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公开(公告)号:US08828951B2
公开(公告)日:2014-09-09
申请号:US13614534
申请日:2012-09-13
申请人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
发明人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
IPC分类号: A61K31/70
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运体(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US20140274921A1
公开(公告)日:2014-09-18
申请号:US14291268
申请日:2014-05-30
申请人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
发明人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
IPC分类号: C07H7/04
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US08466114B2
公开(公告)日:2013-06-18
申请号:US13425888
申请日:2012-03-21
申请人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
发明人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US08163704B2
公开(公告)日:2012-04-24
申请号:US12906682
申请日:2010-10-18
申请人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
发明人: Gregory Raymond Bebernitz , Mark G. Bock , Dumbala Srinivas Reddy , Atul Kashinath Hajare , Vinod Vyavahare , Sandeep Bhausaheb Bhosale , Suresh Eknath Kurhade , Videsh Salunkhe , Nadim S. Shaikh , Debnath Bhuniya , P. Venkata Palle , Lili Feng , Jessica Liang
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US20110171159A1
公开(公告)日:2011-07-14
申请号:US12906682
申请日:2010-10-18
申请人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
发明人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
IPC分类号: A61K31/785 , C07H7/06 , A61K31/706 , A61K31/7048 , A61K38/28 , A61K38/26 , A61P3/00 , A61P9/12
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US20130017993A1
公开(公告)日:2013-01-17
申请号:US13614534
申请日:2012-09-13
申请人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
发明人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
IPC分类号: A61K31/706 , A61K31/7048 , A61K38/28 , A61P9/12 , A61P3/10 , A61P3/00 , A61P3/04 , C07H7/06 , A61K31/7056
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
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公开(公告)号:US20150141354A1
公开(公告)日:2015-05-21
申请号:US14604173
申请日:2015-01-23
申请人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
发明人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
IPC分类号: A61K31/7048 , A61K31/706
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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公开(公告)号:US20120178680A1
公开(公告)日:2012-07-12
申请号:US13425888
申请日:2012-03-21
申请人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
发明人: Gregory Raymond BEBERNITZ , Mark G. BOCK , Dumbala Srinivas REDDY , Atul Kashinath HAJARE , Vinod VYAVAHARE , Sandeep Bhausaheb BHOSALE , Suresh Eknath KURHADE , Videsh SALUNKHE , Nadim S. SHAIKH , Debnath BHUNIYA , P. Venkata PALLE , Lili FENG , Jessica LIANG
IPC分类号: A61K31/7034 , A61P3/04 , A61P3/10 , A61K38/28 , A61P3/00
CPC分类号: A61K31/7052 , A61K31/7048 , A61K31/706 , C07D405/10 , C07D407/10 , C07D413/10 , C07H7/04
摘要: This invention relates to compounds represented by formula (I): wherein the variables are defined as herein above, which are useful for treating diseases and conditions mediated by the sodium D-glucose co-transporter (SGLT), e.g. diabetes. The invention also provides methods of treating such diseases and conditions, and compositions etc. for their treatment.
摘要翻译: 本发明涉及由式(I)表示的化合物:其中变量如上文所定义,其可用于治疗D-葡萄糖共转运蛋白(SGLT)介导的疾病和病症,例如, 糖尿病。 本发明还提供了治疗这些疾病和病症以及组合物等的治疗方法。
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