion wall for compartmentalization of a freezing chamber and a refrigerating chamber, a case provided to a door on the refrigerating chamber, having a cavity therein, a first duct for supplying cold air from a neighborhood of an evaporator in the freezing chamber to the cavity, the icemaker in the cavity for producing ice, an ice container in the cavity for storing the ice, and a dispenser in the door in communication with the cavity, thereby having ice supplied to a user at an outside of the refrigerator through a dispenser provided to the door.

摘要翻译： 具有制冰机的冰箱包括具有用于分隔冷冻室和冷藏室的竖框壁的柜体，设置在其上具有空腔的冷藏室门上的壳体，用于从冷冻室的附近供应冷空气的第一管道 在冷冻室中的蒸发器到空腔，用于产生冰的空腔中的制冰机，用于存储冰的空腔中的冰容器和与腔连通的门中的分配器，从而在冰中向用户提供冰 通过提供给门的分配器在冰箱之外。

公开(公告)号：US20080041088A1

公开(公告)日：2008-02-21

申请号：US11843475

申请日：2007-08-22

申请人： Myung Ryul Lee ,  Sung Chung ,  Seong Kim ,  Chang Seo

发明人： Myung Ryul Lee ,  Sung Chung ,  Seong Kim ,  Chang Seo

IPC分类号： F25C1/22

CPC分类号： F25D17/065 ,  F25C1/00 ,  F25C5/22 ,  F25C2400/10 ,  F25D17/045 ,  F25D23/04 ,  F25D23/12 ,  F25D2317/062 ,  F25D2317/0664 ,  F25D2317/0671 ,  F25D2317/0672 ,  F25D2400/04

摘要： A refrigerator is provided with an airflow passage for an ice making compartment of the refrigerator. In the refrigerator, a main body has an opened side, and a door selectively closes the opened side of the main body. An ice making compartment is formed in the door, the ice making compartment being insulated from the outside and being kept at a low temperature. A duct is formed in the main body for exchanging cooling air with the ice making compartment, and a cooling air passage is formed at an outer surface of the ice making compartment to connect the duct with the ice making compartment. A switching unit closes the cooling air passage when the door is opened, and opens the cooling air passage when the door is closed. With this arrangement, the cooling air can be sufficiently supplied to the ice making compartment without the penetration of foreign substance.

摘要翻译： 冰箱设置有用于冰箱的制冰室的气流通道。 在冰箱中，主体具有开口侧，门选择性地关闭主体的开口侧。 制冰室形成在门上，制冰室与外界隔绝并保持在低温。 在主体中形成用于与制冰室交换冷却空气的管道，并且在制冰室的外表面处形成冷却空气通道，以将管道与制冰室连接。 当门打开时，切换单元关闭冷却空气通道，并且当门关闭时打开冷却空气通道。 利用这种布置，可以将冷却空气充分地供应到制冰室而不会渗入异物。

公开(公告)号：US07263854B2

公开(公告)日：2007-09-04

申请号：US11337585

申请日：2006-01-24

申请人： Wook Yong Lee ,  Myung Ryul Lee ,  Seung Hwan Oh ,  Eui Yeop Chung

发明人： Wook Yong Lee ,  Myung Ryul Lee ,  Seung Hwan Oh ,  Eui Yeop Chung

IPC分类号： F25C1/12

CPC分类号： F25C1/04 ,  F25C5/046 ,  F25C5/182 ,  F25C5/22 ,  F25C2400/04 ,  F25C2400/10 ,  F25C2500/06 ,  F25C2600/04 ,  F25C2700/06

摘要： An icemaker for an ice supply system for preventing water from overflowing from the ice tray by vibration and/or shaking of the surrounding structure includes an icemaker, a container provided at a lower part of the icemaker and an ice chute for supplying the ice stored in the ice container. An ejector in the ice tray of the icemaker and a dropper device having an inclined upper surface at a side of the open top of the ice tray are provided for dropping the ice discharged upwardly by the ejector. The dropper has no gap or slot through which the ejector passes to prevent water overflow through the dropper. An overflow prevention device is provided at another side of the open top of the ice tray for preventing water filled in the ice tray from overflowing.

摘要翻译： 一种用于防止水从周围结构的振动和/或晃动而使水从冰盘溢出的制冰机的制冰机包括制冰机，设在制冰机下部的容器和用于供应储存在冰箱中的冰的冰槽 冰箱。 在制冰机的冰盘中的喷射器和在冰盘的开口顶部的一侧具有倾斜的上表面的滴管装置被设置用于将由喷射器向上排放的冰滴下。 滴管没有间隙或槽，喷射器通过该间隙或槽，以防止水通过滴管溢出。 在冰盘的开口顶部的另一侧设置溢流防止装置，以防止填充在冰盘中的水溢出。

公开(公告)号：US07240512B2

公开(公告)日：2007-07-10

申请号：US11043972

申请日：2005-01-28

申请人： Wook Yong Lee ,  Eui Yeop Chung ,  Seung Hwan Oh ,  Myung Ryul Lee ,  Ill Shin Kim ,  Seong Ook Kim ,  Yong Chol Kwon

发明人： Wook Yong Lee ,  Eui Yeop Chung ,  Seung Hwan Oh ,  Myung Ryul Lee ,  Ill Shin Kim ,  Seong Ook Kim ,  Yong Chol Kwon

IPC分类号： F25C1/12

CPC分类号： F25D23/126 ,  F25C1/04 ,  F25C5/22 ,  F25C2400/10 ,  F25D17/065 ,  F25D23/04 ,  F25D23/087 ,  F25D2317/062 ,  F25D2317/0664 ,  F25D2317/0666 ,  F25D2400/06

摘要： Provided is a refrigerator including an adiabatic space formed on an inner surface of a chilling chamber door and an ice machine disposed inside the adiabatic space, thereby enabling a more efficient usage of an inner space of the refrigerator. Also, the present invention provides a cooling air passage structure of a refrigerator for properly supplying cooling air for freezing to an inside of the refrigerator having an ice machine disposed on an inner surface of a chilling chamber door.

