公开(公告)号：US08781197B2

公开(公告)日：2014-07-15

申请号：US12990148

申请日：2009-04-28

申请人： Yi Wang ,  Ludovic de Rochefort ,  Bryan Kressler ,  Tian Liu ,  Pascal Spincemaille

发明人： Yi Wang ,  Ludovic de Rochefort ,  Bryan Kressler ,  Tian Liu ,  Pascal Spincemaille

IPC分类号： G06K9/00

CPC分类号： G01R33/54 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/563

摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.

摘要翻译： 提供了用于磁源磁共振成像的方法和装置。 该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示， 例如磁化率的定量估计。 附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。 通过基于收集的信号和附加信息的反转操作来生成图像。 反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。 此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

公开(公告)号：US07941204B1

公开(公告)日：2011-05-10

申请号：US11281920

申请日：2005-11-16

申请人： Yi Wang ,  Pascal Spincemaille ,  Thanh D. Nguyen

发明人： Yi Wang ,  Pascal Spincemaille ,  Thanh D. Nguyen

IPC分类号： A61B5/05 ,  G01V3/00

CPC分类号： A61B5/055 ,  G01R33/4824 ,  G01R33/5602 ,  G01R33/5607 ,  G01R33/561 ,  G01R33/5614 ,  G01R33/5635 ,  G01R33/5676

摘要： Methods of acquiring magnetic resonance imaging (MRI) data for angiography. The present invention includes novel magnetization preparation schemes where the navigator and fat saturation pulses are executed in steady state after the preparatory pulses in order to minimize the delay between the magnetization preparation and the image echoes. The present invention also provides for improved methods of contrast-enhanced MRI where data are collected along non-linear trajectories through k-space and may also involve novel view ordering. In addition, the present methods employ novel motion corrections that minimize motion artifacts. The present invention further provides novel methods of self-calibrated sensitivity-encoded parallel imaging that allow for accurate and rapid scanning of subjects.

摘要翻译： 获取血管造影的磁共振成像（MRI）数据的方法。 本发明包括新颖的磁化准备方案，其中导航器和脂肪饱和脉冲在准备脉冲之后以稳定的状态执行，以使磁化准备和图像回波之间的延迟最小化。 本发明还提供了对比增强MRI的改进方法，其中数据通过k空间沿着非线性轨迹被收集，并且还可以涉及新颖的视图排序。 此外，本方法采用使运动伪影最小化的新的运动校正。 本发明还提供允许对被摄体进行精确和快速扫描的自校准灵敏度编码并行成像的新颖方法。

公开(公告)号：US20110044524A1

公开(公告)日：2011-02-24

申请号：US12990148

申请日：2009-04-28

申请人： Yi Wang ,  Ludovic de Rochefort ,  Bryan Kressler ,  Tian Liu ,  Pascal Spincemaille

发明人： Yi Wang ,  Ludovic de Rochefort ,  Bryan Kressler ,  Tian Liu ,  Pascal Spincemaille

IPC分类号： G06K9/00

CPC分类号： G01R33/54 ,  G01R33/5601 ,  G01R33/5608 ,  G01R33/563

摘要： A method and apparatus is provided for magnetic source magnetic resonance imaging. The method includes collecting energy signals from an object, providing additional information of characteristics of the object, and generating the image of the object from the energy signals and from the additional information such that the image includes a representation of a quantitative estimation of the characteristics, e.g a quantitative estimation of magnetic susceptibility. The additional information may comprise predetermined characteristics of the object, a magnitude image generated from the object, or magnetic signals collected from different relative orientations between the object and the imaging system. The image is generated by an inversion operation based on the collected signals and the additional information. The inversion operation minimizes a cost function obtained by combining the data extracted from the collected signals and the additional information of the object. Additionally, the image is used to detect a number of diagnostic features including microbleeds, contract agents and the like.

摘要翻译： 提供了用于磁源磁共振成像的方法和装置。 该方法包括从对象收集能量信号，提供对象的特征的附加信息，以及从能量信号和附加信息生成对象的图像，使得图像包括特征的定量估计的表示， 例如磁化率的定量估计。 附加信息可以包括对象的预定特征，从对象产生的幅度图像，或从物体和成像系统之间的不同相对取向收集的磁信号。 通过基于收集的信号和附加信息的反转操作来生成图像。 反转操作最小化通过组合从所收集的信号提取的数据和对象的附加信息而获得的成本函数。 此外，该图像用于检测多个诊断特征，包括微出血，合同代理等。

公开(公告)号：US08200311B2

公开(公告)日：2012-06-12

申请号：US11737812

申请日：2007-04-20

申请人： Pascal Spincemaille ,  Yi Wang ,  Martin R. Prince

发明人： Pascal Spincemaille ,  Yi Wang ,  Martin R. Prince

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0263 ,  A61B5/0402 ,  A61B5/7285 ,  G01R33/4818 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56509 ,  G01R33/5673

摘要： Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.

摘要翻译： 描述了一种用于持续对比增强磁共振血管造影（CE-MRA）的k空间的鲁棒心电图（ECG）排序技术，其获得舒张期的无运动部分中的k空间的中心部分并从周边填充 的k空间在其他时间。 为了最大限度地利用对比度增强，即使当ECG信号丢失时也可以连续获取数据。 ECG信号被实时监控。 ECG排序技术允许灵活的采集矩阵，并且针对ECG信号缺陷是鲁棒的。 与常规门控序列相比，ECG排序技术允许具有更高分辨率的胸廓和肺部磁共振血管造影。

公开(公告)号：US20070287907A1

公开(公告)日：2007-12-13

申请号：US11737812

申请日：2007-04-20

申请人： Pascal Spincemaille ,  Yi Wang ,  Martin R. Prince

发明人： Pascal Spincemaille ,  Yi Wang ,  Martin R. Prince

IPC分类号： A61B5/055

CPC分类号： A61B5/055 ,  A61B5/0263 ,  A61B5/0402 ,  A61B5/7285 ,  G01R33/4818 ,  G01R33/5601 ,  G01R33/5635 ,  G01R33/56509 ,  G01R33/5673

摘要： Described is a robust electrocardiogram (ECG) ordering technique of k-space for breath hold contrast enhanced magnetic resonance angiography (CE-MRA) that acquires the central part of k-space in a motion-free portion of diastole and fills in from the periphery of k-space at all other times. To make maximal use of the contrast enhancement, data is acquired continuously even when the ECG signal is lost. The ECG signal is monitored in real time. The ECG ordering technique allows a flexible acquisition matrix and is robust against ECG signal imperfections. The ECG ordering technique allows thoracic and pulmonary magnetic resonance angiography with a higher resolution when compared to the conventional gated sequence.

摘要翻译： 描述了一种用于持续对比增强磁共振血管造影（CE-MRA）的k空间的鲁棒心电图（ECG）排序技术，其获得舒张期的无运动部分中的k空间的中心部分并从周边填充 的k空间在其他时间。 为了最大限度地利用对比度增强，即使当ECG信号丢失时也可以连续获取数据。 ECG信号被实时监控。 ECG排序技术允许灵活的采集矩阵，并且针对ECG信号缺陷是鲁棒的。 与常规门控序列相比，ECG排序技术允许具有更高分辨率的胸廓和肺部磁共振血管造影。