公开(公告)号：US20180333363A1

公开(公告)日：2018-11-22

申请号：US15980003

申请日：2018-05-15

申请人： Owen Murray

发明人： Owen Murray

IPC分类号： A61K9/28 ,  A61K9/20

CPC分类号： A61K9/2893 ,  A61K9/0056 ,  A61K9/2059 ,  A61K9/2063 ,  A61K9/286 ,  A61K9/2873 ,  A61K31/00

摘要： The present disclosure is directed to compositions and methods for the production of a fast dissolving tablets to be used for the delivery of an agent. An agent can be an active pharmaceutical agent or a non-pharmacological agent, which is needed to be delivered by means of a fast dissolving delivery system. The invention solves many industry challenges within the field of fast dissolve technologies, specifically coupling of fast dissolve properties with required physical attributes of strength/robustness required for commercial production and distribution.

公开(公告)号：US06709669B1

公开(公告)日：2004-03-23

申请号：US09959018

申请日：2001-10-16

申请人： Owen Murray ,  Michael Hall ,  Patrick Kearney ,  Richard Green

发明人： Owen Murray ,  Michael Hall ,  Patrick Kearney ,  Richard Green

IPC分类号： A61K964

CPC分类号： A61K9/2063 ,  A61K9/0056 ,  A61K47/42

摘要： The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing dosage form designed to release the active ingredient rapidly on contact with a fluid. In one embodiment, the composition is designed for oral administration and releases the active ingredient rapidly in the oral cavity on contact with saliva. The fish gelatin can be obtained from cold water fish sources and is preferably the non-gelling, non-hydrolyzed form. A process for preparing such a composition and a method of using fish gelatin in a fast dispersing dosage form are also provided.

公开(公告)号：US20200146993A1

公开(公告)日：2020-05-14

申请号：US16689746

申请日：2019-11-20

申请人： Owen Murray

发明人： Owen Murray

IPC分类号： A61K9/28 ,  A61K31/00 ,  A61K9/00 ,  A61K9/20

摘要： The present disclosure is directed to compositions and methods for the production of a fast dissolving tablets to be used for the delivery of an agent. An agent can be an active pharmaceutical agent or a non-pharmacological agent, which is needed to be delivered by means of a fast dissolving delivery system. The invention solves many industry challenges within the field of fast dissolve technologies, specifically coupling of fast dissolve properties with required physical attributes of strength/robustness required for commercial production and distribution.

公开(公告)号：US09717681B2

公开(公告)日：2017-08-01

申请号：US10534117

申请日：2003-11-03

申请人： Susan Banbury ,  Päivi Juujärvi ,  Leon Grother ,  Walter Lunsmann ,  Owen Murray ,  Juha-Matti Savola

发明人： Susan Banbury ,  Päivi Juujärvi ,  Leon Grother ,  Walter Lunsmann ,  Owen Murray ,  Juha-Matti Savola

IPC分类号： A61K9/20 ,  A61K31/4164 ,  A01N43/50 ,  A61K9/00 ,  A61K47/26 ,  A61K47/42

CPC分类号： A61K9/0056 ,  A61K9/006 ,  A61K9/2095 ,  A61K31/4164 ,  A61K47/26 ,  A61K47/42

摘要： Improved formulations containing substituted imidazole derivatives of the general formula 1, formula (I) wherein Y is —CH2— or —CO—, R1 is H, halo or hydroxy, R2 is H or halo, and R3 is H or lower alkyl (e.g. C1 to C4 alkyl, preferably C1 or C2 alkyl), or a pharmaceutically acceptable salt, such as an acid addition salt, e.g. the hydrochloride, of a compound of the general formula (I), are in solid fast-dispersing dosage form suitable for pre-gastric absorption.

公开(公告)号：US10828261B2

公开(公告)日：2020-11-10

申请号：US16689746

申请日：2019-11-20

申请人： Owen Murray

发明人： Owen Murray

IPC分类号： A61K9/28 ,  A61K31/00 ,  A61K9/00 ,  A61K9/20

摘要： The present disclosure is directed to compositions and methods for the production of a fast dissolving tablets to be used for the delivery of an agent. An agent can be an active pharmaceutical agent or a non-pharmacological agent, which is needed to be delivered by means of a fast dissolving delivery system. The invention solves many industry challenges within the field of fast dissolve technologies, specifically coupling of fast dissolve properties with required physical attributes of strength/robustness required for commercial production and distribution.

