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    Pyrrole-2,5-dithione derivatives as liver x receptor modulators
    4.
    发明申请
    Pyrrole-2,5-dithione derivatives as liver x receptor modulators 审中-公开
    吡咯-2,5-二硫酮衍生物作为肝脏x受体调节剂

    公开(公告)号：US20060189663A1

    公开(公告)日：2006-08-24

    申请号：US10563676

    申请日：2004-07-08

    申请人： Patrik Holm

    发明人： Patrik Holm

    IPC分类号： A61K31/4439 ,  A61K31/405 ,  A61K31/4025 ,  A61K31/4015 ,  C07D405/02 ,  C07D403/02

    CPC分类号： C07D207/44 ,  C07D401/06

    摘要： The present invention relates to certain novel compounds of the Formula I to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR) α (NR1H3) and/or β (NR1H2) and in treating clinical conditions including cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer's disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of the metabolic syndrome, to methods for their therapeutic use and to pharmaceutical compositions containing them.

    摘要翻译： 本发明涉及一些式I化合物的制备方法，用于调节核激素受体肝X受体（LXR）α（NR1H3）和/或β（NR1H2）和治疗临床中的用途 包括心血管疾病如动脉粥样硬化的病症; 炎性疾病，阿尔茨海默病，与胰岛素抵抗相关的脂质紊乱（血脂异常），2型糖尿病和代谢综合征的其他表现，其治疗用途的方法和含有它们的药物组合物。

    ADJUSTMENT SYSTEM FOR THE PITCH ANGLE OF A WIND TURBINE
    5.
    发明申请
    ADJUSTMENT SYSTEM FOR THE PITCH ANGLE OF A WIND TURBINE 审中-公开
    风力发电机倾斜角调整系统

    公开(公告)号：US20130039762A1

    公开(公告)日：2013-02-14

    申请号：US13558680

    申请日：2012-07-26

    申请人： Juhani EKOLA ,  Patrik HOLM

    发明人： Juhani EKOLA ,  Patrik HOLM

    IPC分类号： F03D1/06 ,  F03D7/02

    CPC分类号： F03D7/0224 ,  F05B2260/76 ,  F05B2260/79 ,  Y02E10/721 ,  Y02E10/723

    摘要： Adjustment system for the pitch angle of a wind turbine, which wind turbine includes an axis of rotation that is horizontal or at a small angle with respect to the horizontal plane, and a rotating hub to which the blades are connected in a manner allowing their slewing, in which system an adjustment arrangement is arranged inside the hub and/or shaft. The arrangement includes a drive device moving in the direction of the axis of rotation as well as an adjustment cylinder apparatus or corresponding for moving it. Rod-shaped control parts for each blade are connected in a hinged manner to the drive device. The control parts are connected to the butt part of each blade such that the pitch angle can be adjusted by shifting the drive device.

    摘要翻译： 用于风力涡轮机的俯仰角的调节系统，该风力涡轮机包括相对于水平平面水平或以小角度的旋转轴线，以及以允许其回转的方式连接叶片的旋转轮毂 在该系统中，调节装置布置在轮毂和/或轴内。 该装置包括沿着旋转轴线的方向移动的驱动装置以及调节滚筒装置或对应于其移动的驱动装置。 用于每个叶片的杆形控制部件以铰接方式连接到驱动装置。 控制部件连接到每个叶片的对接部分，使得可以通过移动驱动装置来调节桨距角。

    Wind power station
    8.
    发明授权
    Wind power station 有权
    风电站

    公开(公告)号：US08847422B2

    公开(公告)日：2014-09-30

    申请号：US13504837

    申请日：2009-10-29

    申请人： Patrik Holm

    发明人： Patrik Holm

    IPC分类号： F03D11/00 ,  F03D7/02

    CPC分类号： F03D11/0008 ,  F03D7/0204 ,  F03D80/70 ,  Y02E10/722 ,  Y02E10/723

    摘要： Wind power station, which includes a vertical tower (1), a rotor that includes a hub part (18) and blades (16) that is fitted to the top end of the tower and that is aligned into the wind and rotated by the wind, a rotor shaft (11), which transmits rotating motion to a generator (12, 13, 14) connected to the aforementioned shaft in a direct-drive power station and to a gear box in a geared power station, and also a revolving frame (10) that is fitted to the top end of the tower (1) on bearings so as to rotate around the vertical axis (17), in which frame the rotor shaft (11) is also mounted on bearings. For mounting the revolving frame (10) on bearings onto the top part of the tower, the top part of the tower (1) includes a first bearing (5) or (20) that mainly bears at least the vertical load coming from the revolving frame (10), as well as a second bearing (9) or (19) disposed at a distance H from the aforementioned bearing, in which case one of the bearings (9), (19) bears mainly the radial load coming from the revolving frame and in which case the support of the upper one of the aforementioned bearings (9), (19, 20) is arranged by means of a support piece leaving the tower and fitted inside the revolving frame.

    摘要翻译： 包括垂直塔（1）的风力发电站，包括轮毂部分（18）和叶片（16）的转子，所述转子安装在塔顶部并且被排列成风并由风旋转 ，转子轴（11），其将旋转运动传递到在直接驱动发电站中连接到上述轴的发电机（12,13,14）和齿轮箱中的齿轮箱，以及旋转框架 （10），其在轴承上安装在塔架（1）的顶端上，以围绕垂直轴线（17）旋转，转子轴（11）的框架也安装在轴承上。 为了将旋转框架（10）安装在轴承上的塔架顶部上，塔架（1）的顶部包括第一轴承（5）或（20），其主要至少承受来自旋转的 框架（10）以及与上述轴承设置成距离H的第二轴承（9）或（19），在这种情况下，一个轴承（9），（19）主要承受来自 在这种情况下，上述轴承（9），（19,20）中的上一个的支撑件通过离开塔架的支撑件布置并装配在旋转框架内。

    5-Thioxo-1,5-Dihydro-2H-Pyrrol-2-One Derivatives As Liver X Receptor Modulators
    10.
    发明申请
    5-Thioxo-1,5-Dihydro-2H-Pyrrol-2-One Derivatives As Liver X Receptor Modulators 审中-公开
    5-硫代-1,5-二氢-2H-吡咯-2-酮衍生物作为肝X受体调节剂

    公开(公告)号：US20080255207A1

    公开(公告)日：2008-10-16

    申请号：US11813467

    申请日：2006-01-09

    申请人： Patrik Holm ,  Lanna Li

    发明人： Patrik Holm ,  Lanna Li

    IPC分类号： A61K31/4439 ,  C07D401/12

    CPC分类号： C07D207/44 ,  C07D401/06 ,  C07D403/12 ,  C07D405/12

    摘要： The present invention relates to certain novel compounds of the Formula (I) to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR) α(NR1H3) and/or β(NR1H2) and in treating clinical conditions including cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer's disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of the metabolic syndrome, to methods for their therapeutic use and to pharmaceutical compositions containing them.

    摘要翻译： 本发明涉及式（I）的某些新型化合物，用于制备这些化合物，用于调节核激素受体肝X受体（LXR）α（NR1H3）和/或β（NR1H2）和在 治疗包括心血管疾病如动脉粥样硬化的临床病症; 炎性疾病，阿尔茨海默病，与胰岛素抵抗相关的脂质紊乱（血脂异常），2型糖尿病和代谢综合征的其他表现，其治疗用途的方法和含有它们的药物组合物。