公开(公告)号：US20110280927A1

公开(公告)日：2011-11-17

申请号：US13130233

申请日：2009-11-20

Applicant: Abraham Araya ,  Alan Reginald Minihan ,  Paul Matthew Robbins ,  Sonya Theresa Broderick ,  Michael J. Waring

Inventor： Abraham Araya ,  Alan Reginald Minihan ,  Paul Matthew Robbins ,  Sonya Theresa Broderick ,  Michael J. Waring

IPC: A61L15/18 ,  A61K33/34 ,  A61K33/32 ,  A61K33/38 ,  A61K33/26 ,  A61K33/30 ,  A61P17/02 ,  A61P15/10 ,  A61P15/00 ,  A61P9/08 ,  A61P17/00 ,  A61P25/00 ,  A61P29/00 ,  A61K33/00 ,  A61K33/06

CPC classification number: A61L26/0052 ,  A61L15/18 ,  A61L15/44 ,  A61L15/58 ,  A61L26/0004 ,  A61L26/0066 ,  A61L2300/114 ,  A61L2300/602 ,  A61L2300/802

Abstract: A dressing composition for use as a skin dressing comprises an elastomeric-adhesive composition, and a zeolite comprising releasably adsorbed nitric oxide. The zeolite may comprise a transition metal cation such as Co, Fe, Mn, Ni, Cu, Zn, Ag or a mixture thereof as an extra-framework metal cation, preferably Zn. The elastomeric adhesive composition may be a hydrocolloid-adhesive composition comprising, hydrocolloid and elastomer. The dressing composition releases nitric oxide, which may have beneficial effects, when used on wounds or moist skin, with a substantially constant release rate over a long period of time. A dressing including a layer of the dressing composition has a backing layer and may have a release liner removably attached to the skin-contacting surface of the dressing layer.

Abstract translation: 用作皮肤敷料的敷料组合物包括弹性体粘合剂组合物和包含可释放地吸附的一氧化氮的沸石。 沸石可以包含过渡金属阳离子如Co，Fe，Mn，Ni，Cu，Zn，Ag或其作为外框架金属阳离子，优选Zn的混合物。 弹性体粘合剂组合物可以是包含水胶体和弹性体的水胶体粘合剂组合物。 敷料组合物释放一氧化氮，当用于伤口或潮湿的皮肤上时，其可能具有有益效果，并且在长时间内具有基本恒定的释放速率。 包括敷料组合物层的敷料具有背衬层，并且可以具有可移除地附接到敷料层的皮肤接触表面的剥离衬垫。