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公开(公告)号:US06852491B2
公开(公告)日:2005-02-08
申请号:US09945943
申请日:2001-09-04
Applicant: Barbara J. Harris , John R. Hackett, Jr. , Priscilla Swanson , Klara Abravaya , Sushil G. Devare , Jacek J. Gorzowski , Claudia A. Esping , Ning Tang
Inventor: Barbara J. Harris , John R. Hackett, Jr. , Priscilla Swanson , Klara Abravaya , Sushil G. Devare , Jacek J. Gorzowski , Claudia A. Esping , Ning Tang
IPC: G01N33/53 , C12N15/09 , C12Q1/68 , C12Q1/70 , G01N33/569
CPC classification number: C12Q1/703
Abstract: Oligonucleotide primer sets, probes, and combinations of the primer sets and probes are provided herein. These reagents are useful for amplifying and detecting HIV-1 target sequences in a test sample.
Abstract translation: 本文提供寡核苷酸引物组,探针以及引物组和探针的组合。 这些试剂可用于扩增和检测试验样品中的HIV-1靶序列。
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公开(公告)号:US08183349B2
公开(公告)日:2012-05-22
申请号:US12828161
申请日:2010-06-30
Applicant: Xiaoxing Qiu , John R. Hackett, Jr. , Ka-Cheung X. Luk , Priscilla Swanson
Inventor: Xiaoxing Qiu , John R. Hackett, Jr. , Ka-Cheung X. Luk , Priscilla Swanson
IPC: C07K16/18
CPC classification number: C07K16/1036 , A61K39/00 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2319/00 , C07K2319/21 , C12N2740/13022
Abstract: The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an immunogenic response as well as XMRV-related nucleic acids having significant diagnostic, screening, and therapeutic utilities.
Abstract translation: 本发明一般涉及用于检测嗜酸性白血病病毒相关逆转录病毒(“XMRV”)和与XMRV感染有关的疾病的检测方法。 此外,本发明涉及能够诱导免疫原性应答的特异性XMRV抗原以及具有显着诊断,筛选和治疗效用的XMRV相关核酸。
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公开(公告)号:US20110135674A1
公开(公告)日:2011-06-09
申请号:US12828174
申请日:2010-06-30
Applicant: XIAOXING QIU , JAYDIP DAS GUPTA , JOHN R. HACKETT, JR. , KA-CHEUNG X. LUK , ROBERT SILVERMAN , PRISCILLA SWANSON
Inventor: XIAOXING QIU , JAYDIP DAS GUPTA , JOHN R. HACKETT, JR. , KA-CHEUNG X. LUK , ROBERT SILVERMAN , PRISCILLA SWANSON
IPC: A61K39/00 , C07K14/00 , G01N33/53 , C07H21/04 , C12N15/63 , C12N5/10 , C12Q1/68 , A61K31/7105 , A61P35/00 , A61P37/04 , A61P31/14
CPC classification number: C07K16/1036 , A61K39/00 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2319/00 , C07K2319/21 , C12N2740/13022
Abstract: The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an immunogenic response as well as XMRV-related nucleic acids having significant diagnostic, screening, and therapeutic utilities.
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公开(公告)号:US20120171235A1
公开(公告)日:2012-07-05
申请号:US13414356
申请日:2012-03-07
Applicant: Xiaoxing Qiu , John R. Hackett, JR. , Ka-Cheung X. Luk , Priscilla Swanson
Inventor: Xiaoxing Qiu , John R. Hackett, JR. , Ka-Cheung X. Luk , Priscilla Swanson
CPC classification number: C07K16/1036 , A61K39/00 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2319/00 , C07K2319/21 , C12N2740/13022
Abstract: The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an immunogenic response as well as XMRV-related nucleic acids having significant diagnostic, screening, and therapeutic utilities.
Abstract translation: 本发明一般涉及用于检测嗜酸性白血病病毒相关逆转录病毒(“XMRV”)和与XMRV感染有关的疾病的检测方法。 此外,本发明涉及能够诱导免疫原性应答的特异性XMRV抗原以及具有显着诊断,筛选和治疗效用的XMRV相关核酸。
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公开(公告)号:US20110137015A1
公开(公告)日:2011-06-09
申请号:US12828161
申请日:2010-06-30
Applicant: XIAOXING QIU , JOHN R. HACKETT, JR. , KA-CHEUNG X. LUK , PRISCILLA SWANSON
Inventor: XIAOXING QIU , JOHN R. HACKETT, JR. , KA-CHEUNG X. LUK , PRISCILLA SWANSON
IPC: C07K16/18
CPC classification number: C07K16/1036 , A61K39/00 , C07K14/005 , C07K2317/21 , C07K2317/34 , C07K2317/76 , C07K2319/00 , C07K2319/21 , C12N2740/13022
Abstract: The present invention relates generally to assays for the detection of Xenotropic Murine Leukemia Virus-related Retrovirus (“XMRV”) and diseases associated with XMRV infection. Additionally, the invention relates to specific XMRV antigens capable of inducing an immunogenic response as well as XMRV-related nucleic acids having significant diagnostic, screening, and therapeutic utilities.
Abstract translation: 本发明一般涉及用于检测嗜酸性白血病病毒相关逆转录病毒(“XMRV”)和与XMRV感染有关的疾病的检测方法。 此外,本发明涉及能够诱导免疫原性应答的特异性XMRV抗原以及具有显着诊断,筛选和治疗效用的XMRV相关核酸。
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