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公开(公告)号:US10588822B2
公开(公告)日:2020-03-17
申请号:US15722523
申请日:2017-10-02
发明人: Jingxu Zhu , Yingliang Ma , Qingliang Yang , Yunhan Zhang
IPC分类号: A61J3/00 , A61J3/07 , B01F5/20 , A23G3/20 , B05C3/08 , A23G3/26 , B01J2/12 , B01J2/14 , B05B13/02 , B01J2/00 , B05C9/14
摘要: An apparatus for coating pharmaceutical particles such as drug dosage forms or pellets is provided which includes a drum assembly mounted for rotation about a cylindrical axis of the drum and which includes an outer drum section and an inner perforated drum section mounted concentrically on an interior of the outer drum section such that an annular chamber is formed between the perforated inner drum section and the outer drum section. Two or more baffle plates are attached between an outer surface of the inner perforated drum and an inner surface of the outer drum which are configured to act as baffles to restrain or regulate the flow of air which define two or more compartments depending on the number of baffle plates. One end of the drum assembly includes an end plate with a central aperture for use in loading pellets into the drum and provide access to coating constituents that are pumped into the drum interior during the coating process. An air distribution plate is attached at the other end of the drum and has air flow passageways and is interfaced with an air introduction plate having air inlet and outlet passageways. As the drum rotates the air flow passageways in the distribution plate alternately come into flow communication with the air inlet and outlet passageways in the air introduction plate thereby providing a flow path of air into the perforate inner drum and out of the drum assembly.
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公开(公告)号:US20190389785A1
公开(公告)日:2019-12-26
申请号:US16030209
申请日:2018-07-09
发明人: Qingliang Yang , Yingliang Ma , Jingxu Zhu , Kaiqi Shi
IPC分类号: C05G3/00 , C05C11/00 , C09D101/04 , C09D133/10 , C09D7/63 , C09D7/61
摘要: The present disclosure provides a product of coated nutrients for controlled release, a method for coating the nutrients for controlled release and a coating composition for coating the nutrients for controlled release.
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公开(公告)号:US20220062946A1
公开(公告)日:2022-03-03
申请号:US17525068
申请日:2021-11-12
发明人: JIE DONG , JINGXU ZHU , QINGLIANG YANG , YINGLIANG MA , KAIQI SHI , HANG ZHOU , SHOUYUN ZHOU
摘要: A dry powder coating apparatus for coating pharmaceutical solid dosage forms includes a housing; a drum coater; a powder coating system; a liquid spray system; a ventilation system; a heating system; a touch screen control panel; and an operation box. The drum coater may have a truncated cone on both sides, in which one side is opened and another side is closed. The drum coater is horizontally placed inside the operation box along its axis and fixed on a rotatable shaft and a motor drives the rotatable shaft and rotates the drum coater about its own axis.
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公开(公告)号:US20200222330A1
公开(公告)日:2020-07-16
申请号:US16823768
申请日:2020-03-19
发明人: Jingxu Zhu , Yingliang Ma , Qingliang Yang , Kwok Yui Chow , Herman C. Lam
摘要: The present disclosure provides a process of producing a dry powder coated pharmaceutical capsule. The method includes preparing a dry powder film forming polymer coating composition to be coated onto an outer surface of the capsules, a size of the particulate coating powder being in a range from about 1 nm to about 500 μm. The capsules are placed into an interior of a rotatable housing and may be preheated. The dry powder coating composition is sprayed into the interior of the housing while the rotatable housing is rotating to produce a uniform coating of the dry powder coating composition on the outer surface of the capsules. The coated capsules are cured form a substantially uniform cured.
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公开(公告)号:US20200298271A1
公开(公告)日:2020-09-24
申请号:US16519294
申请日:2019-07-23
发明人: JIE DONG , JINGXU ZHU , QINGLIANG YANG , YINGLIANG MA , KAIQI SHI , HANG ZHOU , SHOUYUN ZHOU
摘要: A dry powder coating apparatus for coating pharmaceutical solid dosage forms includes a housing; a drum coater; a powder coating system; a liquid spray system; a ventilation system; a heating system; a touch screen control panel; and an operation box. The drum coater may have a truncated cone on both sides, in which one side is opened and another side is closed. The drum coater is horizontally placed inside the operation box along its axis and fixed on a rotatable shaft and a motor drives the rotatable shaft and rotates the drum coater about its own axis.
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