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    IMPLANTABLE REPAIR DEVICE
    4.
    发明申请
    IMPLANTABLE REPAIR DEVICE 有权
    可植入维修设备

    公开(公告)号：US20140277452A1

    公开(公告)日：2014-09-18

    申请号：US14351952

    申请日：2012-10-18

    申请人： ORTHOX LIMITED

    发明人： Nicholas Skaer

    IPC分类号： A61F2/30

    CPC分类号： A61F2/30756 ,  A61F2002/30757 ,  A61L27/227 ,  A61L27/56 ,  A61L2430/06

    摘要： An implantable repair device for the repair, augmentation or replacement of tissue, uses silk fibroin and has a smooth surface and a porous surface. The smooth surface has a measured Sa value of less than approximately 0.1 μm when using Atomic Force Microscopy when samples of the repair device are fully hydrated by imaging through fluid in peak force tapping mode. A method of preparing such an implantable repair device includes preparing a gel from a fibroin solution in a mould, preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, and creating at least a porous surface on the device, wherein a portion of the mould is adapted to provide at least one smooth surface.

    摘要翻译： 用于修复，增加或更换组织的植入式修复装置使用丝素蛋白，并具有光滑的表面和多孔表面。 当使用原子力显微镜时，光滑表面具有小于约0.1μm的测量值，当修补装置的样品通过在峰值强力攻丝模式下通过流体成像而完全水合时。 制备这种可植入修复装置的方法包括从模具中的丝心蛋白溶液制备凝胶，通过使凝胶进行一个或多个步骤来冻结和解冻凝胶，并在该装置上产生至少多孔表面来制备材料 ，其中所述模具的一部分适于提供至少一个光滑表面。

    Implantable repair device
    6.
    发明授权
    Implantable repair device 有权

    公开(公告)号：US09943412B2

    公开(公告)日：2018-04-17

    申请号：US14351952

    申请日：2012-10-18

    申请人： ORTHOX LIMITED

    发明人： Nicholas Skaer

    IPC分类号： A61L27/56 ,  A61F2/30 ,  A61L27/22

    CPC分类号： A61F2/30756 ,  A61F2002/30757 ,  A61L27/227 ,  A61L27/56 ,  A61L2430/06

    摘要： An implantable repair device for the repair, augmentation or replacement of tissue, uses silk fibroin and has a smooth surface and a porous surface. The smooth surface has a measured Sa value of less than approximately 0.1 μm when using Atomic Force Microscopy when samples of the repair device are fully hydrated by imaging through fluid in peak force tapping mode. A method of preparing such an implantable repair device includes preparing a gel from a fibroin solution in a mold, preparing a material by subjecting the gel to one or more steps of freezing and thawing the gel, and creating at least a porous surface on the device, wherein a portion of the mold is adapted to provide at least one smooth surface.