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公开(公告)号：US09162984B2
公开(公告)日：2015-10-20
申请号：US12593673
申请日：2008-03-28
IPC分类号： A61K8/49 , C07D215/54 , A61K31/47 , C07D211/14 , C07D261/18 , C07D307/68 , C07D405/06
CPC分类号： C07D215/54 , A61K8/4926 , A61K8/4953 , A61K8/4973 , A61K8/69 , A61Q17/04 , A61Q19/04 , C07D211/14 , C07D261/18 , C07D307/68 , C07D405/06
摘要： The present invention relates to small molecule modulators of melanin expression and methods of making the small molecules. Also disclosed are methods of increasing pigmentation in a cell which involve providing compounds of the present invention and contacting a cell with the compounds under conditions effective to induce melanin expression in the cell, thereby increasing pigmentation. The present invention also relates to compositions containing compounds of the present invention and a carrier.
摘要翻译： 本发明涉及黑色素表达的小分子调节剂和制备小分子的方法。 还公开了增加细胞色素沉着的方法，其涉及提供本发明的化合物，并且在有效诱导细胞黑色素表达的条件下使细胞与化合物接触，从而增加色素沉着。 本发明还涉及含有本发明化合物和载体的组合物。
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公开(公告)号：US20100233106A1
公开(公告)日：2010-09-16
申请号：US12593673
申请日：2008-03-28
IPC分类号： A61K8/49 , C07D215/14 , C07D405/02 , C07D413/02 , C07D403/02 , C12N5/00 , A61K31/47 , A61K31/4709 , C07D307/34 , C07D333/04 , C07D207/30 , C07D413/12 , C07D401/12
CPC分类号： C07D215/54 , A61K8/4926 , A61K8/4953 , A61K8/4973 , A61K8/69 , A61Q17/04 , A61Q19/04 , C07D211/14 , C07D261/18 , C07D307/68 , C07D405/06
摘要： The present invention relates to small molecule modulators of melanin expression and methods of making the small molecules. Also disclosed are methods of increasing pigmentation in a cell which involve providing compounds of the present invention and contacting a cell with the compounds under conditions effective to induce melanin expression in the cell, thereby increasing pigmentation. The present invention also relates to compositions containing compounds of the present invention and a carrier.
摘要翻译： 本发明涉及黑色素表达的小分子调节剂和制备小分子的方法。 还公开了增加细胞色素沉着的方法，其涉及提供本发明的化合物，并且在有效诱导细胞黑色素表达的条件下使细胞与化合物接触，从而增加色素沉着。 本发明还涉及含有本发明化合物和载体的组合物。
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