公开(公告)号：US2694439A

公开(公告)日：1954-11-16

申请号：US23340451

申请日：1951-06-25

申请人： OWEN MURRAY RONALD

发明人： OWEN MURRAY RONALD

IPC分类号： A47C1/08 ,  A61G15/08

CPC分类号： A61G15/08 ,  A47C1/06 ,  A47C1/08

摘要： 679,304. Dental &c. chairs. MURRAY, R. O. June 21, 1951.. [June 27, 1950] No. 15995/50. Class 52 (ii). A stool or like seat for use with, or combined with, a dental or barber's chair comprises a stool G mounted on a pillar F forming part of a horizontal arm E pivoted on the end of another horizontal arm D 1 which is pivoted about a vertical axis adjacent to the dental chair, footrests also being provided. As shown the vertical pivot C of the arm D' is carried by a bracket A', A 2 secured to the base A of the chair and a foot plate J 1 , with which may be associated the usual switch for appropriately moving the chair into desired position, for one of the feet of the dentist &c. is provided. A rest L 1 comprising a rail mounted on the chair or floor is provided for the dentist's other foot. The stool seat 9 is adjustable upon the pillar F and is provided with a clamp G' for securing it in adjusted height. The arms E, D 1 are preferably urged towards each other by a spring H.

公开(公告)号：US10517834B2

公开(公告)日：2019-12-31

申请号：US15980003

申请日：2018-05-15

申请人： Owen Murray

发明人： Owen Murray

IPC分类号： A61K9/28 ,  A61K9/20 ,  A61K9/00 ,  A61K31/00

摘要： The present disclosure is directed to compositions and methods for the production of a fast dissolving tablets to be used for the delivery of an agent. An agent can be an active pharmaceutical agent or a non-pharmacological agent, which is needed to be delivered by means of a fast dissolving delivery system. The invention solves many industry challenges within the field of fast dissolve technologies, specifically coupling of fast dissolve properties with required physical attributes of strength/robustness required for commercial production and distribution.

公开(公告)号：US09192580B2

公开(公告)日：2015-11-24

申请号：US10685728

申请日：2003-10-14

申请人： Richard Green ,  Owen Murray ,  Michael Hall ,  Patrick Kearney

发明人： Richard Green ,  Owen Murray ,  Michael Hall ,  Patrick Kearney

IPC分类号： A61K9/20 ,  A61K9/00 ,  A61K47/42

CPC分类号： A61K9/2063 ,  A61K9/0056 ,  A61K47/42

摘要： The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing dosage form designed to release the active ingredient rapidly on contact with a fluid. In one embodiment, the composition is designed for oral administration and releases the active ingredient rapidly in the oral cavity on contact with saliva. The fish gelatin can be obtained from cold water fish sources and is preferably the non-gelling, non-hydrolyzed form. A process for preparing such a composition and a method of using fish gelatin in a fast dispersing dosage form are also provided.

摘要翻译： 本文公开的本发明涉及包含载体和活性成分的药物组合物，其中所述载体是鱼明胶，并且所述组合物是快速分散剂型，其设计为在与流体接触时快速释放活性成分。 在一个实施方案中，组合物被设计用于口服给药，并且在与唾液接触时在口腔中快速释放活性成分。 鱼明胶可以从冷水鱼源获得，优选非胶凝，非水解形式。 还提供了制备这种组合物的方法和以快速分散剂型使用鱼明胶的方法。

公开(公告)号：US20060134194A1

公开(公告)日：2006-06-22

申请号：US10534117

申请日：2003-11-03

申请人： Susan Banbury ,  Paivi Juujarvi ,  Leon Grother ,  Walter Lunsmann ,  Owen Murray ,  Juha-Matti Savola

发明人： Susan Banbury ,  Paivi Juujarvi ,  Leon Grother ,  Walter Lunsmann ,  Owen Murray ,  Juha-Matti Savola

IPC分类号： A61K9/20 ,  A61K31/4164

CPC分类号： A61K9/0056 ,  A61K9/006 ,  A61K9/2095 ,  A61K31/4164 ,  A61K47/26 ,  A61K47/42

摘要： Improved formulations containing substituted imidazole derivatives of the general formula 1, formula (I) wherein Y is —CH2— or —CO—, R1 is H, halo or hydroxy, R2 is H or halo, and R3 is H or lower alkyl (e.g. C1 to C4 alkyl, preferably C1 or C2 alkyl), or a pharmaceutically acceptable salt, such as an acid addition salt, e.g. the hydrochloride, of a compound of the general formula (I), are in solid fast-dispersing dosage form suitable for pre-gastric absorption.

摘要翻译： 含有通式1，式（I）的取代咪唑衍生物，其中Y是-CH 2 - 或-CO-，R 1 H的改进配方是H，卤素或羟基 R 2是H或卤素，并且R 3是H或低级烷基（例如C 1至C 4 烷基，优选C 1或C 2烷基）或其药学上可接受的盐，例如酸加成盐，例如 通式（I）化合物的盐酸盐是适合于胃前吸收的固体快速分散剂型。