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公开(公告)号：US4785795A
公开(公告)日：1988-11-22
申请号：US8061
申请日：1987-01-14
Applicant: Param I. Singh
Inventor： Param I. Singh
CPC classification number: A61M1/1072 , A61M1/1082 , A61M1/125 , A61M1/107
Abstract: Disclosed is a high-frequency intra-arterial cardiac support system having a balloon pump which may be positioned in a major artery downstream of a natural heart. The balloon pump comprises a pumping balloon of small displacement mounted upon and cyclically inflatable and deflatable by fluid flow through catheter having a lumen leading to the outside of the body. The balloon pump further comprises a valve mounted downstream of the pumping balloon. The system further comprises a control and drive mechanism for providing cyclical fluid flow to the lumen of the catheter for inflation and deflation of the pumping balloon. The cyclical flow and the cyclical inflation and deflation occur at a frequency which is at least three times the normal beating frequency of the natural heart. The small displacement of the pumping balloon is much smaller than the normal stroke volume of the natural heart.
Abstract translation: 公开了一种具有球囊泵的高频动脉内心脏支持系统，其可以位于天然心脏下游的主动脉中。 气囊泵包括小排量的泵送气囊，其安装在可通过导管的流体流动并循环地充气并且可通过导管充气并且可通过具有通向身体外部的内腔的导管放气。 气囊泵还包括安装在泵送气囊下游的阀。 该系统还包括控制和驱动机构，用于向导管的内腔提供循环流体流，用于泵送气囊的充气和放气。 周期性流动和周期性通货膨胀和通货紧缩的发生频率至少是天然心脏正常跳动频率的三倍。 泵送气球的小位移远小于天然心脏的正常搏动体积。
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公开(公告)号：US4888009A
公开(公告)日：1989-12-19
申请号：US926816
申请日：1986-10-31
Applicant: David M. Lederman , Param I. Singh , Clair L. Strohl, Jr.
Inventor： David M. Lederman , Param I. Singh , Clair L. Strohl, Jr.
IPC: A61F2/24
CPC classification number: A61F2/2412 , Y10S623/90
Abstract: A prosthetic heart valve comprises a suture ring supporting a stent which surrounds a conduit bearing a plurality of flexible valve leaflets. The conduit extends beyond the end of the suture ring.
Abstract translation: 假体心脏瓣膜包括支撑支架的缝合环，支架围绕包含多个柔性瓣膜小叶的导管。 导管延伸超过缝线环的端部。
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公开(公告)号：US4259988A
公开(公告)日：1981-04-07
申请号：US76385
申请日：1979-09-17
Applicant: Param I. Singh
Inventor： Param I. Singh
CPC classification number: F15C3/04 , F15C7/00 , Y10T137/2109 , Y10T137/2115
Abstract: A vortex-diode check valve comprises a short cylindrical working chamber with an axial inlet port entering axially through a first end wall at a short distance from the central portion of a second end wall and a tangential outlet port exiting tangentially through a circular side wall. The ratio of fluid flow resistances, between flows in the reverse and forward directions, is markedly increased by configuring at least one end wall as a flexible resilient diaphragm, permitting relative motion between the second end wall and the axial inlet port.
Abstract translation: 涡流二极管止回阀包括短的圆柱形工作室，其轴向入口端口通过第一端壁在距离第二端壁的中心部分短的距离处和通过圆形侧壁切向出口的切向出口端口进入。 通过将至少一个端壁构造为柔性弹性隔膜，允许在第二端壁和轴向入口之间的相对运动，在反向和向前方向上的流之间的流体流动阻力的比率显着增加。
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Patent Agency Ranking
公开(公告)号：US4784648A
公开(公告)日：1988-11-15
申请号：US907413
申请日：1986-09-15
Applicant: Param I. Singh , Saul Stricker
Inventor： Param I. Singh , Saul Stricker
CPC classification number: A61M5/141 , A61M5/16854
Abstract: In an infusion system, a source of pressurized liquid infusate is connected to the upstream end of a small-bore flow restrictor and drives a flow of infusate therethrough; the downstream end of the flow restrictor is connected to the patient. The infusate at the upstream end is in communication with an annulus inflatable by infusate pressure of at least 200 to 500 Torr; the infusate at the downstream end is in communication with another annulus inflatable by infusate pressure of only 35 to 110 Torr, as occurs during infiltration. Inflation of an annulus provides a visible indication and can provide electrical contact for an alarm.
