公开(公告)号：US20080027328A1

公开(公告)日：2008-01-31

申请号：US11759041

申请日：2007-06-06

申请人： Peter Klopotek ,  Peter Litman

发明人： Peter Klopotek ,  Peter Litman

IPC分类号： A61N7/00

CPC分类号： A61N7/00 ,  A61B5/01 ,  A61B8/0858 ,  A61B8/4281 ,  A61B2017/00761 ,  A61N7/02 ,  G10K11/30 ,  G10K11/32

摘要： Methods and apparatus are disclosed for applying acoustic energy to the skin. Acoustic waveguides with elements of varying thickness or shape are disclosed which deliver energy to more than one depth below a surface of the skin substantially simultaneously. The invention is especially useful with devices that focus ultrasound energy by condensing a propagating wavefront. The invention compensates for the mismatch in acoustic properties of the device's waveguide and the biological tissue that typically cause portions of the collapsing wavefront to lag behind other portions and, thereby, limit the focusing capabilities of acoustic treatment devices.

摘要翻译： 公开了用于向皮肤施加声能的方法和装置。 公开了具有不同厚度或形状的元件的声波导，其基本上同时向皮肤表面下方的多于一个深度输送能量。 本发明对于通过聚焦传播波前聚焦超声波能量的装置特别有用。 本发明补偿了器件的波导和生物组织的声学特性不匹配，其通常导致部分塌陷波前滞后于其它部分，从而限制了声学处理装置的聚焦能力。

公开(公告)号：US06293938B1

公开(公告)日：2001-09-25

申请号：US08695115

申请日：1996-08-08

申请人： David F. Muller ,  Mike D'Agati ,  Marc Friedman ,  Troy Harmon ,  Peter Klopotek ,  Alex Sacharoff ,  Evan Sherr

发明人： David F. Muller ,  Mike D'Agati ,  Marc Friedman ,  Troy Harmon ,  Peter Klopotek ,  Alex Sacharoff ,  Evan Sherr

IPC分类号： A61F908

CPC分类号： A61F9/008 ,  A61F9/00804 ,  A61F9/00817 ,  A61F2009/00844 ,  A61F2009/00872

摘要： The invention features improvements in PRK procedures that relate to preventing non-uniform removal of material from the corneal surface. It has been realized that photoablation by-products resulting during the PRK procedure can affect the accuracy and the predictability of the procedure. Under certain conditions, the plume of photoablation by-products that have left the corneal surface can non-uniformly redeposit onto the ablation area and thus affect the uniformity of subsequent material removal. The plume of photoablation by-products, in the space above the corneal surface, can also non-uniformly affect the escape of further photoablation products from the surface. In addition to the plume effects, it has been realized that the hydration level of the corneal tissue during the PRK procedure can vary over the ablation area and likewise non-uniformly affect the PRK procedure.

摘要翻译： 本发明的特征在于PRK程序的改进涉及防止材料从角膜表面的不均匀去除。 已经意识到，在PRK过程中产生的光消除副产物可能影响程序的准确性和可预测性。 在某些条件下，离开角膜表面的光消融副产物的羽毛可能不均匀地再沉积到消融区域上，从而影响随后的材料去除的均匀性。 在角膜表面以上的空间中，光消融副产物的羽毛也可以不均匀地影响进一步的光消化产物从表面的逸出。 除了羽流效应之外，已经认识到在PRK程序期间角膜组织的水合水平可以在消融区域上变化，并且同样不均匀地影响PRK程序。

公开(公告)号：US20060184071A1

公开(公告)日：2006-08-17

申请号：US11295700

申请日：2005-12-06

申请人： Peter Klopotek

发明人： Peter Klopotek

IPC分类号： A61H1/00

CPC分类号： A61N7/02 ,  A61B2017/00761 ,  A61N7/00

摘要： Methods and apparatus are disclosed for applying acoustic energy to the skin whereby the wavefront can be controlled to confine the focused energy to a desired subsurface region. Acoustic waveguides are disclosed which compensate for distortions that otherwise occur when a focused acoustic beam crosses a boundary, such as the transition from a treatment device to a target region of skin. The invention is especially useful with devices that focus ultrasound energy by condensing a propagating wavefront. The invention compensates for the mismatch in acoustic properties of the device's waveguide and the biological tissue that typically cause portions of the collapsing wavefront to lag behind other portions and, thereby, limit the focusing capabilities of acoustic treatment devices.

摘要翻译： 公开了用于将声能施加到皮肤的方法和装置，由此可以控制波前以将聚焦的能量限制在期望的地下区域。 公开了声波导，其补偿当聚焦的声束穿过边界时所发生的变形，例如从治疗装置到皮肤的目标区域的转变。 本发明对于通过聚焦传播波前聚焦超声波能量的装置特别有用。 本发明补偿了器件的波导和生物组织的声学特性不匹配，其通常导致部分塌陷波前滞后于其它部分，从而限制了声学处理装置的聚焦能力。

公开(公告)号：US4797888A

公开(公告)日：1989-01-10

申请号：US65510

申请日：1987-06-23

申请人： Peter Klopotek

发明人： Peter Klopotek

IPC分类号： H01S3/0971 ,  H01S3/00

CPC分类号： H01S3/09713

摘要： A circuit for the preionization and main discharge of a pulsed gas laser provides that the sparks intended for the preionization of the working gas have an independent switch function. Capacitive energy storage means 7, 8, 9, 10 are connected low-inductively to the spark electrodes 3, 4, 5, 6. The current flowing in the spark discharge is used selectively for the preionization by means of the spark or for generating a compressed high-voltage pulse. The compressed high-voltage pulse is applied as prepulse to the main electrodes to momentarily greatly increase the voltage obtaining between the main electrodes and thus initiate and supply a homogeneous main discharge.

摘要翻译： 用于脉冲气体激光器的预电离和主放电的电路提供用于工作气体的前体化的火花具有独立的开关功能。 电容性能量存储装置7,8,9,10被低感应地连接到火花放电电极3,4,5,6。在火花放电中流动的电流被选择性地用于通过火花进行预电离或用于产生 压缩高压脉冲。 将压缩的高电压脉冲作为前脉冲施加到主电极，从而瞬间大大增加主电极之间的电压获得，从而启动并提供均匀的主放电。