摘要:
The present invention provides crystalline forms of Palonosetron hydrochloride, processes for their preparation and pharmaceutical compositions containing such crystalline forms of Palonosetron HCl.
摘要:
A phase locked magnetron comprises a cathode and anode and an interaction space in between. The cathode is coupled to an injected locking signal, which prompts the operation of the magnetron to be in phase with the phase of the locking signal. From a magnetron of the type in which the cathode is at a large negative potential, the coupling to the locking signal is by non-contact means, in particular, by extending the cathode into a waveguide in which the locking signal is present. An alternative arrangement is for a magnetron of the type in which the cathode is substantially at ground potential. In this arrangement the coupling is by direct electrical connection to a conductor having the injected locking signal.
摘要:
A low profile angular sensor assembly having a base member adapted for rotation about a spin axis and a generally planar gyroscopic element resiliently coupled to the base member for rotation therewith and for pivotal movement relative to the base member about a pivot axis orthogonal to the spin axis also includes a planar piezoelectric beam which is coupled to the base member and to the gyroscopic element so that it is substantially parallel to the gyroscopic element. The coupling is selectively compliant to isolate the piezoelectric beam from motion in the plane of the beam.
摘要:
A procedure for converting steroids characterized by presence of an 11.beta.OH group into potent corticoids having one or more substituents, such as 6.alpha.F, 16.alpha., 17.alpha.-hydroxy or isopropylidene dioxy, 16.alpha. or 16.beta. methyl, .DELTA..sup.1,4 ; by reacting the 11.beta.-hydroxy steroid with trichloromethyl siloxane steroid, thereby rendering the normally sensitive 11 substituent inert to the series of reactions which thereafter incorporate one or more of the desired above listed substituents into the steroid molecule. The siloxy group is then hydrolyzed to regenerate the 11.beta.-hydroxy substituent.Many of the trimethyl siloxy steroids are novel compounds.The siloxane may be selectively cleaved by reaction of the finely divided steroid with 40-60% aqueous HF.