Abstract translation: 在输液系统中，加压液体输入源连接到小口径流量限制器的上游端，并且通过其输送输注物流; 流量限制器的下游端连接到病人身上。 上游端的输液管与通过至少200至500托的输注压力可膨胀的环形空间连通; 下游端的输液管与另外一个通过渗透压力仅为35至110乇的气泡充气连通。 环形通风提供了可见的指示，并且可以为报警提供电气接触。
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公开(公告)号：US4902272A
公开(公告)日：1990-02-20
申请号：US63648
申请日：1987-06-17
Applicant: Fredric L. Milder , Robert T. V. Kung , David M. Lederman , Param I. Singh
Inventor： Fredric L. Milder , Robert T. V. Kung , David M. Lederman , Param I. Singh
IPC: A61M1/10
CPC classification number: A61M1/1072
Abstract: An intra-arterial cardiac support system including multiple balloons for placement in the descending aorta with one balloon serving as a pumping balloon and one or more balloons serving as valve balloons, at least one of the valve balloons being positioned distal to the natural heart. The balloons are individually inflated and deflated to provide for sequential pumping action, with the sequence operating in timed relation to the sytstole and diastole of the natural heart.
Abstract translation: 一种动脉内心脏支持系统，包括用于放置在降主动脉中的多个气球，一个气囊用作泵送气囊，一个或多个气囊用作阀球，至少一个气囊位于自然心脏的远侧。 气球被单独充气和放气以提供顺序的泵送动作，其顺序与天然心脏的舒张和舒张时间关系。
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公开(公告)号：US4888011A
公开(公告)日：1989-12-19
申请号：US216028
申请日：1988-07-07
Applicant: Robert T. V. Kung , Param I. Singh
Inventor： Robert T. V. Kung , Param I. Singh
CPC classification number: A61M1/1086 , A61M1/106 , A61M1/1062 , A61M1/1065 , A61M1/1037 , A61M1/12
Abstract: An artificial heart system employing left and right pumping chambers each divided by a membrane into a blood pumping chamber and a hydraulic pumping chamber and a hydraulic pumping system for alternately pumping hydraulic fluid from said left hydraulic chamber toward said right hydraulic chamber and vice versa. A balancing chamber including a flexible membrane placed in the left atrium so that the membrane changes position with changes in the patient's blood pressure, the hydraulic portion of said balancing chamber being fluidically coupled to the right hydraulic pumping chamber in order to allow for a different pumping volume between the left blood pumping chamber and the right blood pumping chamber. A control system employing an algorithm to control the speed of the hydraulic pumping and the direction of flow of the hydraulic pumping in response to sensors sensing the left atrial pressure and the completeness of stroke of the left blood pumping chamber.
Abstract translation: 一种人造心脏系统，其采用左右抽吸腔室，每个腔室由隔膜分成血液泵送腔室和液压泵送腔室以及液压泵送系统，用于将液压流体从所述左液压腔室泵送到所述右液压腔室，反之亦然。 一种平衡室，包括放置在左心房中的柔性膜，使得膜随着患者血压的变化而改变位置，所述平衡室的液压部分流体耦合到右液压泵送室，以允许不同的泵送 左侧血液泵腔和右侧血液泵腔之间的体积。 一种采用算法控制液压泵送速度和液压泵送方向的控制系统，以响应感测左心房压力的传感器和左血泵腔的中风完整性。
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公开(公告)号：US4782817A
公开(公告)日：1988-11-08
申请号：US55648
申请日：1987-05-29
Applicant: Param I. Singh , William J. Bolt , Dana C. Sawyer
Inventor： Param I. Singh , William J. Bolt , Dana C. Sawyer
CPC classification number: A61M1/1086 , A61M1/1037
Abstract: An extracorporate ventricular support system includes a two bladder pump employing continuous gravity fill to the first bladder, while the second bladder is pneumatically driven to produce a pulsatile blood flow. A processor responds to air flow in the pneumatic drive line to control the pump through an electromagnetic valve supplying pressurized air. The program controls the output of blood volume per stroke to meet a target value.
Abstract translation: 一个公司内心室支持系统包括一个双重膀胱泵，其采用连续重力填充到第一膀胱，而第二膀胱被气动驱动以产生脉动血流。 处理器响应气动驱动线路中的气流，以通过供应加压空气的电磁阀来控制泵。 程序控制每搏输血量的输出以达到目标值。
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公开(公告)号：US4626243A
公开(公告)日：1986-12-02
申请号：US749470
申请日：1985-06-21
Applicant: Param I. Singh , David C. de Sieyes
Inventor： Param I. Singh , David C. de Sieyes
CPC classification number: A61M5/1483 , A61M5/141 , A61M5/148
Abstract: An infusion system utilizing a pressurized source of infusate comprises a capillary tube flow restrictor having sufficient length and suitably large ratio of length to internal diameter to provide reliably repeatable fluid resistance and minimum damage to infusate. The internal diameter of the flow restrictor may be made to decrease with increasing temperature so that the flow rate of the infusate is substantially independent of temperature. The flow restrictor may include means for indicating pressures and flow of infusate.
Abstract translation: 使用加压灌注源的输液系统包括毛细管限流器，其具有足够的长度和适当大的长度与内径的比率，以提供可靠的可重复的流体阻力和对灌输液的最小的损伤。 流量限制器的内径可以随着温度的升高而降低，使得输液管的流速基本上与温度无关。 限流器可以包括用于指示压力和灌注液流动的装置。
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