摘要翻译： 本发明提供一种冰箱，其包括形成在冷藏室门的内表面上的绝热空间和设置在绝热空间内的制冰机，能够更有效地利用冰箱的内部空间。 此外，本发明提供一种用于将冷冻冷却空气适当地供给到具有设置在冷藏室门的内表面上的制冰机的冰箱内部的冷藏库的冷却空气通道结构。

公开(公告)号：US07051541B2

公开(公告)日：2006-05-30

申请号：US10814229

申请日：2004-04-01

申请人： Eui Yeop Chung ,  Wook Yong Lee ,  Seung Hwan Oh ,  Myung Ryul Lee

发明人： Eui Yeop Chung ,  Wook Yong Lee ,  Seung Hwan Oh ,  Myung Ryul Lee

IPC分类号： F25C5/08

CPC分类号： F25C1/04 ,  F25C5/185 ,  F25C5/22 ,  F25C2400/10 ,  F25C2500/06 ,  F25C2700/06

摘要： Icemaker in a refrigerator for making ice automatically is disclosed. The icemaker in includes an ice tray provided to a door on the refrigerator for holding water, an ejector fitted adjacent to the ice tray so as to be rotatable by a motor for ejecting ice from the ice tray, means for detecting a rotation angle of the ejector, and a control part for controlling a rotation direction of the ejector based on information detected at the means.

摘要翻译： 自动制冰的冰箱制冰机被公开。 制冰机包括设置在冰箱上的用于保持水的门的冰盘，与冰托相邻的喷射器，以便通过用于从冰盘排出冰的电动机旋转，用于检测所述冰盘的旋转角度的装置 喷射器和控制部件，用于根据装置检测到的信息控制喷射器的旋转方向。

公开(公告)号：US07017363B2

公开(公告)日：2006-03-28

申请号：US10776535

申请日：2004-02-12

申请人： Myung Ryul Lee ,  Wook Yong Lee ,  Eui Yeop Chung ,  Seung Hwan Oh

发明人： Myung Ryul Lee ,  Wook Yong Lee ,  Eui Yeop Chung ,  Seung Hwan Oh

IPC分类号： F25C5/04

CPC分类号： F25C5/185 ,  F25C1/04 ,  F25C5/046 ,  F25C5/22 ,  F25C2400/10 ,  Y10S241/17

摘要： An ice supply system of a refrigerator is provided. The ice supply system of the refrigerator includes an icemaker, a container, a crusher and an ice discharger. The icemaker produces the ice by using cool air of the freezer and drops the ice to a lower part of thereof. The container is provided at a lower part of the icemaker. The container is insertable into and detachable from the door of the refrigerator. The container includes an open top, a first opening at a side thereof, a transfer device rotating and transferring the ice of the first opening, and an outlet for discharging the ice. The crusher crushes the ice transferred by the transfer device and the ice discharger is provided for discharging the ice to an ice chute at the door by controlling a size of an opening of the outlet.

摘要翻译： 提供冰箱的供冰系统。 冰箱的供冰系统包括制冰机，容器，破碎机和排冰机。 制冰机通过使用冷冻机的冷空气产生冰，并将冰滴到其下部。 容器设置在制冰机的下部。 容器可插入冰箱的门并可从冰箱的门拆卸。 容器包括敞开的顶部，在其一侧的第一开口，旋转并传送第一开口的冰的传送装置和用于排出冰的出口。 破碎机粉碎由传送装置传送的冰，并且提供排冰器，用于通过控制出口的开口的尺寸将冰排出到门上的冰槽。

公开(公告)号：US07017354B2

公开(公告)日：2006-03-28

申请号：US10847368

申请日：2004-05-18

申请人： Myung Ryul Lee ,  Seong Jae Kim

发明人： Myung Ryul Lee ,  Seong Jae Kim

IPC分类号： F25C5/08

CPC分类号： F25C1/20 ,  F25C1/04 ,  F25C2400/10 ,  F25C2500/02 ,  F25C2500/06 ,  F25D2400/30

摘要： Disclosed is a quick ice-making control method of an ice-maker for a refrigerator, in which an ejector for extracting obtained ice stirs supplied water to be frozen so as to promote thermal transmission of the water. The quick ice-making control method includes the steps of (a) supplying water into an ice-maker mold, (b) quickly freezing the water by rotating an ejector for a predetermined time after the step (a), and (c) separating the obtained ice from the ice-maker mold in case that a temperature of the ice-maker mold is lower than a predetermined temperature after the step (b).

摘要翻译： 公开了一种用于冰箱的制冰机的快速制冰控制方法，其中用于提取所获得的冰的喷射器搅动供应的待冷冻水以促进水的热传递。 快速制冰控制方法包括以下步骤：（a）将水供应到制冰机模具中，（b）在步骤（a）之后通过旋转喷射器预定时间快速冷冻水，和（c）分离 在制冰模具的温度低于步骤（b）之后的预定温度的情况下，从制冰机模具获得的冰。